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CMPD1 是非 ATP 竞争性 p38 MAPK 介导的 MK2磷酸化选择性抑制剂(Ki:330 nM)。
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CMPD1 是非 ATP 竞争性 p38 MAPK 介导的 MK2磷酸化选择性抑制剂(Ki:330 nM)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 459 | 现货 | |
5 mg | ¥ 995 | 现货 | |
10 mg | ¥ 1,650 | 现货 | |
25 mg | ¥ 2,780 | 现货 | |
50 mg | ¥ 3,970 | 现货 | |
100 mg | ¥ 5,790 | 现货 | |
200 mg | ¥ 7,830 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 1,180 | 现货 |
产品描述 | CMPD1 is a non-ATP-competitive p38 MAPK-mediated MK2 phosphorylation inhibitor(apparent Ki (Kiapp): 330 nM). |
靶点活性 | MK2:(Kiapp)330 nM |
体外活性 | CMPD1 inhibits tubulin polymerisation in glioblastoma cells[3]. But, CMPD1 does not inhibit p38 MAPK-mediated phosphorylation of other two substrates, MBP and ATF2. CMPD1 induced mitotic arrest and apoptosis in U87 cells[1]. |
分子量 | 349.4 |
分子式 | C22H20FNO2 |
CAS No. | 41179-33-3 |
Smiles | Oc1ccc(NC(=O)CCCc2ccc(cc2)-c2ccccc2F)cc1 |
密度 | 1.229g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 55 mg/mL (157.41 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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