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Search Results for " tobacco "

Targets Recommended: Others

33

抑制剂 & 化合物

22

天然产物

1

化合物库

1

重组蛋白

3

同位素标记化合物

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Cat. No.	Product Name
L6820	烟草单体化合物库		747 compounds
	747种烟草单体化合物的独特集合，可用于高通量筛选和高内涵筛选

化合物库

烟草单体化合物库

Cat.No: L6820

Compounds: 747

Cat. No.	Product Name	Target	Signaling Pathways
T20366	beta-Nicotyrine bata-碱二烯,Nicotyrine,alpha-Nicotyrine	Others	Others
	beta-Nicotyrine 是一种 Nicotine 的代谢物。它是一种微量的烟草生物碱，提取自普通烟草植物的叶子和香烟烟雾冷凝物。
T27679	JNJ-39393406	AChR	Neuroscience
	JNJ-39393406 是一种 α7 尼古丁乙酰胆碱受体正异位调节剂，可用于研究烟草依赖和阿尔茨海默病。
T1366	3-Pyridylacetic acid hydrochloride	DPP-4	Proteases/Proteasome
	3-Pyridylacetic acid hydrochloride （3-PAA-HCl）尼克酸的高同系物，是尼古丁（和其它烟草生物碱）的分解产物，还可与胺、醇和羧酸等反应，也可在反应中作为酸催化剂。
T11668	IQB-782	Others	Others
	IQB-782 是一种粘液溶解剂，具有粘液溶解祛痰活性。IQB-782 抑制凝血酶活化性纤维蛋白溶解抑制剂，保护大鼠免受烟草烟雾引起的呼吸道阻塞，可降低体外胃粘蛋白悬浮液的粘度，可用于研究阻塞性肺疾病。
T20533	NNK Nicotine-derived nitrosamine ketone	Lipoxygenase	Metabolism
	NNK (Nicotine-derived nitrosamine ketone) 是尼古丁亚硝化衍生物。它可以激活 ERK1/2和 PKCα，并在 Ser70 激活 Bcl2磷酸化，以及在 Thr58和 Ser62激活 c-Myc。它可用于构建肺癌小鼠模型，以及诱导人肺癌细胞的增殖和存活。
T10318	Anatabine dicitrate	NF-κB	NF-κB
	Anatabine dicitrate is a tobacco alkaloid that can cross the blood-brain barrier. It is a potent α4β2 nAChR agonist and inhibits NF-κB activation lower amyloid-β (Aβ) production by preventing the β-cleavage of the amyloid precursor protein.
T20781	Maleic hydrazide Antergon,Antyrost,Hydrazide maleique,Burtolin,抑芽丹	Others	Others
	Maleic hydrazide, a herbicide, inhibits the sprouting in vegetables and stored root crops, prevents sucker production in tobacco plants, controls the growth of foliage, and grass.
T36709	N’-Nitrosonornicotine	Others	Others
	N’-Nitrosonornicotine is a tobacco-specific N-nitrosamine and carcinogen that has been found in unburned tobacco and cigarette smoke.1It induces the formation of DNA adducts in isolated rat nasal mucosa and esophagus. N’-Nitrosonornicotine induces tumor formation in rat esophagus and nasal cavity, mouse lung, forestomach, and trachea, and hamster trachea and forebrain. Urinary levels of N’-nitrosonornicotine are positively correlated with the risk of esophageal cancer in smokers.2 1.Hecht, S....
T31573	DPX-3778	Others	Others
	DPX-3778 is the triethanolamine salt of 3-(p-chlorophenyl)-6-methoxy-s-triazine-2,4(1H,3H) dione, at concentrations of 0.124-2.48 μM enhanced ca. 4-5-fold the proliferation of tobacco (Nicotiana tabacum L. cv. Wisconsin 38) callus cultured in the presence
T23228	(R,S)-Anatabine (tartrate) (2743-90-0 free base) (R,S)-Anatabine (tartrate)	Others	Others
	Anatabine is a minor tobacco alkaloid with a chemical structural similarity to nicotine. Anatabine is produced in plants of the Solanacea family including tobacco, green tomatoes, peppers, and eggplants. Anatabine is an Aβ inhibitor. (R,S)-Anatabine (tart
T70383	Fenamidone	Others	Others
	Fenamidone is a foliar fungicide used on grapes, ornamentals, potatoes, tobacco, and vegetables. It exerts its fungicidal effects by acting as a Qo inhibitor.
T37276	2,5-Deoxyfructosazine (hydrochloride)	Others	Others
	2,5-Deoxyfructosazine is a pyrazine derivative that can be found in cured tobacco and is used as a flavoring agent in the food and tobacco industry. Pyrazines, including 2,5-deoxyfructosazine, can be produced either by pyrolytic decomposition of natural compounds or by the reaction of sugars with alcoholic ammonia. 2,5-Deoxyfructosazine is also formed by the breakdown of D-glucosamine at neutral pH. Like glucosamine, 2,5-deoxyfructosazine has DNA strand breakage activity and strongly inhibits IL...
T10308	AMPD2 inhibitor 1	Others	Others
	AMPD2 inhibitor 1 is an inhibitor of adenosine monophosphate deaminase 2 (AMPD2), used in the research of salt craving, sugar craving, umami craving, and addictions including tobacco, drug, nicotine and alcohol addictions.
T6060L	Anabasine HCl BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653	Others	Others
	Anabasine HCl is used as a clinical biomarker for tobacco smoke exposure and as an insecticide. It is also a depolarizing NMJ blocker, aromatase inhibitor, nAChr antagonist, and teratogen found in species of Nicotiana.
T79270	TMV-IN-6	Others	Others
	TMV-IN-6（Compound 4g）是抗病毒和杀真菌剂，其作用机制为结合烟草花叶病毒（TMV）CP，从而抑制病毒组装，并干扰TMVCP与RNA的组装过程。
T74713	TMV-IN-3	Others	Others
	TMV-IN-3是烟草花叶病毒(TMV)的抑制剂，属于查尔酮衍生物类。该化合物对TMV展现出抗病毒活性，其EC50为120.3 μg/mL，适用于感染、炎症以及肿瘤等研究领域。
T84400	5-methyl Chrysene NSC 407620	Others	Others
	5-Methylchrysene, a carcinogenic polycyclic aromatic hydrocarbon with four fused rings, functions as an aryl hydrocarbon receptor agonist. It is generated through the incomplete combustion of organic matter and primarily detected in gasoline exhaust and tobacco smoke. Additionally, 5-Methylchrysene can be converted into mutagenic metabolites by cytochrome P450 enzymes 1A1 and 1B1.
T82666	Crustacean cardioactive peptide CCAP
	CCAP（Crustacean cardioactive peptide）为一种具有调节昆虫心脏功能的非极性肽，由9个氨基酸组成，最初自tobacco hawkmoth（Manduca sexta）中分离。其结构特征包括第3位与第9位氨基酸的半胱氨酸残基形成的二硫键，以及羧基末端的氨化。
T85258	Endosulfan II β-Endosulfan,Endosulfan B	Others	Others
	Endosulfan II, an organochlorine insecticide and a stereoisomer of Endosulfan I, effectively targets various insects such as bollworms and tobacco budworms, with lethal doses (LD50s) of 4.14 and 4.95 mg/g, respectively. It interacts with GABA receptors in rat brain membranes, demonstrating an inhibition concentration (IC50) of 60 nM. Notably, Endosulfan II exhibits lower toxicity in rats compared to Endosulfan I, with LD50 values of 240 and 18 mg/kg, respectively.
T62309	Antiviral agent 14	Others	Others
	Antiviral agent 14 是一种抗病毒剂，能够抑制烟草花叶病毒 (TMV) (EC50: 135.5 μg/mL)，和黄瓜花叶病毒 (CMV) (EC50: 178.6 μg/mL)。
T71811	Lobaric acid	Others	Others
	Lobaric acid is a depsidone metabolite that has been isolated from Stereocaulon lichen species with antioxidant, antiproliferative, antiviral, and enzyme inhibitory activites. It scavenges superoxide radicals in a cell-free assay (IC50 = 97.9 μmol) and inhibits proliferation in a panel of leukemia, colorectal, gastric, breast, ovarian, prostate, pancreatic, and lung cancer cell lines (EC50s = 15.2-63.9 μg/ml). Lobaric acid inhibits protein tyrosine phosphatase 1B (PTP1B; IC50 = 0.87 μM for the h...
T79269	TMV-IN-5	Others	Others
	TMV-IN-5（化合物1a）是一种具有抗植物病毒/真菌活性的化合物。该物质能够通过与烟草花叶病毒（TMV）的CP结合，有效抑制病毒组装，有潜力用于农药开发。
T36415	N-Nitroso-N-methyl-4-Aminobutyric Acid	Others	Others
	N-Nitroso-N-methyl-4-aminobutyric acid (NMBA) is a tobacco-specific nitrosamine carcinogen.1It is oxidized to the reactive metabolite methyl-2-oxopropylnitrosamine (MOPN) in isolated rat liver mitochondria.2NMBA induces bladder transitional cell carcinomas in rats when administered in the drinking water at a concentration of 300 mg/L per day.3
T73379	TMV-IN-1	Others	Others
	TMV-IN-1为查尔酮衍生物，兼具烟草花叶病毒(TMV)的抑制作用。该化合物对TMV展现出有效活性，其EC50值为70.7 μg/mL与60.8 μg/mL。TMV-IN-1主要用于感染、炎症和肿瘤相关研究。
T74712	TMV-IN-2	Others	Others
	TMV-IN-2，一种烟草花叶病毒(TMV)抑制剂，属于查尔酮衍生物类别。其对TMV显示出抗病毒活性，其半数有效浓度(EC50)为89.9 μg/mL。该化合物可应用于感染、炎症以及肿瘤的科学研究领域。
T70625	Nicotine lactate	Others	Others
	Nicotine is a naturally produced alkaloid in the nightshade family of plants (most predominantly in tobacco and Duboisia hopwoodii) and is widely used recreationally as a stimulant and anxiolytic. As a pharmaceutical drug, it is used for smoking cessation to relieve withdrawal symptoms. Nicotine acts as a receptor agonist at most nicotinic acetylcholine receptors (nAChRs), except at two nicotinic receptor subunits (nAChRα9 and nAChRα10) where it acts as a receptor antagonist.
T75028	TMV-IN-4	Others	Others
	TMV-IN-4（compound 3）是一种针对烟草花叶病毒（TMV）的抑制剂。该化合物通过与TMV解旋酶交互作用，能够诱导植物产生抗性并提高对TMV感染的耐受性。TMV-IN-4还可增强过氧化物酶和超氧化物歧化酶活性，从而提升烟草的TMV抗性。
T79804	5-HT2 agonist-1	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2 agonist-1 (Compound 24) 是一种选择性5-HT2A, 5-HT2B和5-HT2C激动剂，其IC50值分别为10 nM, 8.3 nM和1.6 nM。5-HT2 agonist-1 free base主要用于研究治疗抑郁症、酗酒、吸烟与可卡因依赖、炎症、丛集性头痛、创伤后应激障碍(PTSD)、癫痫以及其他中枢神经系统疾病。
T79805	5-HT2 agonist-1 free base	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2 agonist-1 (Compound 24) free base 是一种作用于5-HT2A, 5-HT2B和5-HT2C受体的激动剂，其IC50值分别为10 nM, 8.3 nM和1.6 nM。该化合物主要应用于研究抑郁症、酒精依赖、烟草及可卡因成瘾、炎症、丛集性头痛、创伤后应激障碍(PTSD)、癫痫以及其他中枢神经系统相关疾病。
T79806	5-HT2A&5-HT2C agonist-1	5-HT Receptor	GPCR/G Protein; Neuroscience
	5-HT2A&5-HT2C agonist-1 (Example 2) 是一种选择性的5-HT2A和5-HT2C受体激动剂，其IC50值分别为196 nM和0.9 nM。本化合物主要应用于研究抑郁症、酒精依赖、烟草和可卡因成瘾、炎症、丛集性头痛、PTSD、癫痫等中枢神经系统相关疾病。
T69230	AZD-1236	Others	Others
	AZD1236 is a potent and reversible inhibitor of human MMP-9 and MMP-12 (IC50 = 4.5 and 6.1nM, respectively), with >10-fold selectivity to MMP-2 and MMP-13 and >350-fold selectivity to other members of the enzyme family. AZD1236 activity is approximately 20 to 50-fold lower at the rat, mouse, and guinea pig orthologues. In acute models of lung injury, AZD1236 inhibited the haemorrhage and inflammation induced by instillation of human MMP-12 into rat lungs by ~80% at 0.81mg/kg, and also abolished ...
T78135	Nicotelline Nicotellin	Others	Others
	Nicotelline（Nicotellin）是一种与尼古丁相关的生物碱，作为人类cDNA表达的细胞色素P-450 2A6（CYP2A6）的弱抑制剂，不显著抑制该酶介导的香豆素7-羟基化反应，在300 μM浓度下效果更是如此。此外，Nicotelline还被用作烟草烟雾中颗粒物（PM）的示踪剂和生物标记物。
T37202	CC4 CC4	Others	Others
	High affinity and subtype selective α6β2 and α4β2 partial agonist (Ki values are 12 and 26nM for rat α6β2 and α4β2 receptors respectively). Has low affinity for α3β4 and α7 receptors (Ki values are 4.8 and 13 μM for human α3β4 and rat α7 receptors respectively). Stimulates dopamine release from striatal slices in vitro. Attenuates nicotine-induced self-administration and conditional place preference in rats. Sala et al (2013) CC4, a dimer of cytisine, is a selective partial agonist at α4β2/α6β2 ...

化合物

beta-Nicotyrine

Cat.No: T20366

Synonym: bata-碱二烯,Nicotyrine,alpha-Nicotyrine

Target: Others

Cat.No: T27679

Target: AChR

3-Pyridylacetic acid hydrochloride

Cat.No: T1366

Target: DPP-4

Cat.No: T11668

Target: Others

Cat.No: T20533

Synonym: Nicotine-derived nitrosamine ketone

Target: Lipoxygenase

Anatabine dicitrate

Cat.No: T10318

Target: NF-κB

Maleic hydrazide

Cat.No: T20781

Synonym: Antergon,Antyrost,Hydrazide maleique,Burtolin,抑芽丹

Target: Others

N’-Nitrosonornicotine

Cat.No: T36709

Target: Others

Cat.No: T31573

Target: Others

(R,S)-Anatabine (tartrate) (2743-90-0 free base)

Cat.No: T23228

Synonym: (R,S)-Anatabine (tartrate)

Target: Others

Cat.No: T70383

Target: Others

2,5-Deoxyfructosazine (hydrochloride)

Cat.No: T37276

Target: Others

AMPD2 inhibitor 1

Cat.No: T10308

Target: Others

Cat.No: T6060L

Synonym: BB-NC-0036,CCG-38440,H-8174,AR-1H7273,ZX-BK000320,ST-24041653

Target: Others

Cat.No: T79270

Target: Others

Cat.No: T74713

Target: Others

5-methyl Chrysene

Cat.No: T84400

Synonym: NSC 407620

Target: Others

Crustacean cardioactive peptide

Cat.No: T82666

Synonym: CCAP

Cat.No: T85258

Synonym: β-Endosulfan,Endosulfan B

Target: Others

Antiviral agent 14

Cat.No: T62309

Target: Others

Cat.No: T71811

Target: Others

Cat.No: T79269

Target: Others

N-Nitroso-N-methyl-4-Aminobutyric Acid

Cat.No: T36415

Target: Others

Cat.No: T73379

Target: Others

Cat.No: T74712

Target: Others

Nicotine lactate

Cat.No: T70625

Target: Others

Cat.No: T75028

Target: Others

5-HT2 agonist-1

Cat.No: T79804

Target: 5-HT Receptor

5-HT2 agonist-1 free base

Cat.No: T79805

Target: 5-HT Receptor

5-HT2A&5-HT2C agonist-1

Cat.No: T79806

Target: 5-HT Receptor

Cat.No: T69230

Target: Others

Cat.No: T78135

Synonym: Nicotellin

Target: Others

Cat.No: T37202

Synonym: CC4

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T7671	Myosmine 麦司明,麦斯明	Others; AChR	Neuroscience; Others
	Myosmine 是存在于木贼中的一种烟草生物碱，对 a4b2 烟碱乙酰胆碱受体具有低亲和力，Ki 值为 3300 nM。
TN6848	Piperonylic acid 胡椒酸,2H-1,3-benzodioxole-5-carboxylic acid	P450	Metabolism
	Piperonylic acid (2H-1,3-benzodioxole-5-carboxylic acid) 是一种具有亚甲二氧基活性的天然分子，与反式肉桂酸结构相似，可作为选择性反式肉桂酸 4-羟化酶的灭活剂。
T19122	3-Methylvaleric Acid	Others; Endogenous Metabolite	Metabolism; Others
	3-Methylvaleric Acid 是一种食用级香料，存在于烟草中。3-Methylvaleric Acid 可增强 CHO-K1细胞和HEK293细胞中的细胞内cAMP 积累和CRE-荧光素酶活性。
TN1130	Yadanziolide A 鸦胆子素 H,鸦胆子内酯A	Antiviral	Immunology/Inflammation
	Yadanziolide A 来源于 Brucea javanica 干燥的种子。它具有强的抗病毒作用，能够抗烟草花叶病毒(IC50:5.5 μM)。它具有抗肿瘤活性。
T3236	Solanesol Betulanonaprenol,茄尼醇,Nonaisoprenol	Others; Endogenous Metabolite; Antibacterial	Metabolism; Microbiology/Virology; Others
	Solanesol (Betulanonaprenol) 是主要存在于茄科植物中的脂肪族萜烯醇，有抗炎、神经保护和抗菌活性。
T13857	(R,S)-Anatabine	Others; AChR	Neuroscience; Others
	(R,S)-Anatabine 是一种茄科植物中发现的次要烟草生物碱，可用于烟草使用中特定标记物的检测。(R,S)-Anatabine 是α4β2 和 α6/α3β2β4 亚基烟碱乙酰胆碱受体 (nAChRs）激动剂。
T7224	Anabasine (+)-假木贼碱,硫苯咪唑砜,(S)-Anabasine,(-)-Anabasine	AChR	Neuroscience
	Anabasine ((S)-Anabasine) 是一种从烟草中提取的生物碱。Anabasine 是一种烟碱乙酰胆碱受体的全激动剂 (nAChRs)，具有杀虫活性。Anabasine 促使内源表达人肌型 nAChRs 的 TE671 细胞去极化。
T1202	Cotinine (-)-Cotinine,S-(-)-Cotinine,(S)-Cotinine,NIH-10498,可替宁	Endogenous Metabolite; AChR	Metabolism; Neuroscience
	Cotinine (NIH-10498) 是烟草中的生物碱, 也是尼古丁的主要代谢物。Cotinine (NIH-10498) 是测量烟草烟雾成分的生物指标。
T3158	Harmane Loturine,Harman,Aribine,哈尔满碱	Adrenergic Receptor; Monoamine Oxidase; Imidazoline Receptor	GPCR/G Protein; Neuroscience
	Harmane (Loturine) 是一种在咖啡和烟草烟雾中发现的 β-咔啉生物碱，是有效的神经毒素，可引起严重的动作震颤和精神病学表现。它还是选择性的单胺氧化酶抑制剂，具有致突变作用，对 MAO A/B 的 IC50值分别为 0.5 和 5 μM。
T2904	Sclareolide 香紫苏内酯,Norambreinolide	Others; Antibacterial	Microbiology/Virology; Others
	Sclareolide (Norambreinolide) 是一种从Salvia sclarea 的花中分离得到的天然产物，具有抗菌和细胞毒性作用。
T67319	2',4'-Dimethylacetophenone	Endogenous Metabolite	Metabolism
	2',4'-Dimethylacetophenone 是一种可用于生物研究的化学物。该化合物可用于气相色谱法检测烟草化合物中的醛固酮香气，可以用于保护食品。
T35455	N-Nitrosodiethylamine Diethylnitrosamine,NDEA	DNA/RNA Synthesis	Cell Cycle/Checkpoint; DNA Damage/DNA Repair
	N-Nitrosodiethylamine (NDEA) 是致癌物质二烷基硝胺。它主要存在于水、烟草烟雾、腌制食品、油炸食品以及许多酒精饮料中。它与 DNA 修复/复制相关的核酶的变化相关。
TN6395	Citrusin B
	Citrusin B exhibits moderate in vitro inhibitory effect on tobacco mosaic virus replication with IC50 values 0.26 mmol L⁻1.
TN4655	Nicotine 1'-N-oxide	Others	Others
	Nicotine 1'-N-oxide is a natural product from tobacco smoke.
T39918	(±)-Phrymarolin II	Others	Others
	(±)-Phrymarolin II is a promising new class of plant virus (tobacco mosaic virus) inhibitors.
TN1436	Methyl 4-Hydroxyphenylacetate 对羟基苯乙酸甲酯,4-羟基苯乙酸甲酯	Antifection	Microbiology/Virology
	Methyl 4-Hydroxyphenylacetate has potent inhibitory activity against tobacco mosaic virus (TMV).
TN5942	Dammarenediol II 达玛烯二醇II,Dammar-24-ene-3,20-diol
	Dammarenediol II may have the ability to prevent diabetic microvascular complications, including diabetic retinopathy, it can inhibit vascular endothelial growth factor (VEGF)-induced intracellular reactive oxygen species generation and stress fiber forma
T35434	β-Cembrenediol	Others	Others
	β-Cembrenediol (β-CBT) is a natural product from tobacco plants that is found in cigarette smoke condensate. β-CBT inhibits induction of the early antigen of Epstein-Barr virus (EA-EBV) by 12-O-tetradecanoylphorbol-13-acetate (TPA) in vitro (IC50 = 21.9 μM). It inhibits tumor promoting effects of TPA on 7,12-demethylbenz[a]anthracene-induced papilloma formation in vivo. β-CBT is also released into soil by flue-cured tobacco plants and exerts autotoxicity as well as phytotoxic activity against L....
T19128	3-Pyridineacetic acid	Others	Others
	3-Pyridineacetic acid is a homolog of nicotinic acid, a breakdown product of nicotine and other tobacco alkaloids.
T79984	Chaparrinone	Antiviral; Parasite	Immunology/Inflammation; Microbiology/Virology
	Chaparrinone 是一种来自Ailanthus altissima（Mill.）的苦木素类化合物，具有抗疟、抗肿瘤和抗病毒活性，可用于研究烟草花叶病毒感染和SARS 病毒感染。
T79994	7-Deoxy-trans-dihydronarciclasine	Others	Others
	7-Deoxy-trans-dihydronarciclasine 作为生物碱，担任烟草花叶病毒（TMV）抑制剂（IC50: 1.80 μM），亦具有抗神经炎症作用，能够降低Tg2576小鼠大脑皮质中Aβ与APP水平。
T36489	Malformin A	Others	Others
	Malformin A is a cyclopentapeptide fungal metabolite that has been found in A. niger and has diverse biological activities. It is a plant growth regulator that induces malformations in plant structure. Malformin A inhibits replication of tobacco mosaic virus (TMV) in local lesion and leaf-disc assays (IC50s = 19.7 and 45.4 μg/ml, respectively). It is cytotoxic to NCI-H460, MIA PaCa-2, MCF-7, SF-268, and WI-38 cancer cells (IC50s = 70, 50, 100, 70, and 100 nM, respectively), inhibits proliferati...

天然产物

Cat.No: T7671

Synonym: 麦司明,麦斯明

Target: Others, AChR

Piperonylic acid

Cat.No: TN6848

Synonym: 胡椒酸,2H-1,3-benzodioxole-5-carboxylic acid

Target: P450

3-Methylvaleric Acid

Cat.No: T19122

Target: Others, Endogenous Metabolite

Cat.No: TN1130

Synonym: 鸦胆子素 H,鸦胆子内酯A

Target: Antiviral

Cat.No: T3236

Synonym: Betulanonaprenol,茄尼醇,Nonaisoprenol

Target: Others, Endogenous Metabolite, Antibacterial

(R,S)-Anatabine

Cat.No: T13857

Target: Others, AChR

Cat.No: T7224

Synonym: (+)-假木贼碱,硫苯咪唑砜,(S)-Anabasine,(-)-Anabasine

Target: AChR

Cat.No: T1202

Synonym: (-)-Cotinine,S-(-)-Cotinine,(S)-Cotinine,NIH-10498,可替宁

Target: Endogenous Metabolite, AChR

Cat.No: T3158

Synonym: Loturine,Harman,Aribine,哈尔满碱

Target: Adrenergic Receptor, Monoamine Oxidase, Imidazoline Receptor

Cat.No: T2904

Synonym: 香紫苏内酯,Norambreinolide

Target: Others, Antibacterial

2',4'-Dimethylacetophenone

Cat.No: T67319

Target: Endogenous Metabolite

N-Nitrosodiethylamine

Cat.No: T35455

Synonym: Diethylnitrosamine,NDEA

Target: DNA/RNA Synthesis

Cat.No: TN6395

Nicotine 1'-N-oxide

Cat.No: TN4655

Target: Others

(±)-Phrymarolin II

Cat.No: T39918

Target: Others

Methyl 4-Hydroxyphenylacetate

Cat.No: TN1436

Synonym: 对羟基苯乙酸甲酯,4-羟基苯乙酸甲酯

Target: Antifection

Dammarenediol II

Cat.No: TN5942

Synonym: 达玛烯二醇II,Dammar-24-ene-3,20-diol

β-Cembrenediol

Cat.No: T35434

Target: Others

3-Pyridineacetic acid

Cat.No: T19128

Target: Others

Cat.No: T79984

Target: Antiviral, Parasite

7-Deoxy-trans-dihydronarciclasine

Cat.No: T79994

Target: Others

Cat.No: T36489

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-04321	CHRNA5 Protein, Human, Recombinant (His) cholinergic receptor, nicotinic, α5 (neuronal),cholinergic r...	Human	HEK293 Cells
	Genetic variation in the cluster on chromosome 15, encoding the nicotinic acetylcholine receptor subunits (CHRNA5-CHRNA3-CHRNB4), has shown strong associations with tobacco consumption and an additional risk increase in smoking-related diseases such as chronic obstructive pulmonary disease (COPD), peripheral artery disease and lung cancer. CHRNA5 may influence susceptibility to lung cancer among Han smokers. Genetic variation in nicotinic receptor alpha 5 (CHRNA5) has been associated with increa...

重组蛋白

CHRNA5 Protein, Human, Recombinant (His)

Cat.No: TMPY-04321

Species: Human

Expression System: HEK293 Cells

Cat. No.	Product Name	Target	Signaling Pathways
TMIJ-0442	(1'S,2'S)-Nicotine-1'-Oxide-d3
	(1'S,2'S)-Nicotine-1'-Oxide-d3 是 (1'S,2'S)-Nicotine-1'-Oxide 的氘代化合物。(1'S,2'S)-Nicotine-1'-Oxide 的 CAS 号为 51095-86-4。
TMIJ-0438	Myosmine-2,4,5,6-d4
	Myosmine-2,4,5,6-d4 是 Myosmine 的氘代化合物。Myosmine 的 CAS 号为 532-12-7。Myosmine 是存在于木贼中的一种烟草生物碱，对 a4b2 烟碱乙酰胆碱受体具有低亲和力，Ki值为 3300 nM。
TMIJ-0402	N-Nitrosodiethylamine-d10
	N-Nitrosodiethylamine-d10 是 N-Nitrosodiethylamine 的氘代化合物。N-Nitrosodiethylamine 的 CAS 号为 55-18-5。N-Nitrosodiethylamine 是致癌物质二烷基硝胺。它主要存在于水、烟草烟雾、腌制食品、油炸食品以及许多酒精饮料中。它与DNA修复/复制相关的核酶的变化相关。

同位素标记化合物

(1'S,2'S)-Nicotine-1'-Oxide-d3

Cat.No: TMIJ-0442

Myosmine-2,4,5,6-d4

Cat.No: TMIJ-0438

N-Nitrosodiethylamine-d10

Cat.No: TMIJ-0402

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