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Quinine 是一种从金鸡纳树皮中提取的生物碱,用于预防和治疗疟疾。它也用于特发性肌肉痉挛,可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其IC50值为 169 μM,是一种钾离子通道抑制剂。
Quinine 是一种从金鸡纳树皮中提取的生物碱,用于预防和治疗疟疾。它也用于特发性肌肉痉挛,可抑制电压脉冲引起的 MT mSlo3 (KCa5.1) 通道 +100 mV 电流, 其IC50值为 169 μM,是一种钾离子通道抑制剂。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 mg | ¥ 317 | 现货 | |
1 g | ¥ 413 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 413 | 现货 |
产品描述 | Quinine is a natural cinchona alkaloid that has been used for centuries in the prevention and therapy of malaria. Quinine is also used for idiopathic muscle cramps. Quinine therapy has been associated with rare instances of hypersensitivity reactions which can be accompanied by hepatitis and mild jaundice. |
靶点活性 | K+ channel:169 μM |
别名 | 奎宁, 奎宁树 |
分子量 | 324.42 |
分子式 | C20H24N2O2 |
CAS No. | 130-95-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 50 mg/mL (154.12 mM) H2O: Insoluble | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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