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Vortioxetine (Lu AA 21004) 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂,Ki 值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药,用于治疗重度抑郁症。
Vortioxetine (Lu AA 21004) 是5-HT1A、5-HT1B、5-HT3A、5-HT7受体和 5-羟色胺转运体抑制剂,Ki 值分别为 15、33、3.7、19 和 1.6 nM。它作为抗抑郁药,用于治疗重度抑郁症。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 257 | 现货 | |
10 mg | ¥ 413 | 现货 | |
25 mg | ¥ 658 | 现货 | |
50 mg | ¥ 913 | 现货 | |
100 mg | ¥ 1,230 | 现货 | |
200 mg | ¥ 1,980 | 现货 | |
500 mg | ¥ 3,710 | 现货 | |
1 g | ¥ 5,330 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 337 | 现货 |
产品描述 | Vortioxetine (Lu AA 21004) is a serotonergic antidepressant used for major depression disorders. Vortioxetine has been associated with a low rate of minor serum aminotransferase elevations during treatment. |
靶点活性 | SERT:1.6 nM (Ki), 5-HT1A:15 nM (Ki), 5-HT1B:33 nM (Ki), 5-HT3A:3.7 nM (Ki), 5-HT7:19 nM (Ki) |
别名 | 沃替西汀, Lu AA 21004 |
分子量 | 298.45 |
分子式 | C18H22N2S |
CAS No. | 508233-74-7 |
Smiles | S(C1=C(C=CC=C1)N2CCNCC2)C3=C(C)C=C(C)C=C3 |
密度 | 1.16 g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||||||||||||
溶解度信息 | Ethanol: 200 mM DMSO: 5 mg/mL (16.75 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||||||||||||
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