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Xylitol (Ribitol) 是一种五碳糖醇,通过还原羰基衍生自木糖。它和蔗糖一样甜,可用作防龋甜味剂。
Xylitol (Ribitol) 是一种五碳糖醇,通过还原羰基衍生自木糖。它和蔗糖一样甜,可用作防龋甜味剂。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
500 mg | ¥ 123 | 现货 | |
1 g | ¥ 163 | 现货 | |
5 g | ¥ 359 | 现货 | |
10 g | ¥ 518 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 179 | 现货 |
产品描述 | Xylitol (Ribitol) is a five-carbon sugar alcohol derived from XYLOSE by reduction of the carbonyl group. It is as sweet as sucrose and used as a noncariogenic sweetener. |
体外活性 | Xylitol 抑制LPS诱导的炎性细胞因子的表达[2]。Xylitol 强烈抑制HUVEC的管腔形成、迁移以及侵袭,并以剂量依赖的方式降低关键促血管生成分子及其受体(VEGF, KDR, bFGF及bFGFR-II)的mRNA表达。此外,Xylitol 还能抑制HUVEC的NF-κB和Akt活化[1]。 |
体内活性 | Xylitol 在狗体内触发胰岛素释放[3]并抑制体内血管生成。在Matrigel实验中,Xylitol 显著抑制新微血管的形成,并减少Matrigel栓中的血红蛋白含量[1]。 |
细胞实验 | In vitro tube formation assay:HUVECs (2×104 cells) are seeded on a layer of previously polymerized Matrigel and treated with or without xylitol. Matrigel culture is incubated at 37°C. After 6 h, changes in cell morphology are captured through a phase contrast microscope and photographed at ×40 magnification. Each sample is assayed in duplicate and independent experiments are repeated three times. (Only for Reference) |
别名 | 木糖醇, Xylite, Ribitol, D-Xylitol, Adonitol, Adonite |
分子量 | 152.15 |
分子式 | C5H12O5 |
CAS No. | 87-99-0 |
Smiles | C(C(CO)O)(C(CO)O)O |
密度 | 1.52. |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | H2O: 197.2 mM DMSO: 45 mg/mL (295.76 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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