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SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.
SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity. |
靶点活性 | STAT3:9 nM (ki) |
体外活性 | In MOLM-16 cells, SI-109 exerts a moderate growth inhibitory activity with IC50 of 3 μM. SI-109 is ineffective in inhibition of STAT3 Y705 phosphorylation and in suppression of c-Myc expression at concentrations as high as 10 μM. |
分子量 | 835.79 |
分子式 | C40H44F2N7O9P |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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