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AZ-1355是一种新型二苯并恶西平衍生物,具有降脂效果。
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AZ-1355是一种新型二苯并恶西平衍生物,具有降脂效果。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,270 | 现货 | |
5 mg | ¥ 2,970 | 现货 | |
10 mg | ¥ 4,230 | 现货 | |
25 mg | ¥ 6,590 | 现货 | |
50 mg | ¥ 8,920 | 现货 | |
100 mg | ¥ 11,800 | 现货 | |
200 mg | ¥ 16,200 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 2,760 | 现货 |
产品描述 | AZ-1355 is a novel dibenzoxepine derivative with lipid-lowering properties. |
体内活性 | AZ-1355 (150 mg/kg) reproducibly lowers serum total cholesterol (TC) in the Triton hyperlipidemic mice. AZ-1355 (50 mg/kg) significantly reduces serum TG and the 100 mg/kg dose results in serum TC and TG reduction in rats. AZ-1355 (100 mg/kg) reduces total liver TC in rats fed CE-2, and the 50 mg/kg dose reduces hepatic TC in rats fed the high-fat diet on both bases, and it also reduces the total hepatic TG of the CE-2 fed rats[1]. |
细胞实验 | The lipid-lowering profile in rodents AZ-1355, A New Dibenzoxazepine Derivative |
动物实验 | AZ-1355 (150 mg/kg) reproducibly lowers serum total cholesterol (TC) in the Triton hyperlipidemic mice. AZ-1355 (50 mg/kg) significantly reduces serum TG and the 100 mg/kg dose results in serum TC and TG reduction in rats. AZ-1355 (100 mg/kg) reduces total liver TC in rats fed CE-2, and the 50 mg/kg dose reduces hepatic TC in rats fed the high-fat diet on both bases, and it also reduces the total hepatic TG of the CE-2 fed rats. |
分子量 | 299.32 |
分子式 | C17H17NO4 |
CAS No. | 75451-07-9 |
Smiles | O(C)C1=C2C(CNC=3C(O2)=CC=C(C(OCC)=O)C3)=CC=C1 |
密度 | 1.2g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 22.5 mg/mL (75.17 mM) | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
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