首页 工具
登录
购物车

搜索结果

Search Results for " homology-2 "
Targets Recommended: Tyrosine Kinases JAK

14

抑制剂 & 化合物

1

天然产物

1

化合物库

331

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name
L1710 抗COVID-19化合物库

1133 compounds
1133 种对SARS-CoV-2有抑制作用或潜在抑制作用的化合物集合,可用于高通量和高内涵筛选;

化合物库

抗COVID-19化合物库
Cat.No: L1710
Compounds: 1133
Cat. No. Product Name Target Signaling Pathways
T5049 NVP-BSK805

NVP-BSK805 2HCl,8-[3,5-二氟-4-(4-吗啉基甲基)苯基]-2-[1-(4-哌啶基)-1H-吡唑-4-基]喹喔啉,BSK 805

Tyrosine Kinases; JAK Angiogenesis; Chromatin/Epigenetic; JAK/STAT signaling; Stem Cells; Tyrosine Kinase/Adaptors
NVP-BSK805 (BSK 805) 是 ATP 竞争性的 JAK2抑制剂,对 JAK1 JH1、 JAK2 JH1 (JAK 同源 1)、JAK3 JH1和 TYK2 JH1 的 IC50值分别为 31.63、0.48、8.68 和 10.76 nM。
T23372 SMIFH2

Others Others
SMIFH2 是formin 特异性抑制剂。它利用 Formins 阻碍肌动蛋白聚合,影响肌动蛋白细胞骨架。
T7541 PTP inhibitor 1

PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮

Phosphatase Metabolism
PTP inhibitor 1 是蛋白酪氨酸磷酸酶 (PTP) 抑制剂,具有抗血管生成作用。
T13176 TNO155

Batoprotafib

Phosphatase Metabolism
TNO155 是具有口服活性野生型SHP2的选择性变构抑制剂 (IC50= 0.011 µM)。它有研究 RTK 依赖性恶性肿瘤(尤其是晚期实体瘤)的潜力。
T7084 2-Bromo-4'-hydroxyacetophenone

SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮

Phosphatase Metabolism
2-Bromo-4'-hydroxyacetophenone(PTP Inhibitor I) 是一种PTP1B 的有效抑制剂,其Ki=42 μM。
T14775 Bragsin2

6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2

Others Others
Bragsin2 (6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one) 是非竞争性的核苷酸交换因子 BRAG2选择性抑制剂,其 IC50值为 3 μM。它能够结合到 BRAG2 的 PH 结构域和磷脂双分子层的界面处,使 BRAG2 无法激活磷脂化的 Arf GTPase。它能够影响乳腺癌干细胞。
T38965 EPQpYEEIPIYL

EPQpYEEIPIYL, a phosphopeptide, is a ligand for the Src homology 2 (SH2) domain. It activates members of the Src family, such as Lck, Hck, and Fyn, through the binding interaction with SH2 domains.
T35489 1-O-Octadecyl-2-O-methyl-sn-glycerol

Others Others
1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.
T79186 STAT6-IN-3

STAT JAK/STAT signaling; Stem Cells
STAT6-IN-3 (Compound 18a),一种针对STAT6的Src同源2 (SH2) 结构域的抑制剂,具有44 nM的IC50值。该化合物主要适用于研究哮喘等炎症性疾病。
T27013 CHS-111

CHS 111

Others Others
CHS-111 is a benzyl indazole compound. CHS-111 inhibits superoxide anion (O(2)(-)) generation. CHS-111 reduces the fMLP-stimulated PLD activity (IC(50) 3.9±1.2μM). CHS-111 inhibits the interaction of PLD1 with ADP-ribosylation factor (Arf) 6 and Ras homol
T76356 Neuropeptide Y (2-36) (porcine)

Neuropeptide Y (2-36) (porcine) 是一种具有 97.14% 与大鼠/人类同源性的猪源性神经肽。作为一种大鼠神经肽受体激动剂,其对Y5、Y2和Y1受体的EC50值为1.2, 1.6 和 3.4 nM,能显著增加食物摄入量,适用于肥胖和饮食失调研究。
T76263 Beinaglutide

Beinaglutide 是一种重组人 GLP-1(rhGLP-1) 多肽,与人 GLP-1(7-36) 具有几乎 100% 的同源性。Beinaglutide 在血糖控制、抑制食物摄入和胃排空和促进体重减轻方面表现出依赖于剂量的作用。Beinaglutide 具有研究超重/肥胖和非酒精性脂肪性肝炎 (NASH) 的潜力。
T36939 PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)

Others Others
The phosphatidylinositol (PtdIns) phosphates represent a small percentage of total membrane phospholipids. However, they play a critical role in the generation and transmission of cellular signals. PtdIns-(3,4,5)-P3, also known as PIP3, is resistant to cleavage by PI-specific phospholipase C (PLC). Thus, it is likely to function in signal transduction as a modulator in its own right, rather than as a source of inositol tetraphosphates. PIP3 can serve as an anchor for the binding of signal transd...
T36373 Urocortin II (mouse) (trifluoroacetate salt)

Urocortin II is a neuropeptide hormone and member of the corticotropin-releasing factor (CRF) family which includes mammalian CRF , urocortin , urocortin III , frog sauvagine, and piscine urotensin I.1 Mouse urocortin II shares 34 and 42% sequence homology with rat CRF and urocortin . It is expressed in mouse paraventricular, supraoptic, and arcuate nuclei of the hypothalamus, the locus coeruleus, and in motor nuclei of the brainstem and spinal ventral horn. Urocortin II selectively binds to CRF...

化合物

NVP-BSK805
Cat.No: T5049
Synonym: NVP-BSK805 2HCl,8-[3,5-二氟-4-(4-吗啉基甲基)苯基]-2-[1-(4-哌啶基)-1H-吡唑-4-基]喹喔啉,BSK 805
Target: Tyrosine Kinases, JAK
SMIFH2
Cat.No: T23372
Synonym:
Target: Others
PTP inhibitor 1
Cat.No: T7541
Synonym: PTP Inhibitor II,alpha-溴-4-甲氧基苯乙酮
Target: Phosphatase
TNO155
Cat.No: T13176
Synonym: Batoprotafib
Target: Phosphatase
2-Bromo-4'-hydroxyacetophenone
Cat.No: T7084
Synonym: SHP-1 Inhibitor II,PTP Inhibitor I,α-Bromo-4-hydroxyacetophenone,4-Hydroxyphenacyl bromide,2-溴-4'-羟基苯乙酮
Target: Phosphatase
Bragsin2
Cat.No: T14775
Synonym: 6-methoxy-5-nitro-2-(trifluoromethyl)chromen-4-one,Bragsin 2
Target: Others
EPQpYEEIPIYL
Cat.No: T38965
Synonym:
Target:
1-O-Octadecyl-2-O-methyl-sn-glycerol
Cat.No: T35489
Synonym:
Target: Others
STAT6-IN-3
Cat.No: T79186
Synonym:
Target: STAT
CHS-111
Cat.No: T27013
Synonym: CHS 111
Target: Others
Neuropeptide Y (2-36) (porcine)
Cat.No: T76356
Synonym:
Target:
Beinaglutide
Cat.No: T76263
Synonym:
Target:
PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
Cat.No: T36939
Synonym: PtdIns-(3,4,5)-P3 (1,2-dihexanoyl) (ammonium salt)
Target: Others
Urocortin II (mouse) (trifluoroacetate salt)
Cat.No: T36373
Synonym:
Target:
Cat. No. Product Name Target Signaling Pathways
TN2269 Tetramethylcurcumin

Apoptosis; STAT Apoptosis; JAK/STAT signaling; Stem Cells
Tetramethylcurcumin 是一种新型姜黄素类似物,是一种有效的 STAT3 磷酸化、DNA 结合活性和体外反式激活抑制剂。它具有抗炎和抗癌作用。

天然产物

Tetramethylcurcumin
Cat.No: TN2269
Synonym:
Target: Apoptosis, STAT
Cat. No. Product Name Species Expression System
TMPH-01331 FERMT2 Protein, Human, Recombinant (His)

Kindlin-2,Mitogen-inducible gene 2 protein...

Human E. coli
FERMT2 Protein, Human, Recombinant (His) is expressed in E. coli expression system with C-6xHis tag. The predicted molecular weight is 83.8 kDa and the accession number is Q96AC1.
TMPJ-01156 PHLDA2 Protein, Human, Recombinant (His)

Beckwith-Wiedemann Syndrome Chromosomal Region 1 Candidate G...

Human E. coli
Pleckstrin Homology-Like Domain Family A Member 2 (PHLDA2) is a peripheral membrane protein that belongs to the PHLDA2 family. PHLDA2 is expressed in the placenta and adult prostate gland. In the placenta, it is present in all cells of the villous cytotrophoblast. PHLDA2 plays a role in regulating placenta growth. PHLDA2 may act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids.
TMPK-00383 ACE2/ACEH Protein, Human, Recombinant (His & Avi)

ACE2,ACE-2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPJ-00154 IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)

sIL-15 receptor subunit α,Il15ra,Interleukin-15 receptor sub...

Mouse HEK293 Cells
Mouse interleukin-15 receptor subunit alpha, also known as Il15ra, is a high-affinity receptor for interleukin-15. Il15ra associates as a heterotrimer with the IL-2 receptor beta and gamma subunits (Common gamma chain, or gamma c) to initiate signal transduction. It can signal both in cis and trans where IL15R from one subset of cells presents IL15 to neighboring IL2RG-expressing cells. Il15ra is expressed in special cells including a wide variety of Tand B cells and non-lymphoid cells. Human Il...
TMPY-02700 BCL2 Protein, Human, Recombinant (His)

Bcl-2,PPP1R50,B-cell CLL/lymphoma 2

Human E. coli
BCL2 (B-cell leukemia/lymphoma 2, N-Histidine-tagged), also known as Bcl-2, belongs to the Bcl-2 family. Bcl-2 family proteins regulate and contribute to programmed cell death or apoptosis. It is a large protein family and all members contain at least one of four BH (bcl-2 homology) domains. Certain members such as Bcl-2, Bcl-xl and Mcl1 are anti-apoptotic, whilst others are pro-apoptotic. Most Bcl-2 family members contain a C-terminal transmembrane domain that functions to target these proteins...
TMPJ-01210 IL-33 Protein, Mouse, Recombinant

Interleukin-1 family member 11,白细胞介素,NF-HEV and IL- 1F11,白介素...

Mouse E. coli
Mouse Interleukin 33 (IL-33) is a 30 kDa proinflammatory cytokine which may also regulates gene transcription in producer cells. IL-33 is constitutively expressed in smooth muscle and airway epithelia. IL-33 was identified based on sequence and structural homology with IL-1 family cytokines. It is up‑regulated in arterial smooth muscle, dermal fibroblasts, and keratinocytes following IL-1 alpha or IL‑1 beta stimulation. IL-33 is structurally related to IL-1, which induces helper T cells to produ...
TMPY-01280 FOLR2 Protein, Human, Recombinant (His)

FBP,β-HFR,FR-P3,BETA-HFR,folate receptor 2 (fetal),...

Human HEK293 Cells
Folate receptor beta, also known as Folate receptor 2, FBP, and FOLR2, is a member of the folate receptor family. FOLR2 is expressed in placenta and hematopoietic cells. The expression of FOLR2 is increased in malignant tissues. Members of the Folate receptor family members (FOLRs) have a high affinity for folic acid and for several reduced folic acid derivatives. They mediate the delivery of 5-methyltetrahydrofolate to the interior of, out of within, or between cells in a process known as potoc...
TMPY-02245 SNAP-25 Protein, Human, Recombinant (His)

synaptosomal-associated protein, 25kDa,SEC9,SNAP,RI...

Human E. coli
Synaptosomal-associated protein 25, also known as Super protein, Synaptosomal-associated 25 kDa protein, SNAP25 and SNAP, is a cytoplasm and cell membrane protein that belongs to the SNAP-25 family. SNAP25 / SUP contains 2 t-SNARE coiled-coil homology domains. SNAP25 / SUP is a membrane bound protein anchored to the cytosolic face of membranes via palmitoyl side chains in the middle of the molecule. SNAP25 / SUP protein is a component of the SNARE complex, which is proposed to account for the sp...
TMPY-03974 Bim Protein, Human, Recombinant (His)

BAM,BCL2-like 11 (apoptosis facilitator),BIM,BOD

Human E. coli
BCL2L11, also known as Bim, belongs to the BCL-2 protein family. Members of this family form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BCL2L11 contains a Bcl-2 homology domain 3 (BH3). It has been shown to interact with other members of the BCL-2 protein family, including BCL2, BCL2L1/BCL-X(L), and MCL1, and to act as an apoptotic activator. BCL2L11 gene functions as an essential initiator of apoptosis in thymoc...
TMPJ-01129 SMAD1 Protein, Human, Recombinant (GST)

hSMAD1,Transforming Growth Factor-Beta-Signaling Protein 1,T...

Human E. coli
SMAD Family Member 1 (SMAD1) is a member of the dwarfin/SMAD family. SMAD1 has the highest expression in the heart and skeletal muscle, containing one MAD homology 1 domain and one MAD homology 2 domain, As a transcriptional modulator SMAD 1 is activated by bone morphogenetic proteins type 1 receptor kinase. Defects in SMAD1 may cause primary pulmonary hypertension (PPH1), characterized by plexiform lesions of proliferating endothelial cells in pulmonary arterioles. The lesions lead to elevated ...
TMPJ-01108 SMAD4 Protein, Human, Recombinant (His)

DPC4,SMAD 4,Deletion Target in Pancreatic Carcinoma 4,hSMAD4...

Human E. coli
SMAD Family Member 4 (SMAD4) is a cytoplasmic protein that belongs to the Dwarfin/SMAD family. SMAD4 contains one MH1 (MAD homology 1) domain and one MH2 (MAD homology 2) domain. It is the component of the heterotrimeric SMAD2/SMAD3-SMAD4 complex that forms in the nucleus and is required for the TGF-mediated signaling. SMAD4 promotes binding of the SMAD2/SMAD4/FAST-1 complex to DNA and provides an activation function required for SMAD1 or SMAD2 to stimulate transcription. SMAD4 may act as a tumo...
TMPY-02845 CST9L Protein, Human, Recombinant (hFc)

bA218C14.1,CTES7B,UNQ1835,PRO3543,cystatin 9-like

Human HEK293 Cells
Testatin is a member of the Cystatin family. Cystatins comprise genes that all show expression patterns that are strikingly restricted to reproductive tissue. Cystatins are a family of cysteine protease inhibitors with homology to chicken cystatin. There are typically about 115 amino acids in this family. They are largely acidic, contain four conserved cysteine residues known to form two disulfide bonds, may be glycosylated and/or phosphorylated, with similarity to fetuins, kininogens, stefins, ...
TMPY-03510 Cbl-c Protein, Human, Recombinant (His & GST)

Cbl proto-oncogene C, E3 ubiquitin protein ligase,CBL-SL,CBL...

Human Baculovirus Insect Cells
CBL proteins, such as Cbl-c, are phosphorylated upon activation of a variety of receptors that signal via protein tyrosine kinases. Through interactions with proteins containing SRC homology-2 (SH2) and SH3 domains, CBL proteins modulate downstream cell signaling. Cbl-c is a member of the Cbl family of E3 ubiquitin ligases. Expression of Cbl-c gene may be restricted to epithelial cells, and alternatively spliced transcript variants encoding multiple isoforms have been observed for Cbl-c g...
TMPK-01167 TEM7R/PLXDC2 Protein, Mouse, Recombinant (His)

PLXDC2,TEM7R

Mouse HEK293 Cells
Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plxdc2 is a type I transmembrane protein with some homology to nidogen and to plexins. It is expressed in a highly discrete and dynamic pattern in the developing nervous system, with prominent expression in various patterning centres. TEM7R/PLXDC2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-Hi...
TMPK-01055 TEM7R/PLXDC2 Protein, Human, Recombinant (His)

PLXDC2,TEM7R

Human HEK293 Cells
Plexin domain containing 2 (PLXDC2), a cell surface transmembrane protein receptor for pigment epithelium derived factor, is expressed in many tissues including the eye. Plxdc2 is a type I transmembrane protein with some homology to nidogen and to plexins. It is expressed in a highly discrete and dynamic pattern in the developing nervous system, with prominent expression in various patterning centres. TEM7R/PLXDC2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with C-Hi...
TMPY-03987 T Plastin/PLS3 Protein, Human, Recombinant (His)

BMND18,T-plastin,plastin 3

Human E. coli
PLS3, also known as plastin 3, belongs to the plastin family. Members of this family are actin-binding proteins that are conserved throughout eukaryote evolution and expressed in most tissues of higher eukaryotes. There are two ubiquitous plastin isoforms in humans: L and T. The L isoform is expressed only in hemopoietic cell lineages, while the T isoform has been found in all other normal cells of solid tissues that have replicative potential (fibroblasts, endothelial cells, epithelial cells, m...
TMPK-00382 ACE2/ACEH Protein, Human, Recombinant (hFc & Avi), Biotinylated

ACE-2,ACE2,ACEH

Human HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPK-00552 ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated

ACEH,ACE-2,ACE2

Cynomolgus HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPK-00551 ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi)

ACE-2,ACEH,ACE2

Cynomolgus HEK293 Cells
ACE2 (Angiotensin I Converting Enzyme 2) is a Protein Coding gene. Diseases associated with ACE2 include Severe Acute Respiratory Syndrome and Neurogenic Hypertension.The protein encoded by this gene belongs to the angiotensin-converting enzyme family of dipeptidyl carboxydipeptidases and has considerable homology to human angiotensin 1 converting enzyme. This secreted protein catalyzes the cleavage of angiotensin I into angiotensin 1-9, and angiotensin II into the vasodilator angiotensin 1-7. A...
TMPY-02499 Cofilin 2 Protein, Human, Recombinant (His)

cofilin 2 (muscle),NEM7

Human E. coli
Cofilin 2 (muscle), also known as CFL2, is a member of cofilin family of the actin-binding protein superfamily. Cofilin2 shows significant homology to the other two members: cofilin 1 and DSTN, through its entire sequence, and contains residues conserved among the cofilin family that are responsible for actin-binding. Cofilin 2 (CFL2) is an important regulator of striated myocyte function. Purified cofilin 2 depolymerized actin filaments in a dose- and pH-dependent manner and reduced the apparen...
TMPY-03060 Parvin alpha/PARVA Protein, Human, Recombinant (GST)

parvin, alpha,parvin, α,MXRA2,CH-ILKBP,Parvin α/PAR...

Human E. coli
Actopaxin, also known as alpha-parvin, belongs to the parvin family. It is widely expressed, with highest levels in heart, skeletal muscle, kidney and liver. Actopaxin contains 2 CH (calponin-homology) domains and probably plays a role in the regulation of cell adhesion and cytoskeleton organization. It interacts with integrin-linked protein kinase and probably with actin and the LD1 and LD4 motifs of PXN. Actopaxin binds directly to both F-actin and paxillin LD1 and LD4 motifs. Actopaxin also e...
TMPY-03434 BMF Protein, Human, Recombinant (His)

Bcl2 modifying factor

Human E. coli
BMF(Bcl2 modifying factor) belongs to the BCL2 protein family. BCL2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. BMF contains a single BCL2 homology domain 3 (BH3), and has been shown to bind BCL2 proteins and function as an apoptotic activator. BMF is found to be sequestered to myosin V motors by its association with dynein light chain 2, which may be important for sensing intracellular d...
TMPY-00992 ERAP2 Protein, Human, Recombinant (His)

L-RAP,endoplasmic reticulum aminopeptidase 2,FLJ

Human HEK293 Cells
Leukocyte-derived arginine aminopeptidase (LRAP), also known as endoplasmic reticulum-aminopeptidase 2 (ERAP2), is the second identified aminopeptidase localized in the in the lumenal side of endoplasmic reticulum (ER) processing antigenic peptides presented to major histocompatibility complex (MHC) class I molecules. It is a 96-amino acid protein with significant homology to placental leucine aminopeptidase and adipocyte-derived leucine aminopeptidase. LRAP preferentially hydrolyz...
TMPY-02191 BLNK Protein, Human, Recombinant (His)

BLNK-S,bca,SLP-65,B-cell linker,LY57,SLP65,AGM4,BASH

Human HEK293 Cells
B-cell linker protein, also known as B-cell adapter containing a SH2 domain protein, B-cell adapter containing a Src homology 2 domain protein, Cytoplasmic adapter protein, Src homology 2 domain-containing leukocyte protein of 65 kDa, SLP-65 and BLNK, is a cytoplasm and cell membrane protein which contains oneSH2 domain. BLNK is expressed in B-cell lineage and fibroblast cell lines. Highest levels of expression is in the spleen, with lower levels in the liver, kidney, pancreas, small inte...
TMPJ-00092 CD8 beta Protein, Human, Recombinant (His)

T-Cell Surface Glycoprotein CD8 Beta Chain,CD8B1,CD8B,T-Cell...

Human HEK293 Cells
T-Cell Surface Glycoprotein CD8β Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha a...
TMPY-01100 GPT2 Protein, Rat, Recombinant (His)

glutamic pyruvate transaminase (alanine aminotransferase)

Rat Baculovirus Insect Cells
Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (Gpt), is a pyridoxal enzyme that catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. As a key enzyme for gluconeogenesis, Gpt is a widely-used serum marker for liver injury. Two ALT isoenzymes have been identified, ALT1 and ALT2 (GPT1 and GPT2), which are encoded by separate genes and share ...
TMPY-02440 SAP/SH2D1A Protein, Human, Recombinant (His)

XLPD,EBVS,DSHP,SAP,MTCP1,IMD5,SH2 domain containing...

Human E. coli
SH2domain-containing protein 1A (SH2D1A / SAP) is a 128 amino acid protein, containing a single Src homology 2 (SH2) domain, flanked by 5 amino acids at the N-terminus and 25 amino acids at the C-terminus. The absence of a catalytic domain and the presence of an SH2domain suggest that SH2D1A regulates one or more signal transduction pathways. SH2D1A interacts with signaling lymphocytic activation molecule (SLAM), which is a transmembrane protein expressed on the surface of activated T and B cell...
TMPY-02213 RAIDD Protein, Human, Recombinant (His)

RAIDD,MRT34,CASP2 and RIPK1 domain containing adapt...

Human E. coli
Death domain-containing protein CRADD, also known as Caspase and RIP adapter with death domain, RIP-associated protein with a death domain, CRADD and RAIDD, is a protein which is constitutively expressed in most tissues, with particularly high expression in adult heart, testis, liver, skeletal muscle, fetal liver and kidney. CRADD / RAIDD contains oneCARD domain and onedeath domain. CRADD / RAIDD contains a death domain involved in the binding of RIP protein. The CARD domain mediates the ...
TMPJ-00353 ILDR2 Protein, Human, Recombinant (His)

Angulin-3,immunoglobulin-like domain containing receptor

Human HEK293 Cells
ILDR2 is a member of the B7-like family of proteins that regulate T cell activity, is also a known endoplasmic reticulum molecule that regulates lipid homeostasis. The human ILDR2 lumenal domain shares a 99% and 98% homology with the mouse and rat respectively. The human gene encoding ILDR2 is located in a region on Chr1q23–25 that has been associated with type 2 diabetes. ILDR2 plays critical roles in hepatic clearance of lipoproteins and in lipid homeostasis. ILDR2 regulates human dendritic ce...
TMPY-00894 PAPP-A2 Protein, Human, Recombinant (His)

pappalysin 2,PAPP-E,PLAC3,PAPPE,PAPP-A2

Human HEK293 Cells
Pappalysin-2/PAPP-A2 is the second member of the pappalysin family of metzincin superfamily, of which PAPP-A is the first member. There is no homology between the prepro-peptides of PAPP-A and PAPP-A2, but 46% of the residues of mature PAPP-A are also present in mature PAPP-A2. PAPP-A specifically cleaves insulin-like growth factor-binding protein(IGFBP)-4, one of six known modulators of IGF-I and –II, whereas PAPP-A2 specifically cleaved IGFBP-5 at one site, between Ser-143 and Lys-144. In cont...
TMPY-04402 CSNK1G1 Protein, Human, Recombinant (His & GST)

CK1γ1,casein kinase 1, gamma 1,casein kinase 1, γ1,CK1gamma1

Human Baculovirus Insect Cells
Casein kinase I isoform gamma-1, also known as CSNK1G1, is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family and casein kinase I subfamily. Thecasein kinase I family of protein kinases are serine / threonine-selective enzymes that function as regulators ofsignal transductionpathways in most eukaryotic cell types. Casein has been used as a substrate since the earliest days of research on protein phosphorylation. Casein kinase activity associated with the endopla...
TMPY-01099 GPT Protein, Rat, Recombinant (His)

Gpt1,ALAT,glutamic-pyruvate transaminase (alanine aminotrans...

Rat Baculovirus Insect Cells
Alanine aminotransferase (ALT), also known as glutamate pyruvate transaminase (GPT), is a pyridoxal enzyme that belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family, Alanine aminotransferase subfamily. Gpt / Gpt1 / ALT catalyzes the reversible interconversion of L-alanine and 2-oxoglutalate to pyruvate and L-glutamate and plays a key role in the intermediary metabolism of glucose and amino acids. Gpt / Gpt1 / ALT is expressed in the liver, kidney, heart, and skeletal musc...
TMPY-01831 SLAMF8 Protein, Mouse, Recombinant (His)

Blame,SBBI42,SLAM family member 8,5830408F06Rik

Mouse HEK293 Cells
The signaling lymphocyte activation molecule (SLAM) family includes homophilic and heterophilic receptors that modulate both adaptive and innate immune responses. These receptors share a common ectodomain organization: a membrane-proximal immunoglobulin constant domain and a membrane-distal immunoglobulin variable domain that is responsible for ligand recognition. SLAM family of receptors is expressed by a wide range of immune cells. Through their cytoplasmic domain, SLAM family receptors associ...
TMPY-03220 IZUMO1 Protein, Human, Recombinant (His)

izumo sperm-egg fusion 1,IZUMO

Human HEK293 Cells
Izumo is a sperm membrane protein that plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to now, there four members has an N-terminal domain with significant homology to the N-terminal domain of Izumo. We call this domain the Izumo domain. The four proteins are Izumo 1, 2, 3, and 4. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or t...
TMPY-02889 IZUMO4 Protein, Human, Recombinant (hFc)

C19orf36,IMAGE:4215339,IZUMO family member 4,UNQ831...

Human HEK293 Cells
Izumo is a sperm membrane protein that plays a key role in the fusion in the mouse. It has an Immunoglobulin (Ig) domain and an N-terminal domain for which neither the functions nor homologous sequences are known. Up to now, there four members has an N-terminal domain with significant homology to the N-terminal domain of Izumo. We call this domain the Izumo domain. The four proteins are Izumo 1, 2, 3, and 4. Izumo domain possesses the ability to form dimers, whereas the transmembrane domain or t...
TMPH-01238 POLQ Protein, Human, Recombinant (His)

DNA polymerase eta,POLQ,DNA polymerase theta

Human Baculovirus Insect Cells
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...
TMPY-00891 Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)

neuropilin 1,VEGF165R,CD304,NP1,Neuropilin-1,NRP,BDCA4

Human HEK293 Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 96.5 kDa and the accession number is O14786-2.
TMPY-02096 TACI Protein, Human, Recombinant (His)

RYZN,IGAD2,CVID,TACI,TNFRSF14B,CVID2,tumor...

Human HEK293 Cells
TACI Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 14.8 kDa and the accession number is O14836-2.
TMPY-04113 KRAS Protein,Human,Recombinant(G12D & Q61H, His)

Kirsten rat sarcoma viral oncogene homolog,KRAS2,KI...

Human E. coli
KRAS Protein,Human,Recombinant(G12D & Q61H, His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 23.3 kDa and the accession number is P01116-2.
TMPY-02011 CD96 Protein, Human, Recombinant (His)

CD96 molecule,TACTILE

Human HEK293 Cells
CD96 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55 kDa and the accession number is P40200-2.
TMPY-01442 DMBT1 Protein, Human, Recombinant (His)

GP340,deleted in malignant brain tumors 1,muclin

Human HEK293 Cells
Deleted in malignant brain tumors 1 protein, also known as glycoprotein 34, surfactant pulmonary-associated D-binding protein, DMBT1 and GP34, is a secreted protein which belongs to theDMBT1 family. DMBT1 contains 2CUB domains, 14SRCR domains and 1ZP domain. It is highly expressed in alveolar and macrophage tissues. In some macrophages, expression is detected on the membrane, and in other macrophages, it is strongly expressed in the phagosome/phagolysosome compartments. Defects in DMBT1 are invo...
TMPY-01717 VEGF164 Protein, Mouse, Recombinant

vascular endothelial growth factor A,Vpf,Vegf,血管内皮生长因子

Mouse Baculovirus Insect Cells
VEGF164 Protein, Mouse, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 19.4 kDa and the accession number is Q00731-2.
TMPY-00341 FGFR3 Protein, Human, Recombinant (alpha IIIb, His)

CEK2,HSFGFR3EX,fibroblast growth factor receptor 3,...

Human HEK293 Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40 kDa and the accession number is P22607-2.
TMPY-01613 Periostin/OSF-2 Protein, Mouse, Recombinant (His)

A630052E07Rik,OSF-2,Osf2,PLF,AI74...

Mouse HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 89 kDa and the accession number is Q62009-2.
TMPJ-00850 ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)

Protein T1,suppression of tumorigenicity 2,Ly84,DER...

Mouse HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His) is expressed in HEK293 mammalian cells with C-6xHis tag. The predicted molecular weight is 55-70 KDa and the accession number is P14719-2.
TMPH-01237 POLQ Protein, Human, Recombinant (E. coli, His)

DNA polymerase eta,POLQ,DNA polymerase theta

Human E. coli
DNA polymerase that promotes microhomology-mediated end-joining (MMEJ), an alternative non-homologous end-joining (NHEJ) machinery triggered in response to double-strand breaks in DNA. MMEJ is an error-prone repair pathway that produces deletions of sequences from the strand being repaired and promotes genomic rearrangements, such as telomere fusions, some of them leading to cellular transformation. POLQ acts as an inhibitor of homology-recombination repair (HR) pathway by limiting RAD51 accumul...
TMPY-02217 HSC70 Protein, Human, Recombinant (His)

HSP73,HSC54,HSP71,NIP71,LAP-1,HEL-33,HSPA10,HSC71,LAP1,HEL-S...

Human E. coli
HSPA8, also known as HSC70, is a member of the heat shock protein family due to homology with other heat shock proteins. The heat shock protein 70 family is comprised of both heat-inducible and constitutively expressed members. The latter are called heat-shock cognate proteins. HSPA8 belongs to the heat-shock cognate subgroup. Members of the human heat-shock protein multigene family have several highly conserved proteins with structural and functional properties in common but vary in the extent ...
TMPJ-00521 CHL2 Protein, Mouse, Recombinant (His)

CHRDL2,chordin-like 2,chordin-like protein...

Mouse HEK293 Cells
Mouse Chordin-Like 2, also known as CHL2, is a novel chordin family member with structural homology to CHL1 which is implicated in tumor angiogenesis. The mouse CHL2 gene encodes a 426 amino acids (aa) protein with a 25 aa signal peptide. The mature chain of CHL2 protein contains two potential N-linked glycosylation sites, one putative NLS and three 63 aa cysteine-rich von Willebrand type C repeats (CRs). CHL2 gene is weakly expressed in the liver and kidney, partly expressed in the connective ...
TMPY-01691 Clusterin Protein, Human, Recombinant (CLU34, His)

SGP-2,AAG4,KUB1,CLI,CLU2,TRPM2,AP...

Human HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 51.5 kDa and the accession number is P10909-2.
TMPY-00751 TrkB Protein, Human, Recombinant (His)

trk-B,GP145-TrkB/GP95-TrkB,neurotrophic tyrosine kinase, rec...

Human HEK293 Cells
TrkB Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 45.7 kDa and the accession number is Q16620-2.
------------------------ 更多 ------------------------

重组蛋白

FERMT2 Protein, Human, Recombinant (His)
Cat.No: TMPH-01331
Species: Human
Expression System: E. coli
PHLDA2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01156
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Human, Recombinant (His & Avi)
Cat.No: TMPK-00383
Species: Human
Expression System: HEK293 Cells
IL-15RA Protein, Mouse, Recombinant (hFc, Human Cells)
Cat.No: TMPJ-00154
Species: Mouse
Expression System: HEK293 Cells
BCL2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02700
Species: Human
Expression System: E. coli
IL-33 Protein, Mouse, Recombinant
Cat.No: TMPJ-01210
Species: Mouse
Expression System: E. coli
FOLR2 Protein, Human, Recombinant (His)
Cat.No: TMPY-01280
Species: Human
Expression System: HEK293 Cells
SNAP-25 Protein, Human, Recombinant (His)
Cat.No: TMPY-02245
Species: Human
Expression System: E. coli
Bim Protein, Human, Recombinant (His)
Cat.No: TMPY-03974
Species: Human
Expression System: E. coli
SMAD1 Protein, Human, Recombinant (GST)
Cat.No: TMPJ-01129
Species: Human
Expression System: E. coli
SMAD4 Protein, Human, Recombinant (His)
Cat.No: TMPJ-01108
Species: Human
Expression System: E. coli
CST9L Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02845
Species: Human
Expression System: HEK293 Cells
Cbl-c Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-03510
Species: Human
Expression System: Baculovirus Insect Cells
TEM7R/PLXDC2 Protein, Mouse, Recombinant (His)
Cat.No: TMPK-01167
Species: Mouse
Expression System: HEK293 Cells
TEM7R/PLXDC2 Protein, Human, Recombinant (His)
Cat.No: TMPK-01055
Species: Human
Expression System: HEK293 Cells
T Plastin/PLS3 Protein, Human, Recombinant (His)
Cat.No: TMPY-03987
Species: Human
Expression System: E. coli
ACE2/ACEH Protein, Human, Recombinant (hFc & Avi), Biotinylated
Cat.No: TMPK-00382
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi), Biotinylated
Cat.No: TMPK-00552
Species: Cynomolgus
Expression System: HEK293 Cells
ACE2/ACEH Protein, Cynomolgus, Recombinant (His & Avi)
Cat.No: TMPK-00551
Species: Cynomolgus
Expression System: HEK293 Cells
Cofilin 2 Protein, Human, Recombinant (His)
Cat.No: TMPY-02499
Species: Human
Expression System: E. coli
Parvin alpha/PARVA Protein, Human, Recombinant (GST)
Cat.No: TMPY-03060
Species: Human
Expression System: E. coli
BMF Protein, Human, Recombinant (His)
Cat.No: TMPY-03434
Species: Human
Expression System: E. coli
ERAP2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00992
Species: Human
Expression System: HEK293 Cells
BLNK Protein, Human, Recombinant (His)
Cat.No: TMPY-02191
Species: Human
Expression System: HEK293 Cells
CD8 beta Protein, Human, Recombinant (His)
Cat.No: TMPJ-00092
Species: Human
Expression System: HEK293 Cells
GPT2 Protein, Rat, Recombinant (His)
Cat.No: TMPY-01100
Species: Rat
Expression System: Baculovirus Insect Cells
SAP/SH2D1A Protein, Human, Recombinant (His)
Cat.No: TMPY-02440
Species: Human
Expression System: E. coli
RAIDD Protein, Human, Recombinant (His)
Cat.No: TMPY-02213
Species: Human
Expression System: E. coli
ILDR2 Protein, Human, Recombinant (His)
Cat.No: TMPJ-00353
Species: Human
Expression System: HEK293 Cells
PAPP-A2 Protein, Human, Recombinant (His)
Cat.No: TMPY-00894
Species: Human
Expression System: HEK293 Cells
CSNK1G1 Protein, Human, Recombinant (His & GST)
Cat.No: TMPY-04402
Species: Human
Expression System: Baculovirus Insect Cells
GPT Protein, Rat, Recombinant (His)
Cat.No: TMPY-01099
Species: Rat
Expression System: Baculovirus Insect Cells
SLAMF8 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01831
Species: Mouse
Expression System: HEK293 Cells
IZUMO1 Protein, Human, Recombinant (His)
Cat.No: TMPY-03220
Species: Human
Expression System: HEK293 Cells
IZUMO4 Protein, Human, Recombinant (hFc)
Cat.No: TMPY-02889
Species: Human
Expression System: HEK293 Cells
POLQ Protein, Human, Recombinant (His)
Cat.No: TMPH-01238
Species: Human
Expression System: Baculovirus Insect Cells
Neuropilin-1 Protein, Human, Recombinant (V179A, hFc)
Cat.No: TMPY-00891
Species: Human
Expression System: HEK293 Cells
TACI Protein, Human, Recombinant (His)
Cat.No: TMPY-02096
Species: Human
Expression System: HEK293 Cells
KRAS Protein,Human,Recombinant(G12D & Q61H, His)
Cat.No: TMPY-04113
Species: Human
Expression System: E. coli
CD96 Protein, Human, Recombinant (His)
Cat.No: TMPY-02011
Species: Human
Expression System: HEK293 Cells
DMBT1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01442
Species: Human
Expression System: HEK293 Cells
VEGF164 Protein, Mouse, Recombinant
Cat.No: TMPY-01717
Species: Mouse
Expression System: Baculovirus Insect Cells
FGFR3 Protein, Human, Recombinant (alpha IIIb, His)
Cat.No: TMPY-00341
Species: Human
Expression System: HEK293 Cells
Periostin/OSF-2 Protein, Mouse, Recombinant (His)
Cat.No: TMPY-01613
Species: Mouse
Expression System: HEK293 Cells
ST2/IL-1 RL1 Protein, Mouse, Recombinant (aa 27-337, His)
Cat.No: TMPJ-00850
Species: Mouse
Expression System: HEK293 Cells
POLQ Protein, Human, Recombinant (E. coli, His)
Cat.No: TMPH-01237
Species: Human
Expression System: E. coli
HSC70 Protein, Human, Recombinant (His)
Cat.No: TMPY-02217
Species: Human
Expression System: E. coli
CHL2 Protein, Mouse, Recombinant (His)
Cat.No: TMPJ-00521
Species: Mouse
Expression System: HEK293 Cells
Clusterin Protein, Human, Recombinant (CLU34, His)
Cat.No: TMPY-01691
Species: Human
Expression System: HEK293 Cells
TrkB Protein, Human, Recombinant (His)
Cat.No: TMPY-00751
Species: Human
Expression System: HEK293 Cells
--------- 更多 ---------
TargetMol Loading
联系我们
400-820-0310

上海市静安区江场三路238号8楼