tetrabenazine-d6

Tetrabenazine D6 is the deuterium-labeled Tetrabenazine. Tetrabenazine is a VMAT-inhibitor used for the treatment of hyperkinetic movement disorder.

Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VMAT2, resulting in decreased uptake

(3R,11bR)-Tetrabenazine-d6 是 (3R,11bR)-Tetrabenazine 的氘代化合物。(3R,11bR)-Tetrabenazine 的 CAS 号为 1026016-83-0。(+)-Tetrabenazine是一种可逆的囊泡单胺转运蛋白2 (VMAT-2)抑制剂，对VMAT2转运的抑制作用是VMAT1的10倍。