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Cat. No. | Product Name | ||
---|---|---|---|
L9410 | 共价抑制剂库 | 1920 compounds | |
1920 种小分子的独特集合,包含已发现的共价抑制剂以及包含某些共价反应基团常见弹头的分子,如氯乙酰基,2-氯丙酰基,丙烯酰基,1-丙-2-炔基,1-丁-2-炔基,酮羰基,二硫键等,可以用于共价抑制剂药物研发; | |||
DO2200 | 共价抑制剂库CD | 12000 compounds | |
数量多:超过12000种共价结合化合物,并且数量在持续增加; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
C0052 |
Penicillin-Streptomycin-Amphotericin B Solution (100×), Sterile
青霉素-链霉素-两性霉素B三抗溶液(100×),灭菌 |
Solution in bottle |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6436 |
Cefaclor
Panoral,Kefral,Cefaclorum,头孢克洛 |
Others; Antibacterial; Antibiotic | Microbiology/Virology; Others |
Cefaclor (Panoral) 是一种可特异性结合青霉素结合蛋白的抗生素。 | |||
T6231 |
Tebipenem Pivoxil
ME1211,Orapenem,替比培南匹酯 |
Antibacterial; Antibiotic | Microbiology/Virology |
Tebipenem Pivoxil (Orapenem) 是一种碳青霉烯类新型口服抗生素。 | |||
T1495 |
Cefaclor monohydrate
Cefaclor,头孢克洛一水物,头孢克洛一水合物,Cefaclorum,Cefachlor |
Antibacterial; Antibiotic | Microbiology/Virology |
Cefaclor monohydrate (Cefaclorum) 是一种抗生素,可特异性地结合青霉素结合蛋白。 | |||
T21369 |
Mecillinam
Amdinocillin,Mecillinamum,Hexacillin,美西林,Coactin,Penicillin HX |
Antibacterial | Microbiology/Virology |
Mecillinam (Hexacillin) 是一种有抗革兰氏阴性菌活性的 β 内酰胺类广谱抗生素。 | |||
T7733 |
Cefotaxime
|
Anti-infection; Antibacterial; Antibiotic | Microbiology/Virology |
Cefotaxime 是头孢类抗生素和耐内酰胺酶的头孢菌素,具有抗革兰氏阳性菌和革兰氏阴性菌的作用。 | |||
T1005L |
Amoxicillin trihydrate
Amoxycillin trihydrate,Amoxil trihydrate,Amoxipen trihydrate,阿莫西林三水物,Moxaline trihydrate |
Antibacterial; Antibiotic | Microbiology/Virology |
Amoxicillin trihydrate (Moxaline trihydrate) 是一种中谱β内酰胺抗菌素。 | |||
T19643 |
Cefbuperazone Sodium
T 1982,BMY25182,BMY 25182,T-1982,BMY-25182,T1982 |
Others | Others |
Cefbuperazone Sodium is a penicillin-binding protein inhibitor. It is used as antibacterials. | |||
T7723 |
Carumonam Sodium
Ro172301,Ro-17-2301,AMA1080,AMA-1080,Ro 17 2301,AMA 1080 |
Others | Others |
Carumonam Sodium is a monobactam, penicillin-binding protein inhibitor. It is used as antibacterials. | |||
T75288 |
Tebipenem pivoxil hydrochloride
|
Others | Others |
Tebipenem pivoxil (L084) hydrochloride 是具口服活性、对多种致病菌有效的抗生素。通过结合青霉素结合蛋白 (PBP) 抑制细胞壁合成。 | |||
T81157 |
SIGSLAK
|
||
SIGSLAK 拥有与大肠杆菌青霉素结合蛋白 1b (PBP1b) 活性位点相对应的结构特征。 | |||
T37755 |
Phenylacetyl-Coenzyme A (sodium salt)
|
Others | Others |
Phenylacetyl-coenzyme A (CoA) is a key intermediate in aerobic catabolism of phenylacetate in bacteria such asPseudomonas, when cultured in minimal media using phenylacetate as the sole carbon source.1It is a precursor in the synthesis of the antibiotic penicillin G found in industrial strains ofP. chrysogenum. Phenylacetyl-CoA also acts as an effector molecule of the TetR family transcriptional repressor PaaR inT. thermophilusand the GntR family transcriptional regulator PaaX inE. coliandPseudo... | |||
T74866 |
Antibacterial agent 116
|
Others | Others |
Antibacterial agent 116 是一种含二苯甲酮的水杨酰苯胺类化合物。Antibacterial agent 116 能抑制肽聚糖的形成而具有较强的抗菌活性。Antibacterial agent 116 可作为光亲和探针标记 Acinetobacter baumannii 的青霉素结合蛋白 (PBP1b),干扰肽聚糖链的生长,阻断其增殖。 | |||
T71266 |
Omadacycline HCl
|
Others | Others |
Omadacycline, also known as PTK 0796 and Amadacyclin, is a novel first-in-class aminomethylcycline with potent activity against important skin and pneumonia pathogens, including community-acquired methicillin-resistant Staphylococcus aureus (MRSA), β-hemolytic streptococci, penicillin-resistant Streptococcus pneumoniae, Haemophilus influenzae, and Legionella. Omadacycline is active against strains expressing the two main forms of tetracycline resistance (efflux and ribosomal protection). The pri... |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-00169 |
PBP 3 Protein, Bacillus subtilis, Recombinant (His)
Penicillin-binding protein 3,PSPB... |
Bacillus subtilis | E. coli |
Penicillin-binding proteins (PBPs) function in the late steps of murein biosynthesis. Probably required for both cortical and vegetative peptidoglycan synthesis. Although not usually required for cell division, in the absence of PBP 2B (pbpB) it becomes essential. Confers resistance to oxacillin and cephalexin. PBP 3 Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 29.2 kDa and the accession number is P429... | |||
TMPH-00171 |
PBP 4A Protein, Bacillus subtilis, Recombinant (His & SUMO)
PBP 4A,pbpE,Penicillin-binding protein... |
Bacillus subtilis | E. coli |
Probably involved in peptidoglycan modification during cortex synthesis. PBP 4A Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.4 kDa and the accession number is P32959. | |||
TMPH-00170 |
PBP 4 Protein, Bacillus subtilis, Recombinant (His & SUMO)
pbpD,Penicillin-binding protein 4 |
Bacillus subtilis | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits) (Probable). Has a partially redundant function with PBP-2A (pbpA) during spore outgrowth. PBP 4 Protein, Bacillus subtilis, Recombinant (His & SUMO) is expressed in E. coli expression system with N... | |||
TMPH-03044 |
PBP1a Protein, MenB, Recombinant (His & SUMO)
mrcA,Penicillin-binding protein 1... |
MenB | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). | |||
TMPH-00407 |
PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO)
pbpA,Penicillin-binding protein 1... |
Clostridium botulinum | E. coli |
PBP1a Protein, Clostridium botulinum, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-00701 |
PBP1b Protein, E. coli, Recombinant (His & Myc)
Penicillin-binding protein 1B,Mur... |
E. coli | E. coli |
Cell wall formation. Synthesis of cross-linked peptidoglycan from the lipid intermediates. The enzyme has a penicillin-insensitive transglycosylase N-terminal domain (formation of linear glycan strands) and a penicillin-sensitive transpeptidase C-terminal domain (cross-linking of the peptide subunits). PBP1b Protein, E. coli, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 38.6 kDa and the accession number is P02919... |