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Trimebutine (Mebutin) 是阿片受体激动剂,有抗毒蕈碱活性。它是解痉剂,可调节肠道和结肠运动,并通过抗毒蕈碱和弱μ-阿片受体激动剂作用缓解腹痛。
Trimebutine (Mebutin) 是阿片受体激动剂,有抗毒蕈碱活性。它是解痉剂,可调节肠道和结肠运动,并通过抗毒蕈碱和弱μ-阿片受体激动剂作用缓解腹痛。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
200 mg | ¥ 108 | 现货 | |
500 mg | ¥ 173 | 现货 | |
1 g | ¥ 248 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 150 | 现货 |
产品描述 | Trimebutine (Mebutin) is a spasmolytic agent that regulates intestinal and colonic motility and relieves abdominal pain with antimuscarinic and weak mu-opioid agonist effects. It is marketed for the treatment of irritable bowel syndrome (IBS) and lower gastrointestinal tract motility disorders, with IBS being one of the most common multifactorial GI disorders. It is used to restore normal bowel function and is commonly present in pharmaceutical mixtures as trimebutine maleate salt form. Trimebutine is not an FDA-Approved/Clinical drug, but it is available in Canada and several other international countries. |
别名 | 曲美布汀, Mebutin |
分子量 | 387.47 |
分子式 | C22H29NO5 |
CAS No. | 39133-31-8 |
Smiles | C(COC(=O)C1=CC(OC)=C(OC)C(OC)=C1)(N(C)C)(CC)C2=CC=CC=C2 |
密度 | 1.10 g/cm3 (20°C) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | Ethanol: < 1 mg/mL (insoluble or slightly soluble) DMSO: 45 mg/mL (116.14 mM) H2O: < 1 mg/mL (insoluble or slightly soluble) | |||||||||||||||||||||||||||||||||||
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