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Search Results for " hypomethylation "
Targets Recommended: DNA Methyltransferase

1

抑制剂 & 化合物

1

重组蛋白

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Cat. No. Product Name Target Signaling Pathways
T11469 GSK-3484862

DNA Methyltransferase Chromatin/Epigenetic
GSK-3484862 是 有效的 DNA 甲基转移酶 Dnmt1的非共价抑制剂。GSK-3484862 通过诱导 DNA 低甲基化起抗癌作用。GSK-3484862 介导小鼠胚胎干细胞的整体去甲基化。

化合物

GSK-3484862
Cat.No: T11469
Synonym:
Target: DNA Methyltransferase
Cat. No. Product Name Species Expression System
TMPK-00710 Claudin-4 Protein-VLP, Human, Recombinant

Claudin4,CLDN4,Claudin-4,CPETR1,CPE-R,WBSCR8,CPE R

Human HEK293 Cells
Claudin-4 (CLDN4) is a key component of tight junctions (TJs) in epithelial cells. CLDN4 is overexpressed in many epithelial malignancies and correlates with cancer progression. Changes in CLDN4 expression have been associated with epigenetic factors (such as hypomethylation of promoter DNA), inflammation associated with infection and cytokines, and growth factor signaling. CLDN4 helps to maintain the tumor microenvironment by forming TJs and acts as a barrier to the entry of anticancer drugs in...

重组蛋白

Claudin-4 Protein-VLP, Human, Recombinant
Cat.No: TMPK-00710
Species: Human
Expression System: HEK293 Cells
TargetMol Loading
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