首页工具

登录

搜索结果

Search Results for " gp120 "

Targets Recommended: gp120/CD4 HIV Protease

32

抑制剂 & 化合物

14

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求，可以联系我们专业顾问为您提供针对性的合理建议。 QQ咨询网站留言咨询

Cat. No.	Product Name	Target	Signaling Pathways
T67737	gp120-α4β7 binding inhibitor 11	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	gp120-α4β7 binding inhibitor 11是一种抗HIV 药物。gp120-α4β7 binding inhibitor 11干扰HIV 相关糖蛋白gp12G 与整合素α4β7的结合（IC50=1.64nM）。
T60871	gp120-IN-1	Others	Others
	gp120-IN-1 (compound 4e) 是 HIV-1 gp120蛋白的有效抑制剂，CC50值为 100.90 μM，IC50值为 2.2 μM。gp120-IN-1 抑制 gp120 蛋白介导的病毒进入细胞。gp120-IN-1 具有抗 HIV-1 活性。gp120-IN-1 在 SUP-T1 细胞中具有剂量依赖性细胞毒性。
T60714	gp120-IN-2	Others	Others
	gp120-IN-2 (compound 4i) 显示出抗 HIV-1 活性。它是 HIV-1 gp120的有效抑制剂，IC50值为 7.5 μM，CC50值为 112.93 μM。gp120-IN-2 在癌细胞 SUP-T1 中表现出剂量依赖性的细胞毒性。
T76537	GP120, HIV-1 MN
	GP120，HIV-1MN 是一种肽。GP120,HIV-1MN 可用于 HIV 感染的研究。
T16276	NBD-556	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	NBD-556是一种 CD4 模拟物，识别 HIV-1 包膜蛋白 gp120 并诱导 gp120 重组，类似于 CD4 结合，可阻断 gp120-CD4 的相互作用。
T6418	BMS-378806 BMS378806,BMS-806,1-[(2R)-4-苯甲酰基-2-甲基-1-哌嗪基]-2-(4-甲氧基-1H-吡咯并[2,3-B]吡啶-3-基)-1,2-乙二酮	gp120/CD4; HIV Protease	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	BMS-378806 (BMS-806) 是一种 HIV-1 抑制剂，可选择性抑制 HIV-1 gp120 结合到 CD4 受体，EC50为 0.85-26.5 nM。
TP1785L	Peptide T acetate(106362-32-7 free base)	Others; HIV Protease	Microbiology/Virology; Others; Proteases/Proteasome
	Peptide T acetate(106362-32-7 free base) 是一种来自 HIV-1 gp120 V2 区域的八肽。它是一种合成八肽，其可能的作用机制是 gp120 对 CD4 受体的竞争性抑制以及与血管肠肽受体的结合和抑制细胞因子作用。
T4665	Temsavir BMS626529	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Temsavir (BMS626529) 是一种新型附着抑制剂，靶向 HIV-1 gp120 并阻止其与 CD4+ T 细胞结合。
T71665	INCB-9471	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	INCB-9471 是一种 CCR5 拮抗剂，具有抗HIV活性，抑制 HIV-1 gp120 之间的相互作用。
T10570	Fostemsavir Tris BMS-663068 Tris	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Fostemsavir Tris (BMS-663068 Tris) 是一种 HIV-1附着抑制剂。
T3523	Fostemsavir BMS-663068,磷坦姆沙韦	HIV Protease	Microbiology/Virology; Proteases/Proteasome
	Fostemsavir (BMS-663068) 是 BMS-626529 的原药，可抑制 HIV-1 与细胞 CD4 受体的结合，能结合gp120。
T80580	Zinlirvimab 10-1074
	Zinlirvimab是一种IgG1-λ2类人源化HIV中和抗体，专一性靶向HIV-1 gp120包膜糖蛋白(IIIB gp120 V3环)。
T23108	Ophiobolin C	Others	Others
	inhibitor of human CCR5 binding to HIV-1 gp120
T30532	BMS-585248 CHEMBL236995,CIO2TZZ9H1,BMS 585248,UNII-CIO2TZZ9H1	Others	Others
	BMS-585248 is a highly effective HIV-1 adhesion inhibitor that targets the viral envelope protein gp120.
TP2401	Peptide T amide D-Ala(1)-peptide T amide
	Peptide T amide is an octapeptide segment of HIV envelope gp120 and is used in AIDS therapy.
T72099	Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl
	Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl (化合物 (CPF(LL)) 是一种 HIV-1抑制剂。Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl 能与 gp120相互作用以阻断 gp120与 CD4的结合，并保留 CD4依赖的 T 细胞功能。
T62340	NBD-14189	Others	Others
	NBD-14189 是一种有效的 HIV-1 进入拮抗剂，能够作用于 HIV-1HXB2 假病毒 (IC50: 89 nM)。NBD-14189 能够结合 HIV-1 gp120，并具有显著的抗病毒作用 (EC50<200 nM)。
T69371	BMS 378806	Others	Others
	BMS-378806 is an orally bioavailable HIV-1 inhibitor that interferes with gp120-CD4 interaction.
T71094	CD4 (81-92)	Others	Others
	CD4 (81-92) is a peptide that was previously found to inhibit gp120 binding, HIV-1 infectivity, and syncytium formation.
TP1785	Peptide T
	Peptide T is an octapeptide from the V2 region of HIV-1 gp120. Peptide T is a synthetic octapeptide whose possible mechanism of action is the competitive inhibition of gp120 to the CD4 receptor as well as binding to vasointestinal peptide receptors and in
T81295	Retrocyclin-1
	Retrocyclin-1是一种θ防御素，具有识别并结合含碳水化合物表面分子的能力，能够保护细胞抵御HIV-1感染。该化合物对胎球蛋白、gp120（Kd=35.4 nM）、CD4（Kd=31 nM）以及半乳糖神经酰胺（Kd=24.1 nM）展现出高度亲和性。
T62299	NBD-14270	Others	Others
	NBD-14270 是一种有效的 HIV-1 进入拮抗剂，能够作用于 50 株 HIV-1 假型病毒 (IC50: 89 nM)。NBD-14270 是一种吡啶类似物，细胞毒性低 (CC50>100 μM)。NBD-14270 能够结合 HIV-1 gp120 并表现出显著的抗病毒活性 (EC50<200 nM)。
T68789	N-(3-Phenyl-2-propenyl)-1-deoxynojirimycin	Others	Others
	The effect of N-(3-phenyl-2-propenyl)-1-deoxynojirimycin (ppDNM) on the lectin binding to HIV-1 glycoprotein was analyzed by using biotinylated lectins of various sugar specificities as probes. ppDNM potentially inhibited HIV-1-induced syncytium formation and viral infectivity of HIV-1 without cytotoxicity. The lectin binding assay showed that ppDNM treatment reduced Con A binding to gp120 of HIV-1.
TP1873	Peptide T TFA
	Peptide T (TFA) is an octapeptide derived from the V2 region of HIV-1 gp120. It serves as a ligand for the CD4 receptor, effectively inhibiting the binding of HIV to the CD4 receptor.
T77792	HIV Peptide T	Others	Others
	HIV Peptide T（Peptide T），这种合成的八肽是HIV感染治疗中的一种抗病毒药物，其主要通过竞争性抑制gp120（HIV表面蛋白）与CD4受体的相互作用，同时与血管肠肽（vasointestinal peptide, VIP）受体同源结合并且阻断细胞因子的产生与作用来发挥功效。
TP1910	CALP1
	Cell-permeable calmodulin (CaM) agonist that binds to the EF-hand/Ca2+-binding site; produces CaM-dependent activation of phosphodiesterase. Also binds to cytoplasmic sites on other Ca2+ channels, including NMDA and HIV-1 gp120-activated channels, inhibit
T68842	Complestatin	Others	Others
	Complestatin is a compound extracted from Streptomyces lavendulae mycelia; on acid hydrolysis yields D-4-hydroxyphenylglycine & D-3,5-dichloro-4-hydroxyphenylglycine & acidic chromophore; inhibits gp120-CD4 binding. It is isolated from the culture broth of Streptomyces and has anti-HIV-1 activity. It has a role as a metabolite, an antimicrobial agent and an anti-HIV-1 agent.
T7624	DAPTA DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir	HIV Protease; CCR	Immunology/Inflammation; Microbiology/Virology; Proteases/Proteasome
	DAPTA (Adaptavir) 是一种合成肽，是 CCR5抑制剂，有抗 HIV 的活性。
T37874	Feglymycin
	Feglymycin is a 13-amino acid peptide originally isolated from Streptomyces that has antibacterial and antiviral activities. It is active against Gram-positive bacteria (MICs = 32-64 μg/ml) and inhibits HIV viral replication in H9 cells (IC50 = ~5 μM). Feglymycin is also active against clinical isolates of HIV-1 from clades A-D, A/E, and G (EC50s = 0.5-6.7 μM). It interacts with gp120 and inhibits HIV-1 NL4.3 binding to human soluble CD4 (EC50 = 4.4 μM) and to CD4+ SupT1 T cells by 74.5% when us...
T36185	Globotriaosylceramides (hydroxy) (porcine)	Others	Others
	Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G...
T36186	Globotriaosylceramides (porcine)	Others	Others
	Globotriaosycleramides are glycosphingolipids found in mammalian cell membranes that are synthesized from lactosylceramides . They act as receptors for Shiga and Shiga-like toxins in vitro and in vivo. Globotriaosylceramides accumulate in endothelial cells, pericytes, vascular smooth muscle cells, renal epithelial cells, dorsal ganglia neuronal cells, and myocardial cells in patients with Fabry disease, a lysosomal storage disorder characterized by a deficiency in the enzyme α-galactosidase A. G...
T38103	Defensin HNP-3 (human) (trifluoroacetate salt)
	Defensin HNP-3 is a peptide secreted by human polymorphonuclear leukocytes (PMNs) that has antimicrobial properties. It induces lysis of mammalian cells when used at a concentration of 25 μg/mL. It also inhibits growth of E. faecalis (ED50 = 100 nM) and clinical isolates of P. aeruginosa (MIC90 = 4 μM). HNP-3 binds to recombinant HIV-1 envelope glycoprotein (gp120) and human CD4 (Kds = 52.8 and 34.9 nM, respectively). It also binds to recombinant, immobilized human surfactant protein D (SP-D; Kd...

化合物

gp120-α4β7 binding inhibitor 11

Cat.No: T67737

Target: HIV Protease

Cat.No: T60871

Target: Others

Cat.No: T60714

Target: Others

GP120, HIV-1 MN

Cat.No: T76537

Cat.No: T16276

Target: HIV Protease

Cat.No: T6418

Synonym: BMS378806,BMS-806,1-[(2R)-4-苯甲酰基-2-甲基-1-哌嗪基]-2-(4-甲氧基-1H-吡咯并[2,3-B]吡啶-3-基)-1,2-乙二酮

Target: gp120/CD4, HIV Protease

Peptide T acetate(106362-32-7 free base)

Cat.No: TP1785L

Target: Others, HIV Protease

Cat.No: T4665

Synonym: BMS626529

Target: HIV Protease

Cat.No: T71665

Target: HIV Protease, CCR

Fostemsavir Tris

Cat.No: T10570

Synonym: BMS-663068 Tris

Target: HIV Protease

Cat.No: T3523

Synonym: BMS-663068,磷坦姆沙韦

Target: HIV Protease

Cat.No: T80580

Synonym: 10-1074

Cat.No: T23108

Target: Others

Cat.No: T30532

Synonym: CHEMBL236995,CIO2TZZ9H1,BMS 585248,UNII-CIO2TZZ9H1

Target: Others

Peptide T amide

Cat.No: TP2401

Synonym: D-Ala(1)-peptide T amide

Carbomethoxycarbonyl-D-Pro-D-Phe-OBzl

Cat.No: T72099

Cat.No: T62340

Target: Others

Cat.No: T69371

Target: Others

Cat.No: T71094

Target: Others

Cat.No: TP1785

Cat.No: T81295

Cat.No: T62299

Target: Others

N-(3-Phenyl-2-propenyl)-1-deoxynojirimycin

Cat.No: T68789

Target: Others

Cat.No: TP1873

Cat.No: T77792

Target: Others

Cat.No: TP1910

Cat.No: T68842

Target: Others

Cat.No: T7624

Synonym: DAPTA(TFA),D-Ala-peptide T-amide,Adaptavir

Target: HIV Protease, CCR

Cat.No: T37874

Globotriaosylceramides (hydroxy) (porcine)

Cat.No: T36185

Target: Others

Globotriaosylceramides (porcine)

Cat.No: T36186

Target: Others

Defensin HNP-3 (human) (trifluoroacetate salt)

Cat.No: T38103

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPJ-01313	HIV-1 gp120 Protein (His) Envelope glycoprotein gp120,Surface protei...	HIV	HEK293 Cells
	Envelope glycoprotein gp160 is single-pass type I membrane protein. The mature envelope protein (Env) consists of a homotrimer of non-covalently associated gp120-gp41 heterodimers. It is cleaved into the following 2 chains: glycoprotein 120 and transmembrane protein gp41. The resulting complex protrudes from the virus surface as a spike. The 17 amino acids long immunosuppressive region is present in many retroviral envelope proteins. Synthetic peptides derived from this relatively conserved sequ...
TMPY-01373	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is I6TSC9.
TMPY-00328	Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His) SIV-GP12	SIV	HEK293 Cells
	Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.8 kDa and the accession number is P12492.
TMPY-00331	Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His) SIV-GP12	SIV	HEK293 Cells
	Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.6 kDa and the accession number is D7PU90.
TMPY-04915	HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.8 kDa and the accession number is Q9YUL5.
TMPY-00427	HIV-1 (group P, strain RBF168) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group P, strain RBF168) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 56.2 kDa and the accession number is D0VTQ8.
TMPY-00336	Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His) SIV-GP12	SIV	HEK293 Cells
	Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 60 kDa and the accession number is E2EXP2.
TMPY-01558	HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)	HIV	HEK293 Cells
	HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.4 kDa.
TMPY-00316	HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is Q03805.
TMPY-06486	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated	HIV	HEK293 Cells
	HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 54.8 kDa and the accession number is AFM77980.1.
TMPY-00302	HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 52.2 kDa and the accession number is Q6BC58.
TMPY-00309	HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His)	HIV	HEK293 Cells
	HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 55.4 kDa and the accession number is O11407.
TMPH-00777	Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His) Griffithsin	Griffithsia	E. coli
	Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells. Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine.
TMPH-00776	Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His & Myc) Griffithsin	Griffithsia	Baculovirus Insect Cells
	Mixed specificity lectin with anti-HIV activity. Binds to HIV envelope glycoproteins, including exterior membrane glycoprotein gp120, and inhibits viral entry into cells. Binding to gp120 is dependent on gp120 being glycosylated, and is inhibited by mannose, glucose and N-acetylglucosamine.

重组蛋白

HIV-1 gp120 Protein (His)

Cat.No: TMPJ-01313

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His)

Cat.No: TMPY-01373

Species: HIV

Expression System: HEK293 Cells

Simian immunodeficiency virus (SIV) (isolate F236) gp120 Protein (His)

Cat.No: TMPY-00328

Species: SIV

Expression System: HEK293 Cells

Simian immunodeficiency virus (SIV) (isolate SIVmac251v31523ru28) gp120 Protein (His)

Cat.No: TMPY-00331

Species: SIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype B, Isolate MN) gp120 Protein (His)

Cat.No: TMPY-04915

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group P, strain RBF168) gp120 Protein (His)

Cat.No: TMPY-00427

Species: HIV

Expression System: HEK293 Cells

Simian immunodeficiency virus (SIV) (isolate 216.94.A2) gp120 Protein (His)

Cat.No: TMPY-00336

Species: SIV

Expression System: HEK293 Cells

HIV-1 (group N, strain 06CM-U14296) gp160 (gp120 subunit) Protein (His)

Cat.No: TMPY-01558

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype B, isolate BAL) gp120 Protein (His)

Cat.No: TMPY-00316

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype CRF07_BC) gp120 Protein (His), Biotinylated

Cat.No: TMPY-06486

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype A, isolate 92RW020) gp160 (gp120 subunit) Protein (His)

Cat.No: TMPY-00302

Species: HIV

Expression System: HEK293 Cells

HIV-1 (group M, subtype B, strain SHIV-89.6P) gp120 Protein (His)

Cat.No: TMPY-00309

Species: HIV

Expression System: HEK293 Cells

Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His)

Cat.No: TMPH-00777

Species: Griffithsia

Expression System: E. coli

Griffithsin Protein, Griffithsia sp., Recombinant (X31S, His & Myc)

Cat.No: TMPH-00776

Species: Griffithsia

Expression System: Baculovirus Insect Cells

我们的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。

Copyright © 2015-2024 TargetMol Chemicals Inc. All rights reserved. 沪ICP备20019793号-4

沪公网安备 31010602006700号

沪公网安备 31010602006700号

TargetMol Loading

联系我们

电话：

400-820-0310

邮箱：

service@tsbiochem.com

QQ：

2881945090（终端用户）

2885109491（经销商）

经销：

终端：

地址：

上海市静安区江场三路238号8楼