mfz 10 7 hydrochloride

MFZ 10-7 hydrochloride is a highly potent and selective negative allosteric modulator of mGluR5 NAM

NLX-204 hydrochloride（2170405-10-2 free base）是一种有效且选择性的 ERK1/2 磷酸化偏好 5-HT1A 受体激动剂 (pKi = 10.19)。

UNC0064-12 hydrochloride (1430089-64-7(free base)) 是一种VEGFR2 抑制剂。

Betrixaban hydrochloride(330942-05-7(free base)) (PRT054021 hydrochloride) 是一种有效的、选择性的、口服有效的 Xa 因子 (fXa) 抑制剂 (IC50: 1.5 nM)。

ML-7 hydrochloride (ML-7 HCl) 是一种可渗透细胞的、可逆的、有效的、ATP 竞争性的肌球蛋白轻链激酶(MLCK) 特异性抑制剂，IC50为300 nM。它还抑制平滑肌肌球蛋白轻链激酶、PKA 和 PKC。

JMV 2959 hydrochloride (925238-89-7 free base) 是一种生长激素促分泌素受体 1a 型 (GHS-R1a) 拮抗剂，在 LLC-PK1 细胞中的 IC50 为 32±3 nM。

MFZ 10-7 是 mGluR5 的负变构调节剂。

rac-7-hydroxy Propranolol (hydrochloride) is a ring-hydroxylated isomer and metabolite of propranolol that is an antagonist at β-adrenergic receptors (0.95 potency relative to propranolol). It also demonstrates potent vasodilator activity (0.20 potency relative to propranolol; pA2 = 7.58).

Novel oxylipins, referred to as docosanoids, have been derived from C22polyunsaturated fatty acids 7(S),17(S)-dihydroxy-8(E),10(Z),13(Z),15(E),19(Z)-Docosapentaenoic acid (7(S),17(S)-hydroxy DPA) is a DPA-derived analog of the 17(S)-dihydroxy series of docosanoids known as protectins. Protectin D1, a DHA-derived dihydroxy fatty acid, exhibits potent anti-inflammatory activities.1,2,3Potentially, 7(S),17(S)-hydroxy DPA demonstrates similar properties; however, its biological activity has yet to be determined. 1.Serhan, C.N., Gotlinger, K., Hong, S., et al.Anti-inflammatory actions of neuroprotectin D1/protectin D1 and its natural stereoisomers: Assignments of dihydroxy-containing docosatrienesJ. Immunol.176(3)1848-1859(2006) 2.Ariel, A., and Serhan, C.N.Resolvins and protectins in the termination program of acute inflammationTRENDS in Immunology28(4)176-183(2007) 3.Schwab, J.M., Chiang, N., Arita, M., et al.Resolvin E1 and protectin D1 activate inflammation-resolution programmesNature447(7146)869-874(2007)

Theophylline, 7-(2-(diethylamino)ethyl)-6-thio-, hydrochloride is a bioactive chemical.

A-7 hydrochloride 是一种钙调蛋白拮抗剂，会引起 MDA-MB-231细胞中 CD44+CD24-亚群的改变。

13-Acetoxy-3beta-hydroxygermacra-1(10)E,4E,7(11)-trien-12,6alpha-olide is a natural product from Artemisia myriantha.

7-Deoxy-10-hydroxyloganetin 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TN3223，CAS号为 76267-48-6。

7-Epi-10-deacetylcephalomannine is a natural product from Taxus sumatrana.

NH2-bicyclo[1.1.1]pentane-7-MAD-MDCPT（化合物I）盐酸盐是一种通过偶联抗体实现靶向细胞传递的拓扑异构酶I抑制剂，显示出优良的体内外ADC活性。

USP7-IN-10 hydrochloride (compound 1)是一种高效USP7抑制剂，具有13.39 nM的IC50值。

LH-RH (7-10)，一种由性腺激素释放激素 (LHRH) 在垂体和下丘脑降解过程中形成的主要四肽降解产物之一，存在于巨噬细胞、I 型样及II 型肺细胞中。

7-Epi-10-oxo-docetaxel (Docetaxel Impurity 2) is a docetaxel impurity identified by HPLC.

Docosapentaenoic acid (DPA) is a ω-3 fatty acid found in fish oils. 17-oxo-7(Z),10(Z),13(Z),15(E),19(Z)-docosapentaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DPA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

7-Acetoxy-15-methoxy-10-O-methyldihydrobotrydial 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T125441，CAS号为 196796-12-0。

W-7 hydrochloride (W-7 HCl) 是一种选择性的钙调蛋白拮抗剂。它抑制Ca2+-钙调蛋白依赖性磷酸二酯酶和肌球蛋白轻链激酶，IC50值分别为 28 μM 和 51 μM。它可诱导细胞凋亡，具有抗癌活性。

6-Methyl-1,3-dihydrofuro[3,4-c]pyridin-7-ol hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64405，CAS号为 1006-21-9。

17-oxo-4(Z),7(Z),10(Z),13(Z),15(E),19(Z)-Docosahexaenoic acid is a metabolite of lipoxygenase-mediated oxidation of DHA that is produced endogenously by aspirin-enhanced COX-2 activity. It has been shown to activate Nrf2-dependent antioxidant gene expression, to act as a PPARγ agonist (EC50 = ~200 nM), and to inhibit pro-inflammatory cytokine and nitric oxide production at biological concentration ranges (5-25 μM).

7-Aminomethyl-10-methyl-11-fluoro camptothecin为MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin的毒素分子，适用于喜树碱ADC的制备。

2-Amino-6-(propylamino)-5,6-dihydrobenzo[d]thiazol-7(4H)-one hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64682。

PSB-10 hydrochloride is a human adenosine A3 receptor antagonist.

10-DEBC hydrochloride 是选择性的Akt 抑制剂，IC50为 1.28 μM。10-DEBC hydrochloride 也是一种新型抗肺结核的化合物。

7-Epi 10-desacetyl paclitaxel (10-Deacetyl-7-epipaclitaxel) 是紫杉醇衍生物，对 HeLa 细胞具有细胞毒性(IC50:85 μM)。

7-Xylosyl-10-deacetylbaccatin III is a natural product from Taxus brevifolia.

Theophylline, 7-(2-oxo-4-piperidinobutyl)-6-thio-, hydrochloride is a bioactive chemical.

4(Z),7(Z),10(Z),13(Z),16(Z)-Nonadecapentaenoic acid is an unusual polyunsaturated fatty acid (PUFA) generated during the synthesis of docosahexaenoic acid-d5 . While the physiological properties of this compound are not known, dietary intake of n-3 long-chain PUFAs provides potential health benefits.

7-Xylosyl-10-deacetyltaxol C is a natural product from Taxus wallichiana Zucc.

(6R,7R)-4-Methoxybenzyl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65519，CAS号为 113479-65-5。

7-Xylosyl-10-deacetyltaxol B (7-xylosyl-10-Deacetylpaclitaxel B) 是一种来自红豆杉科植物东北红豆杉的紫杉醇衍生物，具有抗肿瘤活性，可用于合成紫杉醇。

10-Deacetyl-7-xylosyl paclitaxel (7-Xylosyl-10-deacetyltaxol) 是一种紫杉醇衍生物，具有改进的药理特性和更高的水溶性，用于治疗癌症。

HCV-IN-7 hydrochloride is an orally active and potent pan-genotypic HCV NS5A inhibitor (IC50s: 3-47 pM). It shows a superior pan-genotypic profile and a good pharmacokinetic profile coupled with a favorable liver uptake.

MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin (compound 21a), is a camptothecin payload which can be utilized in the synthesis of a camptothecin antibody-drug conjugate (ADC) by conjugation to a monoclonal antibody (mAb).

Acridan-9-carboxylic acid, 10-methyl-, 2-(diethylamino)ethyl ester, hydrochloride is a biochemical.

7-Aminomethyl-10-methyl-11-fluoro camptothecin TFA 为MC-AAA-NHCH2OCH2COO-7-aminomethyl-10-methyl-11-fluoro camptothecin的毒素分子，主要在合成喜树碱抗体偶联药物（ADC）中使用。