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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T12909 |
SID 26681509
|
Cysteine Protease; Parasite | Microbiology/Virology; Proteases/Proteasome |
SID 26681509 是可逆的,竞争性的人组织蛋白酶 L 选择性抑制剂,IC50为 56 nM。它抑制Plasmodium falciparum 的体外繁殖,IC50为15.4 μM,抑制Leishmania major,IC5012.5 μM。 | |||
T63831 |
SID 26681509 quarterhydrate
|
Others | Others |
SID 26681509 quarterhydrate 是可逆的、有效的、选择性的、竞争性的人组织蛋白酶 L (human cathepsin L) 抑制剂 (IC50: 56 nM)。SID 26681509 quarterhydrate 能够抑制Plasmodium falciparum 的体外繁殖 (IC50: 15.4 μM),并抑制Leishmania major (IC50: 12.5 μM),且不抑制组织蛋白酶 G 的活性。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04180 |
PfLDH Protein, P. falciparum, Recombinant (His)
PfLDH,L-lactate dehydrogenase |
P. falciparum | E. coli |
Plasmodium falciparum lactate dehydrogenase (PfLDH) is a key enzyme for energy generation of malarial parasites and is considered to be a potential antimalarial target. The ability of PfLDH- or PfIDEh-based immuno-PCR assays to detect <1 parasite/microL suggests that improvements of bound antibody sensor technology may greatly increase the sensitivity of malaria rapid diagnostic tests. The PfLDH test could be used to detect failures and, therefore, to assess anti-malarial efficacy. | |||
TMPH-03143 |
PFD0110w Protein, Plasmodium falciparum, Recombinant
Normocyte-binding protein 1,Reticulocyte-binding protein hom... |
Plasmodium falciparum | E. coli |
PFD0110w Protein, Plasmodium falciparum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 30.1 kDa and the accession number is P86148. | |||
TMPY-04181 |
pfHPRT Protein, P. falciparum, Recombinant (His)
pfHPRT |
P. falciparum | E. coli |
pfHPRT Protein, P. falciparum, Recombinant (His) is expressed in E. coli expression system with His tag. The predicted molecular weight is 28.6 kDa and the accession number is Q76NM3. | |||
TMPH-03142 |
Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc)
PMII,PfAPD,Plasmepsin 2,PfPM1,Aspartic hemoglobinase II,Plas... |
Plasmodium falciparum | E. coli |
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (E. coli, His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. T... | |||
TMPH-03140 |
Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His)
Plasmepsin I,Aspartic hemoglobinase I,Plasmepsin 1,PMI |
Plasmodium falciparum | E. coli |
During the asexual blood stage, catalyzes the initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation; specifically cleaves between Phe-33 and Leu-34 of Hb alpha-chain. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-1 Protein, Plasmodium falciparum, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 41.0 k... | |||
TMPH-03139 |
MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO)
Chloroquine resistance protein,MDR1,Multidrug resistance pro... |
Plasmodium falciparum | E. coli |
Energy-dependent efflux pump responsible for decreased drug accumulation in multidrug-resistant cells. MDR1 Protein, Plasmodium falciparum, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 54.2 kDa and the accession number is P13568. | |||
TMPH-03138 |
GST Protein, Plasmodium falciparum, Recombinant (His)
|
Plasmodium falciparum | P. pastoris (Yeast) |
Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles. May also function as a storage protein or ligandin for parasitotoxic ferriprotoporphyrin IX (hemin). GST Protein, Plasmodium falciparum, Recombinant (His) is expressed in yeast with N-10xHis tag. The predicted molecular weight is 27.3 kDa and the accession number is Q8MU52. | |||
TMPH-03137 |
PFS230 Protein, Plasmodium falciparum, Recombinant
PFS230,Gametocyte surface protein P230 |
Plasmodium falciparum | E. coli |
Gametocyte surface protein required for male/female gamete fusion. Also required for male gamete exflagellation and interaction with erythrocytes. PFS230 Protein, Plasmodium falciparum, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 15.9 kDa and the accession number is P68874. | |||
TMPH-03141 |
Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc)
Plasmepsin II,Aspartic hemoglobinase II,PMII,Plasmepsin 2,Pf... |
Plasmodium falciparum | Baculovirus Insect Cells |
During the asexual blood stage, participates in initial cleavage of native host hemoglobin (Hb) resulting in Hb denaturation. May cleave preferentially denatured hemoglobin that has been cleaved by PMI. Digestion of host Hb is an essential step which provides the parasite with amino acids for protein synthesis, and regulates osmolarity (Probable). Plasmepsin-2 Protein, Plasmodium falciparum, Recombinant (His & Myc) is expressed in Baculovirus insect cells with N-10xHis and C-Myc tag. The predict... |