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Search Results for " allergic conjunctivitis "

Targets Recommended: Histamine Receptor

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Cat. No.	Product Name	Target	Signaling Pathways
T4563	Thonzylamine neohetramine,松齐拉敏	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Thonzylamine (neohetramine) 是可口服的H1组胺受体拮抗剂，具有抗组胺和抗过敏特性，可用于鼻充血、过敏性结膜炎和其他过敏性疾病的研究。
T3979	Emedastine LY188695,依美斯汀,Emadine	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Emedastine (LY188695) 是一种可口服的，选择性和高亲和力的组胺 H1受体拮抗剂，Ki 值为 1.3 nM。它是苯并咪唑衍生物，可用于过敏性鼻炎、过敏性皮肤疾病和过敏性结膜炎的研究。
T21412	Ketorolac Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular	COX	Immunology/Inflammation; Neuroscience
	Ketorolac (Acuvail) 是非甾体抗炎剂，是非选择性的COX 抑制剂，对 COX-1 和 COX-2 的IC50值分别为 20 和 120 nM。
T1269	Tripelennamine hydrochloride Pyribenzamine hydrochloride,去敏灵,Tripelennamine HCl,Pyribenzamine HCl,盐酸曲吡那敏	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Tripelennamine hydrochloride (Pyribenzamine hydrochloride) 是一种组胺 H1 拮抗剂，具有低镇静作用，但经常刺激胃肠道。
T15772	Lodoxamide tromethamine U-42585E	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Lodoxamide tromethamine 是一种的肥大细胞稳定剂，具有抗过敏特性，可用于治疗哮喘和过敏性结膜炎的研究。
T1170	Olopatadine hydrochloride 盐酸奥洛他定,Olopatadine HCl,KW4679,ALO4943A	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Olopatadine hydrochloride (ALO4943A) 是一种抗组胺药，具有稳定肥大细胞的特性，用作治疗过敏性结膜炎的滴眼液。
T6488	Epinastine hydrochloride Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat	5-HT Receptor; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Epinastine hydrochloride (WAL-801CL HCl) 是抗组胺剂和肥大细胞稳定剂，是一种可口服的选择性组胺 H1 受体拮抗剂，可抑制 IL-8 释放，具有抗过敏作用。
T4566	Lodoxamide Lodoxamidum,洛草氨酸	GPR; Histamine Receptor	Endocrinology/Hormones; GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Lodoxamide (Lodoxamidum) 是一种抗过敏药物，作为肥大细胞稳定剂，对治疗哮喘和过敏性结膜炎有效。
T2533	Alcaftadine R89674,Lastacaft,阿卡他定	Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Neuroscience
	Alcaftadine (Lastacaft) 是一种 H1 组胺受体拮抗剂，用于预防与过敏性结膜炎相关的瘙痒。它是一种广谱抗组胺剂，对组胺H1和H2受体具有高亲和力，对H4受体的亲和力较低，还具有调节免疫细胞募集和肥大细胞稳定的作用。
T1278	Astemizole Laridal,Histaminos,Paralergin,阿司咪唑	Potassium Channel; Histamine Receptor	GPCR/G Protein; Immunology/Inflammation; Membrane transporter/Ion channel; Neuroscience
	Astemizole (Laridal) 是一种长效、非镇静抗组胺药，用于治疗季节性过敏性鼻炎、哮喘、过敏性结膜炎和慢性特发性荨麻疹。它是组胺 H1 受体的拮抗剂，IC50值为 4 nM，还阻断 hERG K+通道，IC50值为 0.9 nM，具有抗胆碱能和止痒作用。
T25033	Alcaftadine carboxylic acid	Others	Others
	Alcaftadine is a novel antihistamine for preventing allergic conjunctivitis.
T21388	Emedastine Difumarate Rapimine,DSSTox_CID_26911,AL-3432A,富马酸依美斯汀,KB-2413,Emedastine fumarate,KB 2413	Others	Others
	Emedastine Difumarate is a selective histamine H1 receptor antagonist with anti-allergic activity, prescribed for allergic conjunctivitis. Upon ocular administration, emedastine causes a dose-dependent inhibition of histamine-stimulated vascular permeabil
T0785L	Dexchlorpheniramine free base Polaramine,Dexchlorpheniramine Maleate,Mylaramine	Others	Others
	Dexchlorpheniramine Maleate, a histamine receptor antagonist, is used to treat urticaria, allergic rhinitis, allergic conjunctivitis and pruritus.
T32700	Levocabastine Livostin,Bilina	Others	Others
	Levocarbastine is a second-generation H1 receptor antagonist for allergic conjunctivitis. It also acts as a potent selective antagonist for the neurotensin receptor NTS2 and is the first drug to be used to characterize different neurotensin subtypes.
T21462	Olopatadine Opatanol,Patanol,KW-4943A,KW-4679	Others	Others
	Olopatadine, an antihistamine, as well as anticholinergic and mast cell stabilizer, is used for the treatment of itching associated with allergic conjunctivitis (eye allergies). There is also a potential for Olopatadine to treat steroid rebound (red skin
T21247	Carbinoxamine Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine	Others	Others
	Carbinoxamine, an anticholinergic and antihistamine agent, is used for hay fever, angioedema, vasomotor rhinitis, mild urticaria, dermatographism and allergic conjunctivitis. It is a histamine antagonist, specifically an H1-antagonist.
T60392	Tripelennamine	Others	Others
	Tripelennamine 是一种乙二胺衍生物，是一种有效的组胺 H1受体拮抗剂，可减轻由组织胺引起的机体过敏反应。Tripelennamine 可用于鼻炎、结膜炎、过敏性和过敏性反应的研究。
T62669	Tripelennamine citrate	Others	Others
	Tripelennamine citrate 是一种乙二胺衍生物，是一种有效的组胺 H1 受体拮抗剂。Tripelennamine citrate 能够减少组织胺引起的机体过敏反应。Tripelennamine citrate 能够用于研究鼻炎、结膜炎、过敏性和过敏性反应。
T60590	Chloropyramine	Others	Others
	Chloropyramine 是竞争性可逆 H1 受体拮抗剂，可用于过敏性疾病的研究，例如结膜炎和支气管哮喘。Chloropyramine 表现出抗乳腺癌活性。
T60496	Ketorolac hemicalcium	Others	Others
	Ketorolac (RS37619) hemicalcium 是一种非选择性的 COX 抑制剂，对 COX-1 的 IC50 为 20 nM，对 COX-2 的 IC50 为 120 nM。 Ketorolac hemicalcium 是一种非甾体类抗炎药 (NSAID)，可用作 0.5% 滴眼液，用于研究过敏性结膜炎、黄斑囊样水肿、术中瞳孔缩小和术后眼部炎症和疼痛等。 Ketorolac hemicalcium 也是一种可用于癌症研究的 DDX3 抑制剂 [1] [4]。

化合物

Cat.No: T4563

Synonym: neohetramine,松齐拉敏

Target: Histamine Receptor

Cat.No: T3979

Synonym: LY188695,依美斯汀,Emadine

Target: Histamine Receptor

Cat.No: T21412

Synonym: Toradol,Sprix,Acuvail,Macril,酮咯酸,Acular

Target: COX

Tripelennamine hydrochloride

Cat.No: T1269

Synonym: Pyribenzamine hydrochloride,去敏灵,Tripelennamine HCl,Pyribenzamine HCl,盐酸曲吡那敏

Target: Histamine Receptor

Lodoxamide tromethamine

Cat.No: T15772

Synonym: U-42585E

Target: Histamine Receptor

Olopatadine hydrochloride

Cat.No: T1170

Synonym: 盐酸奥洛他定,Olopatadine HCl,KW4679,ALO4943A

Target: 5-HT Receptor, Histamine Receptor

Epinastine hydrochloride

Cat.No: T6488

Synonym: Alesion,Epinastine HCl,WAL-801CL HCl,依匹斯汀盐酸盐,Elestat

Target: 5-HT Receptor, Histamine Receptor

Cat.No: T4566

Synonym: Lodoxamidum,洛草氨酸

Target: GPR, Histamine Receptor

Cat.No: T2533

Synonym: R89674,Lastacaft,阿卡他定

Target: Histamine Receptor

Cat.No: T1278

Synonym: Laridal,Histaminos,Paralergin,阿司咪唑

Target: Potassium Channel, Histamine Receptor

Alcaftadine carboxylic acid

Cat.No: T25033

Target: Others

Emedastine Difumarate

Cat.No: T21388

Synonym: Rapimine,DSSTox_CID_26911,AL-3432A,富马酸依美斯汀,KB-2413,Emedastine fumarate,KB 2413

Target: Others

Dexchlorpheniramine free base

Cat.No: T0785L

Synonym: Polaramine,Dexchlorpheniramine Maleate,Mylaramine

Target: Others

Cat.No: T32700

Synonym: Livostin,Bilina

Target: Others

Cat.No: T21462

Synonym: Opatanol,Patanol,KW-4943A,KW-4679

Target: Others

Cat.No: T21247

Synonym: Allergefon,(+-)-Carbinoxamine,Paracarbinoxamine

Target: Others

Cat.No: T60392

Target: Others

Tripelennamine citrate

Cat.No: T62669

Target: Others

Cat.No: T60590

Target: Others

Ketorolac hemicalcium

Cat.No: T60496

Target: Others

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