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Targets Recommended: Antibacterial Antibiotic

抑制剂 & 化合物

天然产物

化合物库

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Cat. No.	Product Name
L3100	造血毒性小分子库	101 compounds
	101 种生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；
L8400	血液病分子库	514 compounds
	514 种造血系统疾病相关的生物活性小分子化合物的特有集合，用于高通量、高内涵筛选；

化合物库

Cat. No.	Product Name	Target	Signaling Pathways
T12004	Meropenem trihydrate 美罗培南三水合物,SM 7338 trihydrate	Antibacterial; Antibiotic	Microbiology/Virology
	Meropenem trihydrate (SM 7338 trihydrate) 是一种碳青霉烯抗生素，具有广谱抗菌活性。它对敏感和耐药的杜克氏杆菌 (MIC 值为 0.015-0.12 mg/mL)，淋病奈瑟氏球菌 (MIC 值为 0.02-0.06 mg/mL)和流感嗜血杆菌 (MIC 值为 0.03-0.12 mg/mL) 具有活性。
T0868L	Cefepime	Others	Others
	Cefepime is an antibiotic. Cefepime has been shown to be effective against febrile neutropenia.
T69516	Thenalidine tartrate	Others	Others
	Thenalidine is an antihistamine with anticholinergic properties used as an antipruritic drug. It was withdrawn from the US, Canadian, and UK markets due to a risk of neutropenia. Thenalidine is an antagonist of the H1-receptor.
T61581	LasR-IN-2	Others	Others
	LasR-IN-2, a compound that inhibits the activity of LasR, forms hydrogen bonding with the TRY-56 residue. It finds application in the study of bacterial infection, neutropenia, severe burns, and chronic lung disease in cystic fibrosis (CF) [1].
T77172	Eflapegrastim
	Eflapegrastim 是一种人源化IgG4单抗，也是一种粒细胞集落刺激因子 (G-CSF)。Eflapegrastim 靶向G-CSF 受体 (c-Fms)。Eflapegrastim 刺激中性粒细胞祖细胞的增殖和分化，维持成熟和功能性中性粒细胞数目稳定。Eflapegrastim 还缩短中性粒细胞减少的持续时间。
T14493	Balapiravir R1626,Ro 4588161	Others	Others
	Balapiravir (R1626, Ro 4588161) is the prodrug of a nucleoside analogue inhibitor of the hepatitis C virus (HCV) RNA-dependent RNA polymerase (R1479, RG1479). IC50 Value: Target: HCV Balapiravir was discontinued for safety reasons in 28-36% of patients (m

化合物

Meropenem trihydrate

Cat.No: T12004

Synonym: 美罗培南三水合物,SM 7338 trihydrate

Target: Antibacterial, Antibiotic

Synonym: R1626,Ro 4588161

Target: Others

Cat. No.	Product Name	Target	Signaling Pathways
T0224	Meropenem 美罗培南,SM 7338	Others; Antibacterial; Antibiotic	Microbiology/Virology; Others
	Meropenem (SM 7338) 是一种具有广谱抗菌活性的碳青霉烯抗生素，对敏感和耐药的淋病奈瑟氏球菌，流感嗜血杆菌和杜克氏杆菌的 MIC 值分别为 0.02-0.06 mg/mL，0.03-0.12 mg/mL 和 0.015-0.12 mg/mL。

天然产物

Meropenem

Cat.No: T0224

Synonym: 美罗培南,SM 7338

Target: Others, Antibacterial, Antibiotic

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Cat. No.	Product Name	Species	Expression System
TMPY-02577	NAMPT Protein, Human, Recombinant (His & GST) VISFATIN,PBEF,PBEF1,1110035O14Rik,VF,nicotinamide phosphorib...	Human	Baculovirus Insect Cells
	Nicotinamide phosphoribosyltransferase (NAMPT), also known as pre-B-cell colony-enhancing factor 1 (PBEF1) or visfatin, is an enzyme belonging to the family of glycosyltransferases, to be specific, the pentosyltransferases. This enzyme participates in nicotinate and nicotinamide metabolism. This enzyme catalyzes the condensation of nicotinamide with 5- phosphoribosyl-1- pyrophosphate to yield nicotinamide mononucleotide, one step in the biosynthesis of nicotinamide adenine dinucleotide. NAMPT is...
TMPJ-00541	CD177 Protein, Human, Recombinant (His) PRV-1,HNA-2a,Human Neutrophil Alloantigen 2a,CD177,Polycythe...	Human	HEK293 Cells
	CD177 is polymorphic and has at least two alleles: PRV1 and NB1. Human PRV1 is a Glycosyl-Phosphatidylinositol (GPI)-linked cell surface glycoprotein that belongs to the uPAR/CD59/Ly6 family of receptors. PRV1 is expressed by neutrophils and neutrophil precursors,and changes in expression serve as diagnostic markers for myeloproliferative disorders such as polycythemia vera and essential thrombocythemia. PRV1 may also be expressed by Erythroblasts, B cells, and Monocytes. NB1, a Glycosyl-Phospha...
TMPY-02252	LAMTOR2 Protein, Human, Recombinant (His) Ragulator2,p14,MAPBPIP,MAPKSP1AP,RP11-336K24.9,HSPC003,late ...	Human	E. coli
	Ragulator complex protein LAMTOR2, also known as Endosomal adaptor protein p14, Late endosomal/lysosomal Mp1-interacting protein, Late endosomal/lysosomal adaptor and MAPK and MTOR activator 2, Mitogen-activated protein-binding protein-interacting protein, Roadblock domain-containing protein 3, LAMTOR2, MAPBPIP, and ROBLD3, is a protein which belongs to the GAMAD family. LAMTOR2 / ROBLD3 is a regulator of the TOR pathway, a signaling cascade that promotes cell growth in response to growth factor...