HO-PEG-CH2COOH (MW3400) is a PEGylated PROTAC linker with a molecular weight of 3400. It serves as a PEG-based building block for the synthesis of PROTACs[1].
Pomalidomide-C2-amido-(C1-O-C5-O-C1)2-COOH is a chemically synthesized compound, designed as an E3 ligase ligand-linker conjugate, integrating the cereblon ligand derived from Pomalidomide and a linker employed in PROTAC technology. This compound serves to facilitate targeted protein degradation through the modulation of E3 ligase activity, enabling the selective elimination of specific proteins of interest.
Mal-PEG-mal (MW3400) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
HO-PEG-mal (MW3400) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
Amine-PEG-thiol (MW3400) is a polyethylene glycol (PEG)-based linker molecule containing an amine group and a thiol group. It serves as an essential component in the synthesis of proteolysis targeting chimeras (PROTACs)[1].
HO-PEG-amine (MW3400) is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
DSPE-PEG-2-Aminoethyl-alpha-mannopyranoside (MW 2000) is a polyethylene glycol (PEG) derived linker. This specific linker is utilized in the synthesis of PROTACs, or proteolysis targeting chimeras [1].