h 8 (hydrochloride)

H-8 hydrochloride 是一种具有可逆性和 ATP 竞争性的 PKA 抑制剂。可用研究代谢疾病。

LYS006 hydrochloride (1799681-85-8 Free base) 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T9690L。

SB1317 hydrochloride (1204918-72-8(free base)) (TG-02 hydrochloride) 是一种有效的 CDK2 JAK2 FLT3 抑制剂（IC50：13 73 56 nM）。

H-Arg(Pbf)-OMe hydrochloride 是一种精氨酸类似物。

H-Ile-Pro-Pro-OH hydrochloride，一种源自乳制品的三肽，通过抑制血管紧张素转换酶 (ACE)，IC50为5 μM，展现出抗高血压效果。

PSN 375963 hydrochloride 是一种有效的GPR119激动剂，对人和小鼠GPR119的EC50分别为 8.4 和 7.9 μM。PSN 375963 hydrochloride 表现出与内源性油酰乙醇酰胺 (OEA) 相似的效力。

TLR7 8 agonist 4 hydroxy-PEG10-acid hydrochloride (compound 9) is a drug-linker conjugate used in antibody-drug conjugates (ADCs) with high efficacy against tumors. It consists of TLR7 8 agonist 4, a potent TLR7 8 agonist, linked to the ADC linker hydroxy-PEG10-acid which can be cleaved.

TLR7 8 agonist 4hydroxy-PEG6-acid hydrochloride为一种用于抗体药物偶联体(ADC)的药物-连接子偶联物。该化合物为TLR7 8 agonist 4hydroxy-PEG6-acid的盐酸盐形式，由TLR7 8 agonist 4与连接子 Hydroxy-PEG6-acid构成，适用于ADC合成。

PROTAC(H-PGDS)-8，一种针对造血前列腺素D合酶 (H-PGDS) 的PROTAC降解剂，具有 0.14 μM 的IC50值。

CBB1007 Hcl is a selective, reversible, and substrate competitive LSD1 inhibitor (IC50: 5.27 μM for hLSD1).

TMB 8 is a non-competitive antagonist of nicotinic acetylcholine receptors (nAChRs) with IC50 values of 390 and 350 nM, respectively, for human muscle-type and α3β4 subunit-containing ganglionic nAChRs expressed in TE671 RD or SH-SY5Y cells. It inhibits nicotine-induced dopamine release from rat brain synaptosomes (IC50 = 480 nM). TMB 8 also reduces calcium availability in smooth and skeletal muscle, blocking the contractile response in isolated rabbit aortic strip when used at a concentration of 50 μM and inhibiting calcium influx and efflux in isolated guinea pig ileum when used at a concentration of 65 μM. It has been used in the study of intracellular calcium dynamics, particularly in smooth muscle. TMB 8 also inhibits protein kinase C (PKC) activity in a dose-dependent manner.

H-(Gly)3-Lys(N3)-OH(hydrochloride) 是一种点击化学试剂，在核酸、脂类、蛋白质及其他分子的结合应用中展现出巨大潜力，其高产率、高特异性和操作简便的特点使其在众多研究领域得到应用。

8-Hydroxyguanine, generated through the oxidative degradation of DNA by the hydroxyl radical, serves as an indicator of oxidative stress in biological systems.

(6R,7R)-4-Methoxybenzyl 7-amino-3-(chloromethyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylate hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T65519，CAS号为 113479-65-5。

Two Rho-associated kinases (ROCK), ROCK-I and ROCK-II, act downstream of the G protein Rho to regulate cytoskeletal stability. The ROCKs play important roles in diverse cellular functions including cell adhesion and proliferation, smooth muscle contraction, and stem cell renewal. Glycyl-H-1152 is a selective and potent ROCK inhibitor (IC50 = 11.8 nM for ROCK-II). It is a glycylated isoquinoline compound derived from the therapeutically-important ROCK inhibitor HA-1077 (Fasudil) and exhibits better specificity. Thus, it poorly inhibits Ca2+/calmodulin-dependent kinase type II, protein kinase (PK) G, and Aurora A (IC50 = 2.57, 2.35, and 3.26 μM, respectively) as well as PKA or PKC (IC50 ≥ 10 μM for each). The potency of Glycyl-H-1152 is superior to that of other ROCK inhibitors, including Y-27632 (Ki = 220 nM) and HA-1077 (IC50 = 158 nM).

H-D-Phe-Pip-Arg-pNA hydrochloride, a chromogenic substrate, mimics the N-terminal segment of the A alpha chain of fibrinogen, the native substrate of thrombin. It displays specificity towards thrombin and is employed for quantifying antithrombin-heparin cofactor (AT-III). The utilization of H-D-Phe-Pip-Arg-pNA hydrochloride in the AT-III assay enables a sensitive, accurate, and straightforward measurement process.

N-(5-(8-Amino-3-methyl-[1,2,4]triazolo[4,3-b]pyridazin-6-yl)-2-methylphenyl)methanesulfonamide hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T64837。

(1'R,3a'R,8a'S,9'S,9a'S)-1'-Methyl-3'-oxo-N,N-diphenyl-3',3a',5',7',8',8a',9',9a'-octahydro-1'H-spiro[[1,3]dioxolane-2,6'-naphtho[2,3-c]furan]-9'-carboxamide 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T67324，CAS号为 900160-98-7。

GNE-617 hydrochloride is a potent and competitive inhibitor of nicotinamide phosphoribosyltransferase (IC50: 5nM). GNE-617 hydrochloride reduces the NAD levels in a > 95% reduction in both NAPRT1-deficient and NAPRT1-proficient cell lines and exerts (EC50

H-Hyp-OMe hydrochloride 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T66595，CAS号为 40216-83-9。

Taltobulin hydrochloride is a synthetic analogue of the tripeptide hemiasterlin, is a potent agent of antimicrotubule that circumvents P-glycoprotein-mediated resistance in vitro and in vivo.

Ro 8-4304 hydrochloride is a NMDA receptor antagonist.

H-L-Lys(Norbornene-methoxycarbonyl)-OH hydrochloride 是一种衍生自降冰片烯的赖氨酸，具备点击功能化的潜力。该化合物适用于无铜催化的点击反应，能对蛋白质进行温和而选择性的修饰。

H-D-Aha-OH (hydrochloride) 是点击化学中用于叠氮基偶联的试剂。

H-L-Lys(4-N3-Z)-OH hydrochloride 是一种赖氨酸修饰的点击化学试剂，其特征在于含有叠氮基团。该化合物不仅可用作生物正交连接的工具，而且还被应用于红外探针和光亲和试剂领域。