propargyl peg1 acrylate

Propargyl-PEG1-acrylate is a polyethylene glycol (PEG) derived linker employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

(S,R,S)-AHPC-O-PEG1-propargyl 作为一种E3 配体，常用于PROTAC的合成中。此外，它也是一种点击化学试剂，含有 Alkyne 基团，能够通过铜催化的叠氮-炔环加成反应 (CuAAc) 与含 Azide 基团的分子反应。

Propargyl-PEG1-SS-PEG1-acid is a two-unit polyethylene glycol (PEG) linker that is cleavable and commonly employed in the synthesis of antibody-drug conjugates (ADCs) [1].

m-PEG-acrylate (MW 30000) is a polyethylene glycol (PEG)-based bifunctional linker commonly employed in the chemical synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(Amino-PEG1)-N-bis(PEG2-propargyl) HCl salt is a PEG derivative containing an amino group with two propargyl groups. PEG Linkers may be useful in the development of antibody-drug conjugates.

Propargyl-PEG5-1-o-b-cyanoethyl-nn-diisopropylphosphoramidite is a polyethylene glycol (PEG)-based linker molecule specifically designed for the synthesis of proteolysis-targeting chimeras (PROTACs).

Propargyl-PEG3-1-o-b-cyanoethyl-NN-diisopropylphosphoramidite is a polyethylene glycol-based PROTAC linker employed in PROTAC synthesis.

N-(Boc-PEG1)-N-bis(PEG2-propargyl) is a polyethylene glycol (PEG)-derived linker utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Propargyl-PEG1-SS-PEG1-PFP ester is a cleavable linker consisting of a 1-unit polyethylene glycol (PEG) backbone, designed for use in the synthesis of antibody-drug conjugates (ADCs)[1].

Propargyl-PEG1-NHS ester is a non-cleavable 1-unit PEG linker employed in antibody-drug conjugation (ADC) to connect antibodies with drugs.

Propargyl-PEG1-NH2, a PEG-based PROTAC linker, can be utilized in the synthesis of PROTACs[1].

m-PEG-acrylate (MW 2000) is a polyethylene glycol (PEG) derivative linker, which serves as a crucial component in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

N-(PEG1-OH)-N-Boc-PEG2-propargyl is a polyethylene glycol (PEG)-based linker utilized in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Acrylate-PEG-OH (MW 5000) is a Polyethylene Glycol (PEG)-based linker compound primarily utilized in PROTAC synthesis[1].

Bis-propargyl-PEG1 is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Acrylate-PEG-OH (MW 10000) is a Polyethylene Glycol (PEG) derived PROTAC linker utilized for synthesizing PROTACs[1].

N-(Propargyl-PEG4-carbonyl)-N-bis(PEG1-methyl ester) is a polyethylene glycol (PEG) based linker, employed in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].

Propargyl-PEG1-THP is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthetic conjugate compound that combines a Thalidomide-based cereblon ligand and a linker, which is commonly utilized in PROTAC technology. This compound acts as a connector between the target protein and the E3 ligase, facilitating targeted protein degradation.

Acrylate-PEG-NH2 (MW 10000) is a polyethylene glycol (PEG)-based linker utilized in the synthesis of PROTACs[1].

Propargyl-PEG1-acid, a PEG-based PROTAC linker, enables the synthesis of BTK-CRBN PROTACs, specifically Ibrutinib-based PROTAC 4 and PROTAC 5. At a concentration of 10 μM, PROTAC 5 facilitates the degradation of BTK and induces the degradation of CSK, LYN, and LAT2[1].

m-PEG-acrylate (MW 20000), a PEG-based PROTAC linker, serves as a useful component in the synthesis of PROTACs[1].

Propargyl-PEG1-SS-alcohol is a 1-unit PEG ADC linker that is cleavable. It finds application in the synthesis of antibody-drug conjugates (ADCs)[1].

Propargyl-PEG1-SS-PEG1-C2-Boc is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs)[1].

Acrylate-PEG-NH2 (MW 2000) is a polyethylene glycol (PEG)-based PROteolysis TArgeting Chimera (PROTAC) linker, employed for the synthesis of PROTACs [1].

Boc-aminooxy-PEG1-propargyl is a polyethylene glycol (PEG)-based linker commonly employed in the synthesis of proteolysis targeting chimeras (PROTACs)[1].

Propargyl-PEG1-Boc is an alkyl ether-based linker employed for the synthesis of PROTACs[1].

Acrylate-PEG-OH (MW 3400) is a polyethylene glycol (PEG) derived PROTAC linker compound, which finds application in the synthesis of PROTACs[1].

Aminooxy-PEG1-propargyl is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

m-PEG-acrylate (MW 10000) is a polyethylene glycol (PEG)-based linker utilized for the synthesis of Proteolysis Targeting Chimeras (PROTACs)[1].

Propargyl-PEG1-SS-PEG1-propargyl refers to a cleavable di-functional polyethylene glycol (PEG) linker composed of two units. This specific linker is employed in the synthesis of antibody-drug conjugates (ADCs), where it plays a critical role in linking the antibody to the drug. [1]

Thalidomide-O-amido-PEG1-(C1-PEG)2-C2-NH2 is a synthesized conjugate compound known as an E3 ligase ligand-linker. It incorporates a cereblon ligand based on Thalidomide and a 3-unit PEG linker. This compound is specifically designed for use in PROTAC technology applications.