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Acetohexamide (Acetohexamid) 是磺脲类试剂,可刺激胰腺分泌胰岛素,能够用于 2 型糖尿病的相关研究。
Acetohexamide (Acetohexamid) 是磺脲类试剂,可刺激胰腺分泌胰岛素,能够用于 2 型糖尿病的相关研究。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 mg | ¥ 197 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 277 | 现货 |
产品描述 | Acetohexamide (Acetohexamid) is an intermediate-acting, first-generation sulfonylurea with hypoglycemic activity. It inhibits sulfonylurea receptor 1 (SUR1) linked to the inwardly rectifying potassium channel (KIR6.2) with Ki values of 22.9 and 14.2 μM in HEK293 cells transfected with the human receptor and in rat brain, respectively. Acetohexamide is metabolized in the liver to its active metabolite hydroxyhexamide. |
靶点活性 | SUR1:22.9 µM(Ki), KIR6.2:14.2 µM(Ki) |
别名 | 醋磺己脲, 醋磺环已脲, Gamadiabet, Dymelor, Acetohexamid |
分子量 | 324.4 |
分子式 | C15H20N2O4S |
CAS No. | 968-81-0 |
Smiles | CC(=O)c1ccc(cc1)S(=O)(=O)NC(=O)NC1CCCCC1 |
密度 | 1.3g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 30 mg/mL (92.48 mM) | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
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