way 100635

WAY-100635 is a potent and selective 5-hydroxytryptamine 1A (5-HT1A) receptor antagonist with an IC50 of 0.91 nM and Ki of 0.39 nM. It exhibits pIC50 values of 8.9 and 6.6 for 5-HT1A and α1-adrenergic receptors, respectively. Moreover, WAY-100635 acts as a potent agonist of the dopamine D4 receptor [1] [2] [3].

WAY-100635 maleate 是一种选择性的5-hydroxytryptamine 1A 受体拮抗剂，IC50值为 0.91 nM，Ki 值为 0.39 nM。它也是多巴胺 D4受体激动剂，对于5-HT1A 和 α1-肾上腺素的 pIC50值分别为 8.9 和 6.6。

WAY-100635 Maleate is a specific and effective 5-HT receptor antagonist (IC50=0.95 nM).