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Search Results for " autoinflammatory "

Targets Recommended: STING

5

抑制剂 & 化合物

3

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T5674	H-151	STING	Immunology/Inflammation
	H-151 是一种 STING 拮抗剂，具有高效性和选择性。H-151 与 STING 的 Cys91 共价结合，抑制 Cys91 的棕榈酰化，从而抑制 STING 的活性。H-151 可用于体内外自身炎症性疾病的研究。
T9028	STING-IN-2 C-170	STING	Immunology/Inflammation
	STING-IN-2 (C-170) 是一种 STING 共价抑制剂，可抑制小鼠 STING (mmSTING) 和人类 STING (hsSTING)，可用于自身炎症性疾病的研究。
T76938	Camoteskimab
	Camoteskimab (AVTX-007)为全人源、高亲和力抗IL-18单克隆抗体，展现于自身炎症性疾病研究潜力，包括成人斯蒂尔病(AOSD)。
T12727	RIP2 kinase inhibitor 1	Others	Others
	RIP2 kinase inhibitor 1 is a potent and selective receptor interacting inhibitor of protein 2 (RIP2) kinase(RIP2 FP with an IC50 of 0.03 μM ),and is used for autoinflammatory disorders.
T74572	RIPK2-IN-2	Others	Others
	RIPK2-IN-2 (example 25) 是RIP2 激酶PROTAC 抑制剂。RIPK2-IN-2 可以阻断 RIP2 依赖的促炎信号，调节 RIP2 激酶在自身炎性疾病中的活性。

化合物

Cat.No: T5674

Target: STING

Cat.No: T9028

Synonym: C-170

Target: STING

Cat.No: T76938

RIP2 kinase inhibitor 1

Cat.No: T12727

Target: Others

Cat.No: T74572

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPH-02796	NLRP3 Protein, Mouse, Recombinant (His & SUMO) Nlrp3,Cold autoinflammatory syndrome 1 protein homo...	Mouse	E. coli
	NLRP3 Protein, Mouse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 34.2 kDa and the accession number is Q8R4B8.
TMPH-01739	NLRP3 Protein, Human, Recombinant (His) PYRIN-containing APAF1-like protein 1,Caterpiller protein 1....	Human	E. coli
	NLRP3 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 27.7 kDa and the accession number is Q96P20.
TMPY-06983	IFN gamma Protein, Human, Recombinant (E. coli) Interferon Gamma,IFN γ,IFN gamma,IFG,IFI,干扰素,Interferon γ	Human	E. coli
	IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ...

重组蛋白

NLRP3 Protein, Mouse, Recombinant (His & SUMO)

Cat.No: TMPH-02796

Species: Mouse

Expression System: E. coli

NLRP3 Protein, Human, Recombinant (His)

Cat.No: TMPH-01739

Species: Human

Expression System: E. coli

IFN gamma Protein, Human, Recombinant (E. coli)

Cat.No: TMPY-06983

Species: Human

Expression System: E. coli

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