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L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物,具有抗血栓形成的作用,通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵,抑制 FeCl 3诱导的动脉血栓形成,减轻了短暂性大脑中动脉闭塞(tMCAO)小鼠模型的脑内血栓形成和炎症。
L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride)是一种脂肪酸代谢产物,具有抗血栓形成的作用,通过抵消tMCAO模型中的脑内血栓形成来保护小鼠免受缺血性中风。L-Palmitoylcarnitine chloride抑制心脏中的Na/K泵,抑制 FeCl 3诱导的动脉血栓形成,减轻了短暂性大脑中动脉闭塞(tMCAO)小鼠模型的脑内血栓形成和炎症。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 369 | 现货 | |
5 mg | ¥ 828 | 现货 | |
10 mg | ¥ 1,270 | 现货 | |
25 mg | ¥ 2,150 | 现货 | |
50 mg | ¥ 3,180 | 现货 | |
100 mg | ¥ 4,680 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 892 | 现货 |
产品描述 | L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties that protects mice from ischemic stroke by counteracting intracerebral thrombosis in the tMCAO model.L-Palmitoylcarnitine chloride (Palmitoyl-L-carnitine chloride) is a fatty acid metabolite with antithrombotic properties. Palmitoylcarnitine chloride inhibits the Na/K pump in the heart and inhibits FeCl 3-induced arterial thrombosis Attenuates intracerebral thrombosis and inflammation in a mouse model of transient middle cerebral artery occlusion (tMCAO). |
体外活性 | L-Palmitoylcarnitine chloride(1-20μM)以剂量依赖性方式抑制乙酰胆碱和P物质诱导的内皮依赖性松弛,而对静息张力和硝酸甘油诱导的松弛没有影响[1]。 |
体内活性 | 在体内,L-Palmitoylcarnitine chloride 可增加大鼠肠道对抗生素头孢西丁的吸收。 |
别名 | Palmitoyl-L-carnitine chloride |
分子量 | 436.07 |
分子式 | C23H46ClNO4 |
CAS No. | 18877-64-0 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | H2O: Slightly soluble, Sonication and heating are recommended. |
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