n-benzyl-n-bis-peg-4

N-Benzyl-N-bis-PEG4 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Boc-4-pentyne-1-amine 是一种基于烷基链的PROTAC连结剂，用于PROTAC MG-277[1]的合成。

N-Hydroxysulfosuccinimide sodium 是一种不可降解的 ADC 连接剂，用于合成抗体-药物偶联物。

N-piperidine Ibrutinib 是一种有效的 BTK 抑制剂，对 WT BTK 和 C481S BTK 的 IC50 分别为 51.0 和 30.7 nM。它可作为BTK 配体用于一系列PROTAC 的合成，如SJF620。 SJF620 是一种有效的 PROTAC BTK 降解剂，DC50 为 7.9 nM。

BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 是一种基于间苯二酚二Ph醚支架的程序性细胞死亡-1（PD-1） 程序性细胞死亡配体1（PD-L1）抑制剂, 抑制 PD-1 PD-L1 相互作用，IC50 值为 39.2 nM.BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 包含靶蛋白 PD-1 PD-L1 配体和 PROTAC linker。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 可用于合成 PROTAC PD-1 PD-L1 degrader-1。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 具有抗癌活性。BMS-1166-N-piperidine-CO-N-piperazine dihydrochloride 可作为稀释剂，用于用于直接压缩制备片剂。

N-Boc-cis-4-hydroxy-L-proline methyl ester为不可降解(non-cleavable)的ADC linker，用于抗体药物偶联体(ADCs)合成。该化合物同时作为基于烷基链(alkyl chain)的PROTAC linker，适用于PROTAC合成。

N-Boc-PEG5-bromide 是 PROTAC 的 linker，属于 PEG 类和 Alkyl ether 类.它也是可降解的 ADC 连接桥，用于抗体药物结合物的合成。

N-Butanoyl-L-homoserine lactone 是一种可降解的ADClinker，用于抗体偶联药物的合成。它可用于抗菌生物膜，具有抗菌活性。它的适配体抑制铜绿假单胞菌生物膜的形成，可用于阻止群体感应。

Fmoc-N-amido-PEG2-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a polyethylene glycol (PEG)-based linker molecule specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs).

Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a polyethylene glycol-based PROTAC linker employed in PROTAC synthesis.

OICR-9429-N-C2-NH2, a ligand for WDR5, intermediate 2, serves as a crucial compound in the synthesis of PROTACs.

BMS-1166-N-piperidine-COOH is a chemical compound that functions as the BMS-1166-based moiety. It binds to the E3 ligase ligand through a linker, leading to the formation of PROTAC PD-1 PD-L1 degrader-1, which facilitates the degradation of PD-1 PD-L1. BMS-1166 demonstrates potent inhibition of PD-1 PD-L1 interaction, with an IC 50 of 1.4 nM. By antagonizing the inhibitory effect of the PD-1 PD-L1 immune checkpoint on T cell activation, BMS-1166 promotes T cell activation.

N-(Azido-PEG3)-NH-PEG3-acid is a polyethylene glycol (PEG) derived linker utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Amino-PEG4)-N-Biotin-PEG4-acid is a PEG-based PROTAC linker that incorporates biotin for labeling purposes. This compound serves as a versatile tool in the synthesis of PROTACs[1].

THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, facilitates the synthesis of PROTAC K-Ras Degrader-1[1].

N-(Amino-PEG3)-N-bis(PEG3-acid) is a polyethylene glycol (PEG)-based linker compound utilized for synthesizing proteolysis-targeting chimeras (PROTACs)[1].

N-(Ac-PEG3)-N'-(azide-PEG3)-Cy7 (chloride) is a polyethylene glycol (PEG)-based PROTAC linker suitable for synthesizing PROTACs[1].

N-methyl-N'-methyl-O-(m-PEG4)-O'-(azide-PEG4)-Cy5 is a PEG-based linker compound utilized for PROTAC synthesis[1].

N-(Azido-PEG3)-N-Boc-PEG4-acid is a PEG-based PROTAC linker featuring a terminal azide group, primarily employed in PROTAC synthesis[1].

N-(m-PEG9)-N'-(propargyl-PEG8)-Cy5 is a polyethylene glycol (PEG)-based PROTAC linker, specifically designed to aid in the synthesis of PROTACs[1].

N-(Azido-PEG3)-N-Boc-PEG4-Boc is a polyethylene glycol (PEG)-based proteolysis targeting chimeric (PROTAC) linker employed in PROTAC synthesis[1].

N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-derived linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-(m-PEG4)-N'-(m-PEG4)-O-(m-PEG4)-O'-(propargyl-PEG4)-Cy5 serves as a PEG-based PROTAC linker, facilitating the synthesis of PROTACs[1].

N-Mal-N-bis(PEG2-NH-Boc) is a polyethylene glycol (PEG) derived linker specifically designed for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Azido-PEG3)-N-Biotin-PEG4-methyl ester is a polyethylene glycol (PEG) derivative used as a PROTAC linker for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

N-(m-PEG4)-N'-(PEG4-NHS ester)-Cy5 is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-(acid-PEG3)-N-bis(PEG3-azide) is a PEG-based PROTAC linker employed in the synthesis of PROTACs[1].

Fmoc-N-PEG24-acid is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Mal-N-bis(PEG2-amine) is a polyethylene glycol (PEG)-based linker compound commonly employed in the construction of PROTACs, or proteolysis-targeting chimeras[1].

N-Boc-PEG5-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(4-Carboxycyclohexylmethyl)maleimide is an alkyl chain-based PROTAC linker suitable for synthesizing PROTACs[1].

N-Boc-PEG16-alcohol is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-Hydroxypropyl-N’-(azide-PEG3)-Cy3 is a polyethylene glycol (PEG)-based linker specifically designed for use in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Propanoic acid)-N-bis(m-PEG12) is a polyethylene glycol (PEG) based linker for PROTACs synthesis[1].

Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα). Through a linker, Estrone-N-O-C1-amido (ERα ligand 1) forms a complex with the cIAP1 ligand Bestatin, leading to the creation of SNIPER[1].

N-DBCO-N-bis(PEG2-C2-acid) is a polyethylene glycol (PEG) linker commonly employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-Boc-PEG9-alcohol is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].

Mal-N-bis(PEG4-C2-acid) is a polyethylene glycol (PEG) derivative serving as a PEG-based PROTAC linker for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-(NHS-PEG3)-N-bis(PEG3-azide) is a polyethylene glycol (PEG)-based linker commonly utilized for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Boc-PEG2)-N-bis(PEG3-azide) is a polyethylene glycol (PEG)-derived linker used for the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-Boc-N-bis(PEG3-azide) is a polyethylene glycol (PEG) derived linker for the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

N-Me-N-bis-PEG3 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

N-(m-PEG4)-N'-(PEG2-NHS ester)-Cy5 is a polyethylene glycol (PEG) based PROTAC linker utilized for the synthesis of PROTACs[1].

N-(Boc-PEG4)-NH-PEG4-NH-Boc is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker, specifically designed for the synthesis of PROTACs [1].

N-(PEG1-OH)-N-Boc-PEG2-propargyl is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-Boc-N-bis(PEG4-OH) is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

N-Boc-N-bis(PEG2-OH) is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].