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Vicriviroc maleate (SCH-417690 (maleate)) 是一种可口服,可透过血脑屏障的 CCR5选择性拮抗剂,同时抑制外周血单核细胞中的 HIV-1 的活性。
Vicriviroc maleate (SCH-417690 (maleate)) 是一种可口服,可透过血脑屏障的 CCR5选择性拮抗剂,同时抑制外周血单核细胞中的 HIV-1 的活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 572 | 现货 | |
5 mg | ¥ 1,380 | 现货 | |
10 mg | ¥ 1,980 | 现货 | |
25 mg | ¥ 3,760 | 现货 | |
50 mg | ¥ 5,270 | 现货 | |
100 mg | ¥ 7,380 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 1,920 | 现货 |
产品描述 | Vicriviroc maleate (SCH-417690 (maleate))(Sch-417690) is a piperazine-based CCR5 receptor antagonist with activity against human immunodeficiency virus. The IC50 value is 0.91 nM in clinical development for the treatment of HIV-1. |
靶点活性 | CCR5 receptor:0.91 nM |
别名 | 维立韦罗马来酸盐, SCH-D (maleate), SCH-417690 (maleate) |
分子量 | 649.7 |
分子式 | C32H42F3N5O6 |
CAS No. | 599179-03-0 |
Smiles | OC(=O)\C=C/C(O)=O.COC[C@H](N1CCN(C[C@@H]1C)C1(C)CCN(CC1)C(=O)c1c(C)ncnc1C)c1ccc(cc1)C(F)(F)F |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 50 mg/mL (76.96 mM), Sonication is recommended. H2O: 25 mg/mL (38.48 mM), Sonication and heating are recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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