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TMPY-02929
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ENTPD2 Protein, Human, Recombinant (aa 29-460, His)
ectonucleoside triphosphate diphosphohydrolase 2,NTPDase-2,R...
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Human
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Baculovirus Insect Cells
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NTPDase 2, also known as ENTPD2, belongs to the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). Members of E-NTPDase family are nucleotidases able to hydrolyze 5′-nucleoside tri- and/or diphosphates; the main role of these enzymes is the termination of purinergic signaling. NTPDases are ubiquitous and were previously shown in other parasites including the trypanosomatides of genus Leishmania and in T. brucei. NTPase activity would act as a timer and is crucial to T. gondii in... |
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TMPH-00168
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Levanase Protein, Bacillus subtilis, Recombinant (His)
sacC,Exo-beta-D-fructosidase,Beta-D-fructofuranosidase,Levan...
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Bacillus subtilis
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E. coli
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Exo-fructosidase that can hydrolyze both levan and inulin, leading to the production of free fructose. Is also able to hydrolyze sucrose and to a small extent raffinose, but not melezitose, stachylose, cellobiose, maltose, and lactose. Levanase Protein, Bacillus subtilis, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 77.2 kDa and the accession number is P05656. |
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TMPH-02371
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SHV-5 Protein, Klebsiella pneumoniae, Recombinant (His & Myc)
Beta-lactamase SHV-5,bla
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Klebsiella pneumoniae
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E. coli
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SHV enzymes hydrolyze broad spectrum cephalosporins notably cefotaxime and ceftazidime. SHV-5 causes particularly high levels of resistance to aztreonam and ceftazidime. |
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TMPH-02340
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6GAL Protein, Hypocrea rufa, Recombinant (His)
Endo-beta-1,6-galactanase,6GAL
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Hypocrea rufa
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P. pastoris (Yeast)
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Hydrolyzes galactooligomers with a degree of polymerization higher than 3. Hydrolyzes radish root arabinogalactan-protein. Does not hydrolyze dextran, arabinan, starch, laminarin, beta-1,4- and beta-1,3-galactans, larch wood arabinogalactan or acid-insoluble polygalacturonic acid. |
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TMPH-02339
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6GAL Protein, Hypocrea rufa, Recombinant (E. coli, His)
Endo-beta-1,6-galactanase,6GAL
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Hypocrea rufa
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E. coli
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Hydrolyzes galactooligomers with a degree of polymerization higher than 3. Hydrolyzes radish root arabinogalactan-protein. Does not hydrolyze dextran, arabinan, starch, laminarin, beta-1,4- and beta-1,3-galactans, larch wood arabinogalactan or acid-insoluble polygalacturonic acid. |
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TMPH-01861
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LHPP Protein, Human, Recombinant (His & SUMO)
Phospholysine phosphohistidine inorganic pyrophosphate phosp...
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Human
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E. coli
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Phosphatase that hydrolyzes imidodiphosphate, 3-phosphohistidine and 6-phospholysine. Has broad substrate specificity and can also hydrolyze inorganic diphosphate, but with lower efficiency. LHPP Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 45.2 kDa and the accession number is Q9H008. |
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TMPH-03320
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IAP-1 Protein, Rat, Recombinant (His)
Intestinal alkaline phosphatase I,Intestinal-type alkaline p...
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Rat
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HEK293 Cells
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Alkaline phosphatase that can hydrolyze various phosphate compounds. IAP-1 Protein, Rat, Recombinant (His) is expressed in HEK293 mammalian cells with N-10xHis tag. The predicted molecular weight is 55.9 kDa and the accession number is P15693. |
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TMPH-01254
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DNM1 Protein, Human, Recombinant (His)
DNM,Dynamin,Dynamin-1,DNM1,Dynamin I
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Human
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E. coli
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Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis. DNM1 Protein, Human, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 32.2 kDa and the accession number is Q05193. |
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TMPH-03283
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CD39 Protein, Rat, Recombinant (His)
ATP diphosphohydrolase,Entpd1,Nucleoside triphosphate diphos...
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Rat
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Baculovirus Insect Cells
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In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. |
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TMPH-03284
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CD39 Protein, Rat, Recombinant (E. coli, His)
Entpd1,ATP-DPH,Ecto-ATP diphosphohydrolase 1,CD39,Ecto-ATPas...
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Rat
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E. coli
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In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Could also be implicated in the prevention of platelet aggregation by hydrolyzing platelet-activating ADP to AMP. Hydrolyzes ATP and ADP equally well. |
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TMPH-03181
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LaaA Protein, Pseudomonas azotoformans, Recombinant (His & Myc & SUMO)
L-amino acid amidase,laaA
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Pseudomonas azotoformans
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E. coli
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Hydrolyzes L-prolinamide, L-proline-p-nitroanilide, L-alaninamide, L-methioninamide, piperidine-2-carboxamide and piperazine-2-carboxamide. Has a much lower activity towards piperazine-2-tert-butylcarboxamide. Does not hydrolyze dipeptides and D-prolinamide. LaaA Protein, Pseudomonas azotoformans, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 54.5 kDa and the accession number is Q76KX0. |
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TMPJ-01117
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INPP5A Protein, Human, Recombinant (His)
INPP5A,Type I inositol 1,5-trisphosphate 5-phosphatase,Type ...
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Human
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HEK293 Cells
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Type I inositol 1,4,5-trisphosphate 5-phosphatase is a 412 amino acids protein that belongs to the inositol 1,4,5-trisphosphate 5-phosphatase type I family. Type I inositol-1,4,5-trisphosphate 5-phosphatase is an enzyme that in humans is encoded by the INPP5A gene. It is expressed in brain and high level in Purkinje cells. InsP3 5-phosphatases hydrolyze Ins(1,4,5)P3, which mobilizes intracellular calcium and acts as a second messenger mediating cell responses to various stimulation. |
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TMPY-03182
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PLRP2 Protein, Human, Recombinant (His)
PLRP2,pancreatic lipase-related protein 2
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Human
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Baculovirus Insect Cells
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Galactolipase, also known as PNLIPRP2, is a lipase with broad substrate specificity. It can hydrolyze both phospholipids and galactolipids. Galactolipase acts preferentially on monoglycerides, phospholipids and galactolipids. It also hydrolyses milk fat with a lower catalytic efficiency. The expressed galactolipase shows a lipolytic activity that is, however, only marginally dependent on the presence of colipase. The lipolytic activity of pancreatic extracts and human pancreatic juice on Labraso... |
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TMPH-00586
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Beta-lactamase TEM Protein, E. coli, Recombinant (His)
IRT-4,Penicillinase,TEM-2,TEM-16/CAZ-7,Beta-lactamase TEM,TE...
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E. coli
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P. pastoris (Yeast)
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TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lacta... |
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TMPJ-01241
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DTD1 Protein, Human, Recombinant (His)
DUE-B,D-tyrosyl-tRNA(Tyr) deacylase 1,DNA-unwinding element-...
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Human
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HEK293 Cells
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D-tyrosyl-tRNA(Tyr) deacylase 1(DTD1) belongs to the DTD family, and expressed in many adult and fetal tissues such as testis, ovary, spleen in adult and fetal brain. It is a nucleus and cytoplasm located protein, and is preferentially phosphorylated in cells arrested early in S phase. DTD1 is an ATPase involved in DNA replication, it may facilitate loading of CDC45 onto pre-replication complexes. The protein may hydrolyze D-tyrosyl-tRNA(Tyr) into D-tyrosine and free tRNA(Tyr), a possible defens... |
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TMPY-01579
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GBA3 Protein, Human, Recombinant (His)
glucosidase, beta, acid 3 (gene/pseudogene),GBA3,MGC126878,K...
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Human
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Baculovirus Insect Cells
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Cytosolic beta-glucosidase, also known as Cytosolic beta-glucosidase-like protein 1, GBA3, CBG and CBGL1 is a cytoplasm protein which belongs to theglycosyl hydrolase 1 family and Klotho subfamily. GBA3 / CBGL1 is a glycosidase probably involved in the intestinal absorption and metabolism of dietary flavonoid glycosides. GBA3 / CBGL1 is present in small intestine (at protein level). GBA3 / CBGL1 is expressed in liver, small intestine, colon, spleen and kidney. GBA3 / CBGL1 is down-regulated in r... |
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TMPY-03055
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LYG1 Protein, Human, Recombinant (His)
SALW1939,lysozyme G-like 1
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Human
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Baculovirus Insect Cells
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LYG1 (Lysozyme G1) is a Protein Coding gene. It belongs to the glycosyl hydrolase 23 family. Glycoside hydrolases are a widespread group of enzymes that hydrolyze the glycosidic bond between two or more carbohydrates, or between a carbohydrate and a non-carbohydrate moiety. LYG1 exhibits hydrolase activity, acting on glycosyl bonds (inferred); lysozyme activity (inferred). It is found in the extracellular region and may function in the cell wall macromolecule catabolic process, metabolic process... |
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TMPH-00587
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Beta-lactamase TEM Protein, E. coli, Recombinant (His & SUMO)
IRT-4,TEM-16/CAZ-7,Penicillinase,Beta-lactamase TEM,TEM-2,TE...
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E. coli
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E. coli
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TEM-type are the most prevalent beta-lactamases in enterobacteria; they hydrolyze the beta-lactam bond in susceptible beta-lactam antibiotics, thus conferring resistance to penicillins and cephalosporins. TEM-3 and TEM-4 are capable of hydrolyzing cefotaxime and ceftazidime. TEM-5 is capable of hydrolyzing ceftazidime. TEM-6 is capable of hydrolyzing ceftazidime and aztreonam. TEM-8/CAZ-2, TEM-16/CAZ-7 and TEM-24/CAZ-6 are markedly active against ceftazidime. IRT-4 shows resistance to beta-lacta... |
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TMPY-03508
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XTP3TPA Protein, Human, Recombinant (His)
XTP3TPA,dCTP pyrophosphatase 1,RS21C6,CDA03
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Human
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E. coli
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DCTPP1 hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. It has a strong preference for modified dCTP. DCTPP1’s activity is highest with 5-iodo-dCTP, followed by 5-bromo-dCTP, unmodified dCTP, 5-methyl-dCTP and 5-chloro-dCTP. DCTPP1 also hydrolyzes 2-chloro-dATP and 2-hydroxy-dATP with lower efficiency, and has even lower activity with unmodified dATP, dTTP and dUTP (in vitro). DCTPP1 does not hydrolyze ATP, UTP, ITP, GTP, dADP, dCDP or dGTP.... |
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TMPY-04100
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MMP-26 Protein, Human, Recombinant
matrix metallopeptidase 26,MMP26
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Human
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E. coli
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MMP26 (Matrix Metallopeptidase 26) is a Protein Coding gene. MMP26 is a member of matrix metalloproteinases (MMPs) and has been reported to be highly expressed in many cancers. The protein differs from most MMP family members in that it lacks a conserved C-terminal protein domain. It may hydrolyze collagen type IV, fibronectin, fibrinogen, beta-casein, type I gelatin, and alpha-1 proteinase inhibitor, and is also able to activate progelatinase B. MMP26 is a target gene of miR-125b, and the expre... |
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TMPY-03849
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NUDT5 Protein, Human, Recombinant (His)
hYSAH1,YSAH1,nudix (nucleoside diphosphate linked moiety X)-...
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Human
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E. coli
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NUDT5 (Nudix Hydrolase 5) is a Protein Coding gene. This gene belongs to the Nudix (nucleoside diphosphate linked moiety X) hydrolase superfamily. The encoded enzyme catalyzes the hydrolysis of modified nucleoside diphosphates. ADP-sugar Pyrophosphatase, also known as NUDT5, eliminates toxic nucleotide derivatives from the cell and regulates the levels of important signaling nucleotides and their metabolites. It is widely expressed in the liver, skin, and other tissues. NUDT5 functions as a MutT... |
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TMPJ-00386
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ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Metalloprotease MPROT15,ACEH,Angiotensin-Converting Enzyme H...
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Human
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HEK293 Cells
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Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate... |
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TMPH-01624
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GBA Protein, Human, Recombinant
Lysosomal glycosylceramidase,Acid beta-glucosidase,Alglucera...
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Human
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E. coli
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Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... |
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TMPY-01140
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ACOT13/THEM2 Protein, Human, Recombinant (His)
THEM2,HT012,ACOT13,PNAS-27,acyl-CoA thioesterase 13
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Human
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E. coli
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The metabolites of fatty acyl-Coenzyme A (CoA) and metabolic enzymes contribute to lipid biosynthesis, signal transduction, and gene transcription. Members of the acyl-CoA thioesterase (Acot) gene family hydrolyze fatty acyl-CoAs, but their biological functions remain incompletely understood. Thioesterase superfamily member 2 (Them2; synonym Acot13) is enriched in oxidative tissues, associated with mitochondria, and relatively specific for long chain fatty acyl-CoA substrates. Using Them2(-/-) m... |
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TMPH-01623
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GBA Protein, Human, Recombinant (His & Myc & SUMO)
Lysosomal acid glucosylceramidase,GBA1,Lysosomal galactosylc...
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Human
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E. coli
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Glucosylceramidase that catalyzes, within the lysosomal compartment, the hydrolysis of glucosylceramide/GlcCer into free ceramide and glucose. Thereby, plays a central role in the degradation of complex lipids and the turnover of cellular membranes. Through the production of ceramides, participates in the PKC-activated salvage pathway of ceramide formation. Also plays a role in cholesterol metabolism. May either catalyze the glucosylation of cholesterol, through a transglucosylation reaction tha... |
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TMPY-02880
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ENPP5 Protein, Human, Recombinant (His)
NPP-5,ectonucleotide pyrophosphatase/phosphodiesterase 5 (pu...
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Human
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HEK293 Cells
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ENPP5 is a member of the nucleotide pyrophosphatase/phosphodiesterase family (NPP). It is a family comprised of dimeric enzymes that catalyze the hydrolysis of phosphate diester bonds. There are seven isoforms in NPP family, some of which prefer nucleotide substrates, some of which prefer phospholipid substrates, and others of which prefer substrates that have not yet been determined. NPP also belongs to the alkaline phosphatase (AP) superfamily of enzymes and they are located in the cell membra... |
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TMPY-02132
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LYPLA2 Protein, Human, Recombinant (His)
APT-2,lysophospholipase II,DJ886K2.4,APT2
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Human
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E. coli
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Lysophospholipase II (LYPLA2, LPL-II, or LysoPLA II), also known as Acyl-protein thioesterase 2 (APT-2), belongs to the AB hydrolase 2 family. This enzyme has lysophospholipase activity and may hydrolyze fatty acids from S-acylated cysteine residues in proteins such as trimeric G alpha proteins or HRAS. Acyl-protein thioesterase 1 (APT-1) and Acyl-protein thioesterase 2 (APT-2) are cytosolic lysophospholipids hydrolyzing enzymes. The serum activity of APT-1 may play an important role in the dete... |
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TMPY-02129
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Transglutaminase 3/TGM3 Protein, Human, Recombinant (His)
transglutaminase 3,UHS2,TGE
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Human
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Baculovirus Insect Cells
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Transglutaminases (TGase) are a family of calcium-dependent acyl-transfer enzymes ubiquitously expressed in mammalian cells and responsible for catalyzing covalent cross-links between proteins or peptides. Transglutaminase 3 (TGM3) is a member of a family of Ca2+-dependent enzymes that catalyze covalent cross-linking reactions between proteins or peptides. TGM3 isoform is widely expressed and is important for epithelial barrier formation. It is a zymogen, requiring proteolysis for activity. Calc... |
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TMPJ-01450
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SARS-CoV-2 Helicase Protein (His & MBP)
SARS-CoV 2 nsp13,SARS-CoV 2 Helicase
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SARS-CoV-2
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E. coli
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The non—structural protein 13 (nsp13) of SARS—CoV 2 is a helicase that separates double—stranded RNA or DNA with a 5'—3' polarity, using the energy of nucleotide hydrolysis. A basic biochemical characterization of nsp13 demonstrated that it can unwind both doublestranded DNA and RNA in a 5’-3’ direction, and it can hydrolyze all deoxyribonucleotide and ribonucleotide triphosphates. Helicases are motor proteins that utilize the energy derived from nucleotide hydrolysisto unwind double-stranded nu... |
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TMPH-02549
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FHIT Protein, Mouse, Recombinant (His)
Adenylylsulfatase,Adenylylsulfate-ammonia adenylyltransferas...
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Mouse
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E. coli
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Possesses dinucleoside triphosphate hydrolase activity. Cleaves P(1)-P(3)-bis(5'-adenosyl) triphosphate (Ap3A) to yield AMP and ADP. Can also hydrolyze P(1)-P(4)-bis(5'-adenosyl) tetraphosphate (Ap4A), but has extremely low activity with ATP. Exhibits adenylylsulfatase activity, hydrolyzing adenosine 5'-phosphosulfate to yield AMP and sulfate. Exhibits adenosine 5'-monophosphoramidase activity, hydrolyzing purine nucleotide phosphoramidates with a single phosphate group such as adenosine 5'monop... |
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TMPH-02133
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DDX39B Protein, Human, Recombinant (GST)
UAP56,HLA-B-associated transcript 1 protein,DDX39B,ATP-depen...
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Human
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E. coli
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Involved in nuclear export of spliced and unspliced mRNA. Assembling component of the TREX complex which is thought to couple mRNA transcription, processing and nuclear export, and specifically associates with spliced mRNA and not with unspliced pre-mRNA. TREX is recruited to spliced mRNAs by a transcription-independent mechanism, binds to mRNA upstream of the exon-junction complex (EJC) and is recruited in a splicing- and cap-dependent manner to a region near the 5' end of the mRNA where it fun... |
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