16
10
58
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T37986 |
D-Mannose-6-Phosphate sodium salt hydrate
|
Others | Others |
D-Mannose-6-Phosphate sodium salt hydrate 是一种多功能单糖,可用于研究代谢、溶酶体传递和癌症。 | |||
T11382 |
GDP-α-D-mannose disodium
|
Others | Others |
GDP-α-D-mannose disodium gives a competitive inhibition with respect to GTP (Ki 14.7 μM) and an uncompetitive inhibition with respect to mannose-1-P (Ki 115 μM).GDP-α-D-mannose disodium is the donor substrate for mannosyltransferases and the precursor of | |||
T14439 | Azido-PEG4-alpha-D-mannose | Others | Others |
Azido-PEG4-alpha-D-mannose is a PEG-based PROTAC linker employed for PROTACs synthesis[1]. | |||
T75247 |
Mannose 1-phosphate
|
Others | Others |
Mannose 1-phosphate,一种内源性代谢物,通过GDP-甘露糖焦磷酸化酶可合成GDP-Man。 | |||
TQ0105 |
CAY10650
|
Phospholipase | Metabolism |
CAY10650 是高效的胞浆磷脂酶A2α抑制剂,IC50=12 nM,能够抑制脂滴形成和 PGE2 分泌。 | |||
T79928 |
Phosphomannose isomerase
|
Others | Others |
Phosphomannose isomerase 是 GDP-Man 生物合成途径中关键的首要酶,负责催化 Fru6P 与 Man6P 之间的互转。该酶对于细胞壁合成及蛋白质糖基化过程至关重要。同时,作为一种潜在的抗真菌靶点,Phosphomannose isomerase 可以有效抑制 A. flavus。 | |||
T81537 |
Paucimannose
|
||
Paucimannose是一种在无脊椎动物和植物中常见的N-糖表位,它的甘露糖苷聚糖形式在癌症中表达。 | |||
T9253 |
CPFX4158
|
Antibacterial | Microbiology/Virology |
CPFX4158 是一种甘露糖衍生物和抗菌剂,可用于转基因人源化 CEACAM6 小鼠。 | |||
T11430 |
Glycosidase-IN-1
|
Others | Others |
Glycosidase-IN-1 is a glycosidase inhibitor synthesized from D-mannose with hypoglycemic activity. It can be used to synthesize some immunosuppressive agents and β-glucosidase inhibitors. | |||
T74537 |
Antifungal agent 26
|
Others | Others |
Antifungal agent 26, a derivative of gramicidin A, exhibits antifungal, antiviral, and antiparasitic activities through binding with polysaccharides containing D-mannose (Man) in pathogens. | |||
T27131 |
DCG04
DCG-04,CD-892,CD 892,DCG 04,CD892 |
Others | Others |
DCG04 is a multivalent ligand for the mannose-6-phosphate receptor. DCG-04 is an activity-based probe for cysteine cathepsins, enabled fluorescent readout of its receptor-targeting properties. DCG04 is used for endolysosomal targeting of an activity-based | |||
T73753 |
Neuraminic acid
|
Others | Others |
Neuraminic acid是由9个碳原子的主链构成的酸性氨基糖,也是丙酮酸与D-甘露胺(2-氨基-2-脱氧甘露糖)醛酸经缩合反应生成的产物。它作为具有生物活性的黏液蛋白的官能团。 | |||
T64537 |
Guanosine 5′-diphospho-β-L-fucose sodium salt
|
Others | Others |
GDP-β-L-fucose is a metabolite in plant and animal. It used for microbe agglutination assay and agglutination inhibition assay. GDP-β-L-fucose is formed by the oxidation-reduction and epimerization of GDP-R-D-mannose in most organisms. | |||
T75412 |
Peptide-N-Glycosidase F (PNGaseF)
|
Others | Others |
Peptide-N-Glycosidase F (PNGaseF) 是一种天冬酰胺酰胺酶。Peptide-N-Glycosidase F 催化来自糖蛋白的高甘露糖、杂合和复杂寡糖的内层 GlcNAc 和天冬酰胺残基之间的 N-连接寡糖裂解。Peptide-N-Glycosidase F 可用于糖蛋白的结构和功能研究。 | |||
T77131 | Clervonafusp alfa | ||
Clervonafusp alfa (VAL-1221) 作为一种融合蛋白,针对胞浆及溶酶体糖原进行靶向。该化合物结合了穿透细胞的抗体Fab部分与重组人酸性葡萄糖苷酶 (rhGAA),通过核苷转运体ENT-2进入细胞质,再利用甘露糖-6-磷酸受体(M6PRs)导向溶酶体。主要应用于晚发型庞贝病的研究领域。 | |||
T83779 |
EP4 Antagonist 14
Prostaglandin E2 Receptor 4 Antagonist 14,PGE2 Receptor 4 Antagonist 14 |
||
EP4 antagonist 14是一种前列腺素E2(PGE2)受体亚型EP4的拮抗剂,其在使用表达人源受体的HEK293细胞的报告基因测定中的IC50值为1.1 nM。它还能抑制PGE2诱导的同种细胞中的β-阿雷斯汀招募(IC50 = 0.9 nM)。EP4 antagonist 14(10 µM)能减少RAW 264.7巨噬细胞中PGE2诱导的mRNA表达,这些mRNA编码Il-4、巨噬细胞甘露糖受体1(Mrc1)、几丁质酶样蛋白3(Chil3)、趋化因子(C-X-C)基序配体1(Cxcl1)、表达在髓样细胞上的触发受体2(Trem2)和精氨酸酶-1(Arg1)。在体内,EP4 antagonist 14(每天30 mg/kg),结合抗PD-1抗体,能够在CT26小鼠结肠癌模型中抑制肿瘤生长并增加CD8+ T细胞对肿瘤的浸润。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T4812 |
D-Mannose
D-(+)-Mannose,D-甘露糖 |
Endogenous Metabolite | Metabolism |
D-Mannose (D-(+)-Mannose) 是糖类,在人体代谢过程,尤其在特定蛋白的糖基化过程中具有重要作用。 | |||
TN6830 |
L-(-)-Mannose
(2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanal |
||
L-(-)-Mannose ((2R,3R,4S,5S)-2,3,4,5,6-pentahydroxyhexanal) 是一种天然存在的非还原糖,常用作食品添加剂。 | |||
T0592 |
D-Mannopyranose
Mannose,D-甘露糖 |
Others | Others |
D-Mannopyranose (Mannose) 是一种己糖或可发酵单糖,是甘露糖、水曲柳和相关植物的葡萄糖异构体。 | |||
T5120 |
Rhamnose
6-Deoxyhexopyranose,L-鼠李糖,6-Deoxy-L-mannose,alpha-L-Rhamnose |
Calcium Channel; Endogenous Metabolite | Membrane transporter/Ion channel; Metabolism |
alpha-L-Rhamnose (6-Deoxy-L-mannose) 是存在植物和细菌中的一种单糖。Rhamnose- 免疫原连接物能被用于免疫疗法。Rhamnose 能通过胞外途径穿过上皮细胞,能够作为肠吸收的标志。 | |||
T2928 |
α-L-Rhamnose monohydrate
L-Rhamnose monohydrate,L-鼠李糖单水合物,6-deoxy-L-mannose monohydrate,α-L-鼠李糖一水合物 |
Others | Others |
α-L-Rhamnose monohydrate (6-deoxy-L-mannose monohydrate) 是植物细胞壁果胶多糖鼠李糖半乳糖醛酸聚糖 1 、鼠李糖半乳糖醛酸聚糖 2 的组分。它也是细菌多糖的组分之一,在致病性方面起重要作用。 | |||
T65209 |
GDP-D-mannose disodium
|
Others | Others |
GDP-D-mannose disodium 是一种天然产物,可用于生命科学领域的相关研究,其产品编号为 T65209。 | |||
T4004 |
Concanavalin A
|
Apoptosis | Apoptosis |
Concanavalin A 是 Ca2+/Mn2+依赖性和甘露糖/葡萄糖结合植物凝集素。它能够促使程序性细胞死亡。 | |||
T8282 |
(S)-(-)-Perillyl alcohol
|
Apoptosis; Ras | Apoptosis; GPCR/G Protein; MAPK |
(S)-(-)-Perillyl alcohol (Perillyl alcohol) 是一种在矮松菊中提取的单萜,具有抗癌活性和神经保护活性,可抑制 Ras 的法尼基化,上调 6-磷酸甘露糖受体并诱导细胞凋亡。 | |||
T4825 |
D-(+)-Xylose
D(+)-Xylose,木糖,(+)-Xylose,Wood sugar |
Endogenous Metabolite | Metabolism |
D-(+)-Xylose (Wood sugar) 是一种是一种戊醛糖,其化学式为C5H10O5,甜度为蔗糖的40%。木糖也存在于结缔组织的粘多糖中,有时也存在于尿液中。 | |||
T20628 | Kifunensine | ||
Kifunensine, a potent and selective inhibitor of class I α-mannosidases, may serve as a key inhibitor of glycoprotein biosynthesis. Its inhibitory effect may lead to high mannose glycoproteins in cell culture. |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03565 |
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant
MBPD,MBP-C,mannose-binding lectin (protein C) 2, so... |
Human | CHO Cells |
Mannan Binding Lectin/MBL2 Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 24 kDa and the accession number is P11226. | |||
TMPJ-00133 |
MBL2 Protein, Mouse, Recombinant
Mannose binding lectin (C),MBL-2,Mannose-b... |
Mouse | HEK293 Cells |
Mannose-binding Lectin (MBL) is an acute phase protein bearing to the family of collectins produced by the liver as a monomer that forms a triple helix. Once released in serum, it further polymerizes forming dimers to octamers. The degree of serum polymerization is critical for the biological activity of MBL. MBL has higher affinity to microbial polysaccharides or their glycoconjugates. MBL was shown earlier to bind cell surfaces of bacteria, fungi, protozoa and viruses and acts as an acute-phas... | |||
TMPY-03473 |
MBL1 Protein, Rat, Recombinant (hFc)
lectin, mannose-binding, 1 |
Rat | HEK293 Cells |
MBL1 Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 50.5 kDa and the accession number is P19999. | |||
TMPY-03057 |
LMAN2L Protein, Human, Recombinant (His)
VIPL,lectin, mannose-binding 2-like |
Human | HEK293 Cells |
LMAN2L Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31.4 kDa and the accession number is Q9H0V9-1. | |||
TMPK-00574 |
MRC2 Protein, Canine, Recombinant (His)
Mannose receptor C type 2 |
Canine | HEK293 Cells |
MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Canine, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.76 kDa and ... | |||
TMPY-03367 |
LMAN2L Protein, Human, Recombinant (hFc)
VIPL,lectin, mannose-binding 2-like |
Human | HEK293 Cells |
LMAN2L Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 56.9 kDa and the accession number is Q9H0V9-1. | |||
TMPJ-00136 |
MBL2 Protein, Human, Recombinant (His)
Collectin-1,Mannose-Binding Lectin,COLEC1,Mannan-Bi... |
Human | HEK293 Cells |
Mannose-Binding Protein C (MBP-C) belongs to the Collectin family of innate immune defense proteins. MBL binds to an array of carbohydrate patterns on pathogen surfaces. Collectin family members share common structural features: a cysteine rich amino-terminal domain, a collagen-like region, an α-helical coiled-coil neck domain and a carboxy terminal C-type Lectin or carbohydrate recognition domain (CRD). MBL homotrimerizes to form a structural unit joined by N-terminal disulfide bridges. These h... | |||
TMPH-00825 |
Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc)
Agglutinin,Mannose-specific lectin,Horcolin |
Domesticated barley | E. coli |
Mannose-specific lectin. Has a weak agglutinating activity against rabbit erythrocytes. Horcolin Protein, Hordeum vulgare subsp. Vulgare, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 22.6 kDa and the accession number is P82953. | |||
TMPH-03442 |
PMT5 Protein, S. cerevisiae, Recombinant (His)
Dolichyl-phosphate-mannose--protein mannosyltransfe... |
Saccharomyces cerevisiae | E. coli |
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT3 and more rarely with PMT2 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. PMT5 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 38.6 kDa and the accession number is P52867. | |||
TMPY-02419 |
LMAN2 Protein, Human, Recombinant (His)
C5orf8,GP36B,lectin, mannose binding 2,VIP36 |
Human | E. coli |
LMAN2 (Lectin, Mannose Binding 2, also known as VIP36) is a Protein Coding gene. This gene encodes a type I transmembrane lectin that shuttles between the endoplasmic reticulum, the Golgi apparatus, and the plasma membrane. The encoded protein binds high mannose type glycoproteins and may facilitate their sorting, trafficking, and quality control. The L-type lectin LMAN2 appears to be specifically required for the accumulation of GPRC5B in the Golgi complex and restriction of GPRC5B transport al... | |||
TMPH-03441 |
PMT3 Protein, S. cerevisiae, Recombinant (His)
Dolichyl-phosphate-mannose--protein mannosyltransfe... |
Saccharomyces cerevisiae | E. coli |
Protein O-mannosyltransferase involved in O-glycosylation which is essential for cell wall rigidity. Forms a heterodimeric complex with PMT5 and more rarely with PMT1 to transfer mannose from Dol-P-mannose to Ser or Thr residues on proteins. Seems to have redundant activity to PMT2. PMT3 Protein, S. cerevisiae, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.6 kDa and the accession number is P47190. | |||
TMPY-00993 |
MBL1 Protein, Mouse, Recombinant (His)
MBP-A,S-MBP,MBL-A,lectin, mannose-binding, 1 |
Mouse | HEK293 Cells |
MBL1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.8 kDa and the accession number is P39039-1. | |||
TMPH-00746 |
FimH Protein, E. coli, Recombinant (His)
Type 1 fimbrin D-mannose specific adhesin,Protein F... |
E. coli | E. coli |
Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | |||
TMPH-01632 |
MRC1 Protein, Human, Recombinant (His)
Human mannose receptor,C-type lectin domain family ... |
Human | E. coli |
Mediates the endocytosis of glycoproteins by macrophages. Binds both sulfated and non-sulfated polysaccharide chains.; (Microbial infection) Acts as phagocytic receptor for bacteria, fungi and other pathogens.; (Microbial infection) Acts as a receptor for Dengue virus envelope protein E.; (Microbial infection) Interacts with Hepatitis B virus envelope protein. MRC1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 69.9... | |||
TMPH-00284 |
MBP-C Protein, Bovine, Recombinant (His)
Mannose-binding protein C,MBL,Mannan-binding protei... |
Bovine | Baculovirus Insect Cells |
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBP-C Protein, Bovine, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 26.9 kDa and the accession... | |||
TMPH-00747 |
FimH Protein, E. coli, Recombinant (Yeast, His)
Type 1 fimbrin D-mannose specific adhesin,Protein F... |
E. coli | P. pastoris (Yeast) |
Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). Adhesin responsible for the binding to D-mannose. It is laterally positioned at intervals in the structure of the type 1 fimbriae. In order to integrate FimH in the fimbriae FimF and FimG are needed. | |||
TMPH-03481 |
FimH Protein, Salmonella typhimurium, Recombinant (His & Myc)
Protein FimH,Type 1 fimbrin D-mannose specific adhe... |
Salmonella typhimurium | E. coli |
Involved in regulation of length and mediation of adhesion of type 1 fimbriae (but not necessary for the production of fimbriae). A mannose-binding adhesin. FimH Protein, Salmonella typhimurium, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 41.2 kDa and the accession number is P37925. | |||
TMPY-04322 |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His)
MBL-C,MBL,mannose-binding lectin (protein C) 2, sol... |
Mouse | HEK293 Cells |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.3 kDa and the accession number is P41317. | |||
TMPY-00429 |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc)
MBL-C,mannose-binding lectin (protein C) 2, soluble... |
Mouse | HEK293 Cells |
Mannan Binding Lectin/MBL2 Protein, Mouse, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 50.6 kDa and the accession number is P41317. | |||
TMPJ-01251 |
POMGNT1 Protein, Human, Recombinant (His)
2-N-Acetylglucosaminyltransferase 1,UDP-GlcNAc:α-D-Mannoside... |
Human | HEK293 Cells |
Protein O-Linked-Mannose β-1 2-N-Acetylglucosaminyltransferase 1 (POMGNT1) belongs to the Glycosyltransferase 13 family. Amino acid residues between 299-311 are important for both protein expression and enzymatic activity. The minimal catalytic domain is located between positions 299-651. It is suggested that the stem domain of the soluble form is unnecessary for activity, but that some amino acids play a crucial role in the membrane-bound form. Defects in POMGNT1 are the cause of muscular dystr... | |||
TMPH-03327 |
MBL2 Protein, Rat, Recombinant (His)
Mannan-binding protein,Ra-reactive factor polysaccharide-bin... |
Rat | E. coli |
Calcium-dependent lectin involved in innate immune defense. Binds mannose, fucose and N-acetylglucosamine on different microorganisms and activates the lectin complement pathway. Binds to late apoptotic cells, as well as to apoptotic blebs and to necrotic cells, but not to early apoptotic cells, facilitating their uptake by macrophages. MBL2 Protein, Rat, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 30.0 kDa and the accession num... | |||
TMPH-01161 |
CLEC18A Protein, Human, Recombinant (His & SUMO)
MRLP2,Mannose receptor-like protein 2,C-type lectin... |
Human | E. coli |
CLEC18A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. | |||
TMPH-03326 |
MASP2 Protein, Rat, Recombinant (His)
Mannan-binding lectin serine protease 2,MBL-associated serin... |
Rat | Baculovirus Insect Cells |
Serum protease that plays an important role in the activation of the complement system via mannose-binding lectin. After activation by auto-catalytic cleavage it cleaves C2 and C4, leading to their activation and to the formation of C3 convertase. MASP2 Protein, Rat, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 79.2 kDa and the accession number is Q9JJS8. | |||
TMPH-01638 |
MASP1 Protein, Human, Recombinant (His & SUMO)
MASP1,Mannose-binding lectin-associated serine prot... |
Human | E. coli |
MASP1 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 93.0 kDa and the accession number is P48740. | |||
TMPK-01225 |
MRC2 Protein, Human, Recombinant (His)
C-type lectin domain family 13 member E, Endocytic receptor ... |
Human | HEK293 Cells |
MRC2 (Mannose Receptor C Type 2) is a constitutively recycling endocytic receptor belonging to the mannose receptor family, which has been found to be closely involved with cancer metastasis. MRC2 expresses an extracellular fibronectin type II domain that binds to and internalizes collagen, suggesting that it may play a role in modulating renal fibrosis. MRC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 57.64 kDa and t... | |||
TMPJ-00980 |
Complement Factor MASP3 Protein, Human, Recombinant (His)
PRSS5,CRARF,Serine Protease 5,MASP1,MASP-1,Mannose-... |
Human | HEK293 Cells |
MASP3 is a member of the MASPs involved in mannan-binding lectin (MBL) complement pathway. The MBL pathway is initiated by the binding of MBL to specific carbohydrate structures found on the surface of a variety of microorganisms. Activation of the complement pathway via MBL is initiated by specific MASPs. Three MASPs have been identified and all have domain structures similar to those of C1r and C1s with a heavy chain (chain A) and a light chain (chain B). Chain A is composed of CUB1, EGF, CUB2... | |||
TMPJ-01111 |
TSTA3 Protein, Human, Recombinant (His)
GDP-L-Fucose Synthase,Short-Chain Dehydrogenase/Reductase Fa... |
Human | E. coli |
GDP-L-Fucose Synthase is a NADP(H)-binding protein. It catalyzes the two-step epimerase and the reductase reactions in GDP-D-mannose metabolism, converting GDP-4-keto-6-D-dexoymannose to GDP-L-fucose. GDP-L-Fucose is the substrate of several fucosyltransferase, involving the expression of mamy glycoconjugates, including blood group ABH antigens and development adhesion antigens. Mutations in the TSTA3 gene may cause leukocyte adhesion deficiency type II. | |||
TMPK-01354 |
IGF2R Protein, Human, Recombinant (His & Avi)
M6P/IGF2R,IGF-II receptor,MPRI,CI-MPR,CD222,MPR 300,M6PR |
Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717. | |||
TMPY-00150 |
IGF2/IGF-II Protein, Human, Recombinant
PP9974,胰岛素样生长因子,C11orf43,IGF-II,insulin-like growth factor 2 |
Human | P. pastoris (Yeast) |
Insulin-like growth factor 2 (IGF-2/IGF-II) is a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumor, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. IGF-2/IGF-II is a mediator of prolactin-induced alveologenesis; prolactin, IGF-2, and cyclin D1, all of which are overexpressed in br... | |||
TMPJ-01257 |
PMM1 Protein, Human, Recombinant (His)
PMMH22,PMM 1,PMMH-22,PMM1,Phosphomannomutase 1 |
Human | E. coli |
Phosphomannomutase 1 (PMM1) blongs to the eukaryotic PMM family. Phosphomannomutase 1 can catalyzes the conversion between D-mannose 6-phosphate and D-mannose 1-phosphate which is a substrate for GDP-mannose synthesis. GDP-mannose is used for synthesis of dolichol-phosphate-mannose which required for a number of critical mannosyl transfer reactions. PMM1 is highly expressed in liver, heart, brain, and pancreas, but lower expression in skeletal muscle. In addition, PMM1 may be responsible for the... | |||
TMPH-03435 |
MNT3 Protein, S. cerevisiae, Recombinant (E. coli, His)
Alpha-1,3-mannosyltransferase MNT3,MNT3 |
Saccharomyces cerevisiae | E. coli |
Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans. MNT3 Protein, S. cerevisiae, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 74.7 kDa and the accession number is P40549. | |||
TMPY-03611 |
PMM2 Protein, Human, Recombinant (His)
CDG1a,phosphomannomutase 2,PMM2,CDGS,CDG1,PMI,PMI1 |
Human | E. coli |
Phosphomannomutase 2, also known as PMM2 and CDG1, belongs to the eukaryotic PMM family. Phosphomannomutase 2 catalyzes the isomerization of mannose 6-phosphate to mannose 1-phosphate. Mannose 1-phosphate is a precursor to GDP-mannose necessary for the synthesis of dolichol-P-oligosaccharides. GDP-mannose can transfer its small sugar molecule called mannose to the growing oligosaccharide chain. Once the correct number of small sugar molecules are linked together to form the oligosaccharide, it c... | |||
TMPH-03058 |
Cyanovirin-N homolog Protein, Neurospora crassa, Recombinant (His)
Cyanovirin-N homolog,CV-N homolog |
Neurospora crassa | E. coli |
Mannose-binding lectin. | |||
TMPH-00363 |
Cyanovirin-N homolog Protein, Ceratopteris richardii, Recombinant (His)
CV-N homolog,Cyanovirin-N homolog |
Ceratopteris richardii | P. pastoris (Yeast) |
Mannose-binding lectin. Cyanovirin-N homolog Protein, Ceratopteris richardii, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 14.4 kDa and the accession number is P86326. | |||
TMPH-03160 |
Glucomannokinase Protein, Prevotella bryantii, Recombinant
Glucomannokinase |
Prevotella bryantii | E. coli |
The enzyme has great affinity for glucose and mannose. Glucomannokinase Protein, Prevotella bryantii, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 2.7 kDa and the accession number is P82680. | |||
TMPH-02610 |
CLEC4G Protein, Mouse, Recombinant (His)
C-type lectin domain family 4 member G,Clec4g |
Mouse | E. coli |
Binds mannose, N-acetylglucosamine (GlcNAc) and fucose, but not galactose, in a Ca(2+)-dependent manner. | |||
TMPH-03063 |
Cyanovirin-N Protein, Nostoc ellipsosporum, Recombinant (His)
CV-N homolog,Cyanovirin-N homolog |
Nostoc ellipsosporum | E. coli |
Mannose-binding lectin. Cyanovirin-N Protein, Nostoc ellipsosporum, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 15.0 kDa and the accession number is P81180. | |||
TMPH-02406 |
Lectin Protein, Lens culinaris, Recombinant (His & Myc)
Lectin |
Lens culinaris | E. coli |
D-mannose specific lectin. Lectin Protein, Lens culinaris, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 27.3 kDa and the accession number is P02870. | |||
TMPH-03436 |
MNT3 Protein, S. cerevisiae, Recombinant (His)
Alpha-1,3-mannosyltransferase MNT3,MNT3 |
Saccharomyces cerevisiae | Baculovirus Insect Cells |
Mannosyltransferase involved in adding the 4th and 5th mannose residues of O-linked glycans. MNT3 Protein, S. cerevisiae, Recombinant (His) is expressed in Baculovirus insect cells with N-10xHis tag. The predicted molecular weight is 71.2 kDa and the accession number is P40549. | |||
TMPH-03198 |
MGAT1 Protein, Rabbit, Recombinant (His & Myc)
MGAT1,Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosa... |
Rabbit | E. coli |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. MGAT1 Protein, Rabbit, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 53.2 kDa and the accession number is P27115. | |||
TMPJ-01303 |
Collectin-11 Protein, Human, Recombinant (His)
Collectin-11,COLEC11,CL-K1,Collectin Kidney Protein 1 |
Human | HEK293 Cells |
Collectin-11 is a secreted protein that belongs to the COLEC10/COLEC11 family. Collectin-11 contains one C-type lectin domain and one collagen-like domain. Collectins play important roles in the innate immune system by binding to carbohydrate antigens on microorganisms, facilitating their recognition and removal. Collectin-11 binds to various sugars including fucose and mannose, but does not bind to glucose, N-acetylglucosamine and N-acetylgalactosamine. It has a higher affinity for fucose compa... | |||
TMPH-00776 |
Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His & Myc)
Griffithsin |
Griffithsia | Baculovirus Insect Cells |
Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells. Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine. | |||
TMPH-00074 |
GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His)
N-acetylglucosaminyltransferase I,Protein COMPLEX GLYCAN LES... |
Arabidopsis thaliana | Baculovirus Insect Cells |
Initiates complex N-linked carbohydrate formation. Essential for the conversion of high-mannose to hybrid and complex N-glycans. Required for normal root growth and morphology. GlcNAcT-I Protein, Arabidopsis thaliana, Recombinant (His) is expressed in Baculovirus insect cells with C-6xHis tag. The predicted molecular weight is 51.6 kDa and the accession number is Q9XGM8. | |||
TMPH-00777 |
Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His)
Griffithsin |
Griffithsia | E. coli |
Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells. Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine. | |||
TMPH-00130 |
Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B Protein, Aspergillus phoenicis, Recombinant (His & Myc)
mns1B,Class I alpha-mannosidase 1B,Mannosyl-oligosaccharide ... |
Aspergillus phoenicis | E. coli |
Involved in the maturation of Asn-linked oligosaccharides. Progressively trims alpha-1,2-linked mannose residues from Man(9)GlcNAc(2) to produce Man(5)GlcNAc(2). Mannosyl-oligosaccharide alpha-1,2-mannosidase 1B Protein, Aspergillus phoenicis, Recombinant (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted molecular weight is 61.3 kDa and the accession number is Q12563. | |||
TMPY-02596 |
GLT25D2 Protein, Human, Recombinant (His)
GLT25D2,RP11-498P10.2,collagen β(1-O)galactosyltransferase 2... |
Human | Baculovirus Insect Cells |
Glycosyl transferase 25 domain 2 (GLT25D2) is a glucosyltransferase enzyme expressed only at low levels in the nervous system. Glycosyltransferases are enzymes that act as a catalyst for the transfer of a monosaccharide unit from an activated nucleotide sugar (also known as the "glycosyl donor") to a glycosyl acceptor molecule, usually an alcohol. Glycosyl transferases transfer glycosyl groups onto their substrate. Localization partially defines their function. Glt25D2 enzyme showed a strong gal... | |||
TMPK-01355 |
IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi)
IGF-II receptor,CI-MPR,CD222,M6P/IGF2R,MPRI,M6PR,MPR 300 |
Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-7 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 117.40 kDa and the accession number is P11717. | |||
TMPJ-01092 |
MGAT2 Protein, Human, Recombinant (His)
Alpha-1,Mannoside Acetylglucosaminyltransferase 2,6-Mannosyl... |
Human | HEK293 Cells |
Mannoside Acetylglucosaminyltransferase 2 (MGAT2) is a single-pass type II membrane protein that contains the typical glycosyltransferase domains: a short N-terminal cytoplasmic domain, a hydrophobic non-cleavable signal-anchor domain and a C-terminal catalytic domain. MGAT2 catalyzes an essential step in the conversion of oligo-mannose to complex N-glycans. Defects in MGAT2 are the cause of congenital disorder of glycosylation type 2A. | |||
TMPK-01353 |
IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi)
CI-MPR,MPR 300,MPRI,M6P/IGF2R,M6PR,CD222,IGF-II receptor |
Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Domain 1-3 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 50.50 kDa and the accession number is P11717. | |||
TMPK-01361 |
IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated
MPR 300,IGF-II receptor,M6PR,M6P/IGF2R,CD222,MPRI,CI-MPR |
Human | HEK293 Cells |
The cation-independent mannose-6-phosphate/insulin-like growth factor 2 receptor (M6P/IGF2R) is a multifunctional receptor. It is involved in a variety of cellular processes which become dysregulated in cancer. IGF2R Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 164.90 kDa and the accession number is P11717. | |||
------------------------ 更多 ------------------------ |