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WK88-1 作为Hsp90的抑制剂,能在抗吉非替尼的H1975细胞系中促使多个致癌信号分子如EGFR、ErbB2和ErbB3的降解,从而引发生长阻滞和细胞凋亡。
WK88-1 作为Hsp90的抑制剂,能在抗吉非替尼的H1975细胞系中促使多个致癌信号分子如EGFR、ErbB2和ErbB3的降解,从而引发生长阻滞和细胞凋亡。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
10 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 |
产品描述 | WK88-1, an inhibitor of Hsp90, effectively induces the degradation of various oncogenic signaling molecules, including EGFR, ErbB2, and ErbB3, in the gefitinib-resistant H1975 cell line. This leads to subsequent growth arrest and apoptosis. |
分子量 | 502.64 |
分子式 | C28H42N2O6 |
CAS No. | 958888-32-9 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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