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HDAC8-IN-1 是一种 HDAC8 抑制剂,在癌细胞系中的 IC50 为 27.2 nM,有抗增殖作用。
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HDAC8-IN-1 是一种 HDAC8 抑制剂,在癌细胞系中的 IC50 为 27.2 nM,有抗增殖作用。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 197 | 现货 | |
5 mg | ¥ 413 | 现货 | |
10 mg | ¥ 672 | 现货 | |
25 mg | ¥ 1,350 | 现货 | |
50 mg | ¥ 2,020 | 现货 | |
100 mg | ¥ 2,980 | 现货 | |
200 mg | ¥ 3,970 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 463 | 现货 |
产品描述 | MDK-7933 (HDAC8-IN-1) is a HDAC8 inhibitor with an IC50 of 27.2 nM in cancer cell lines. MDK-7933 shows antiproliferative effects toward several human lung cancer cell lines (A549, H1299, and CL1-5). HDAC8-IN-1 exhibits cytotoxicity against human lung CL1-5 cells without significant cytotoxicity for normal IMR-90 cells[1]. |
靶点活性 | HDAC8:27.2 nM |
分子量 | 345.39 |
分子式 | C22H19NO3 |
CAS No. | 1417997-93-3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 55 mg/mL (159.24 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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