abt-594 hydrochloride

Tebanicline hydrochloride (Ebanicline hydrochloride) 是一种有效的合成烟碱（non-opioid）镇痛药。

ABT-418 hydrochloride is a selective agonist of nAChRs with cognitive enhancing and anxiolytic activities. It activates cholinergic channel and can be used for the research of Alzheimer's disease.

DPNB-ABT 594 is a nitrobenzyl-caged ABT 594, a selective α4β2 nAChR agonist. One-photon uncaging evokes large inward currents and Ca2+transients on cell bodies and dendrites of medial habenular neurons in mouse brain slices. Two-photon uncaging induces fast nAChR-mediated currents. Photolyzed with high quantum yield of 0.20. Effective photolysis occurs using one- or two-photon excitation; one-photon uncaging requires illumination at 410 nm for 1.5-3 ms; two-photon uncaging requires illumination with appropriate two photon pulse laser at 710 nm for ~2 ms.

Potent non-nucleoside adenosine kinase inhibitor (IC50 = 1.7 nM), selective over other sites of adenosine interaction (A1, A2A and A3 receptors, adenosine transporter and adenosine deaminase). Displays oral activity in animal models of pain and inflammation.

ABT-702 hydrochloride，一种有效的腺苷激酶 (AK) 抑制剂，其IC50值为1.7 nM。

ABT-639 hydrochloride 是选择性的、新型的 T 型 Ca2+通道阻滞剂。

ABT-491 hydrochloride is an active platelet activator receptor (PAF-R) antagonist with good selectivity and oral administration.