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Targets Recommended: HSP

抑制剂 & 化合物

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T13554	Arimoclomol maleate BRX-220	HSP	Cytoskeletal Signaling; Metabolism
	Arimoclomol maleate (BRX-220) 是一种热休克蛋白 (HSP) 的共诱导剂。它通过增强 Hsp 表达来保护运动神经元，进而通过蛋白酶体-泛素系统直接影响蛋白质聚集和错误折叠装配体的清除
T13553	Arimoclomol 阿瑞洛莫,BRX-220 free base	HSP	Cytoskeletal Signaling; Metabolism
	Arimoclomol (BRX-220 free base) 是热休克蛋白 (HSP) 的共诱导剂，可用于治疗肌萎缩侧索硬化症的研究。
T40468	Arimoclomol citrate Arimoclomol citrate,BRX-220 citrate	Others	Others
	Arimoclomol citrate (BRX-220 citrate) is a heat shock protein (HSP) co-inducer that acts by enhancing Hsp expression and directly impacting protein aggregation, clearance of misfolded assemblies, and the proteasome-ubiquitin system. This compound is known for its ability to protect motor neurons.
T36470	Biotinyl hexylamine	Others	Others
	Biotinyl hexylamine is a synthetic intermediate.1,2It has been used in the synthesis of avidin nucleic acid nano assemblies (ANANAS) and chemotherapeutic conjugates for the diagnosis of, and drug delivery to, tumors. 1.Sabatino, G., Chinol, M., Paganelli, G., et al.A new biotin derivative-DOTA conjugate as a candidate for pretargeted diagnosis and therapy of tumorsJ. Med. Chem.46(14)3170-3173(2003) 2.Bigini, P., Previdi, S., Casarin, E., et al.In vivo fate of avidin-nucleic acid nanoassemblies a...
T82574	DFAME
	DFAME为一种帶有红色荧光的基团（Ex=508 nm，Em=641 nm）。它能与二聚体荧光RNA适体Beetroot及Corn结合，分别形成Beetroot-DFAME复合体（Kd=460 nM）和Corn-DFAME复合体（Kd=3600 nM）。这两种复合体可应用于细胞内RNA组装体的形成，利用RNA结构的自组装特性研究RNA纳米结构。
T37218	N-methyl Mesoporphyrin IX
	N-methyl Mesoporphyrin IX 是广泛使用的 G-quadruplex DNA 特异性荧光结合剂，能有效监测 Aβ 纤颤。N-methyl Mesoporphyrin IX 对 G-四链体 DNA 敏感，对双链体、三链体和单链形式的 DNA 没有反应。N-methyl Mesoporphyrin IX 需通过与 Aβ 组装体堆叠才能发出强荧光。同时 N-methyl Mesoporphyrin IX 是一种原位抑制剂，是体外和细胞内 Aβ 淀粉样蛋白生成的非原位监测器。

化合物

Synonym: 阿瑞洛莫,BRX-220 free base

Target: HSP

Arimoclomol citrate

Cat.No: T40468

Synonym: Arimoclomol citrate,BRX-220 citrate

N-methyl Mesoporphyrin IX

Cat.No: T37218

Synonym:

Target:

Species：

Expression System：

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Cat. No.	Product Name	Species	Expression System
TMPK-01413	H-2K (b) &B2M&OVA (SIINFEKL) Monomer Protein, Mouse, MHC (His & Avi) H-2K,OVA,MHC,H2-K1	Mouse	HEK293 Cells
	Ovalbumin (OVA) has been historically a popular source of such antigens, since OVA can induce both humoral and cellular immune responses based on well-characterised peptide epitopes. The OVA257-264 octapeptide was one of the frst OVA epitopes to be characterised, it has an amino acid sequence SIINFEKL, which is recognised by cytotoxic T lymphocytes. SIINFEKL forms fbrillar assemblies similar to other peptide hydrogels. Te immunoactive properties of this peptide can therefore be related to its se...