Powder: -20°C for 3 years | In solvent: -80°C for 1 year
Bithionol (Actamer) 是一种抗寄生虫药物,对若干癌细胞有抑制作用。
产品描述 | Bithionol (Actamer), formerly marketed as an active ingredient in various topical drug products, was shown to be a potent photosensitizer with the potential to cause serious skin disorders. Approvals of the NDA's for bithionol drug products were withdrawn on October 24, 1967. |
靶点活性 | sAC:4.0 μM |
细胞实验 | Ovarian cancer cell lines (5 × 103 cells/well) were plated into 96-well flat bottom plates (Corning, Inc., Corning, NY) and incubated for overnight. Cells were treated with different concentrations of BT ranging from 0.178 μM to 400 μM and further incubated for 48 hrs or 72 hrs. (Only for Reference) |
别名 | 硫双二氯酚, Actamer, 硫氯酚 |
分子量 | 356.05 |
分子式 | C12H6Cl4O2S |
CAS No. | 97-18-7 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 60 mg/mL (168.52 mM)
H2O: < 1 mg/mL (insoluble or slightly soluble)
Ethanol: 21 mg/mL (59 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO / Ethanol | 1 mM | 2.8086 mL | 14.043 mL | 28.0859 mL | 70.2149 mL |
5 mM | 0.5617 mL | 2.8086 mL | 5.6172 mL | 14.043 mL | |
10 mM | 0.2809 mL | 1.4043 mL | 2.8086 mL | 7.0215 mL | |
20 mM | 0.1404 mL | 0.7021 mL | 1.4043 mL | 3.5107 mL | |
50 mM | 0.0562 mL | 0.2809 mL | 0.5617 mL | 1.4043 mL | |
DMSO | 100 mM | 0.0281 mL | 0.1404 mL | 0.2809 mL | 0.7021 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
Bithionol 97-18-7 GPCR/G Protein Microbiology/Virology cAMP Parasite 硫双二氯酚 allosteric Actamer 4-4 cell 硫氯酚 Inhibitor adenylate cyclase Infection cestode inhibit Bacterial inhibitor