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PPARγ agonist16 (Compound 4G) 是一种PPARγ激动剂,能够竞争性结合PPARγ的LBD结构域,其IC50为1790 nM。此化合物在小鼠模型中抑制耳朵肿胀,并在Streptozotocin诱导的小鼠糖尿病模型中展现抗高血糖作用。
PPARγ agonist16 (Compound 4G) 是一种PPARγ激动剂,能够竞争性结合PPARγ的LBD结构域,其IC50为1790 nM。此化合物在小鼠模型中抑制耳朵肿胀,并在Streptozotocin诱导的小鼠糖尿病模型中展现抗高血糖作用。
产品描述 | PPARγ agonist16 (Compound 4G) is a PPARγ agonist that competitively binds to the ligand-binding domain (LBD) of PPARγ with an IC50 of 1790 nM. It reduces ear swelling in mouse models and exhibits antihyperglycemic activity in mice with Streptozotocin-induced diabetes. |
靶点活性 | PPARγ:1790 nM |
分子量 | 432.29 |
分子式 | C19H14BrNO4S |
CAS No. | 2218046-01-4 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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