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AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).
AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
25 mg | 询价 | 10-14周 | |
50 mg | 询价 | 10-14周 | |
100 mg | 询价 | 10-14周 |
产品描述 | AM-6494 is a potent and orally active BACE1 inhibitor (IC50: 0.4 nM) with in vivo selectivity over BACE2 (IC50: 18.6 nM). |
靶点活性 | BACE2:18.6 nM , BACE1: |
分子量 | 473.5 |
分子式 | C22H21F2N5O3S |
CAS No. | 1874232-80-0 |
密度 | 1.44 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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