Mal-PEG4-PFPester is a non-cleavable antibody-drug conjugate (ADC) linker that incorporates a Maleimide moiety, a 4-unit Polyethylene Glycol (PEG) backbone, and a Pentafluorophenyl (PFP) ester.
Mal-amido-PEG3-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N-(Azido-PEG4)-N-Boc-PEG4-NHS ester is a PEG-based PROTAC linker featuring a terminal azide group. It is commonly employed in the synthesis of PROTACs[1].
Ald-Ph-amido-PEG3-C2-Pfpester is a noncleavable antibody-drug conjugate (ADC) linker that falls under the category of polyethylene glycol (PEG) linkers.
Boc-PEG4-phosphonic acid ethyl ester is a polyethylene glycol (PEG) derived linker compound employed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
PC Mal-NHS carbonate ester is a cleavable linker specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1]. This chemical compound plays a crucial role in facilitating the conjugation of drugs to antibodies, enabling targeted delivery and enhanced efficacy of therapeutic agents. Its unique carbonate ester structure allows for efficient cleavage in the targeted environment, ensuring the controlled release of the drug payload. Its application in ADC synthesis highlights its importance in the development of innovative and targeted cancer therapies.
Mal-PEG-mal (MW 2000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Diketone-PEG4-PFPester is a polyethylene glycol (PEG) derivative employed as a PROTAC linker in the fabrication of proteolysis-targeting chimeras (PROTACs)[1].
Azido-PEG8-PFPester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Mal-Amido-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Mal-PEG6-NHS ester is a noncleavable ADC linker consisting of a Maleimide functional group, a 6-unit Polyethylene Glycol (PEG) spacer, and an N-Hydroxysuccinimide (NHS) ester moiety.
Mal-PEG4-Boc is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N-Desthiobiotin-N-bis(PEG4-t-butyl ester) is a PEG-based linker compound employed for the synthesis of PROTACs, which are bifunctional molecules designed for targeted protein degradation[1].
Bis-PEG13-PFPester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
HO-PEG-mal (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
m-PEG4-O-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
N-(m-PEG4)-N'-(4-Hydroxycyclohexyl-1-amido-PEG4)-Cy5 is a polyethylene glycol (PEG)-based linker compound primarily utilized in the synthesis of proteolysis-targeting chimeras (PROTACs)[1].
endo-BCN-PEG4-NHS ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
m-PEG-mal (MW 30000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Mal-PEG4-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Mal-PEG-mal (MW 5000) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Bis-PEG1-PFPester is a non-cleavable ADC linker incorporating a 1-unit PEG moiety, specifically designed for the synthesis of antibody-drug conjugates (ADCs)[1].
DBCO-PEG4-PFPester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Biotin-PEG4-TFP ester is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
m-PEG4-CH2-methyl ester is a polyethylene glycol (PEG)- and Alkyl ester-based linker utilized in the fabrication of proteolysis targeting chimeras (PROTACs) [1].
Methyltetrazine-PEG4-SS-NHS ester is a cleavable, four-unit polyethylene glycol (PEG) linker commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].