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Imipenem (MK0787) 是一种噻吩霉素衍生物,属于抗生素类,具有抗菌活性,对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。
Imipenem (MK0787) 是一种噻吩霉素衍生物,属于抗生素类,具有抗菌活性,对革兰氏阳性和革兰氏阴性菌具有部分的抑制作用。Imipenem 可用于研究碳青霉烯类非易感性感染和铜绿假单胞菌生物膜感染。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
50 mg | ¥ 343 | 现货 |
产品描述 | Imipenem (MK0787) is a thienomycin derivative that belongs to the class of antibiotics with antibacterial activity and partial inhibition against gram-positive and gram-negative bacteria. Imipenem can be used to study carbapenem non-susceptible infections and Pseudomonas aeruginosa biofilm infections. |
体内活性 | In a neutropenic mouse model of biofilm lung infection, the pharmacokinetic parameters of Imipenem (MK0787) were assessed following a single intraperitoneal (IP) administration at various doses (4 mg/kg, 8 mg/kg, 16 mg/kg, 32 mg/kg, 64 mg/kg). The killing effect was observed to be time-dependent[3]. |
别名 | 亚胺培南, N-Formimidoyl thienamycin, MK0787 |
分子量 | 299.35 |
分子式 | C12H17N3O4S |
CAS No. | 64221-86-9 |
Smiles | C[C@@H](O)[C@@H]1[C@H]2CC(SCCNC=N)=C(N2C1=O)C(O)=O |
存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||
溶解度信息 | DMSO: 2.99 mg/mL (10 mM), Sonication is recommended. | ||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||
DMSO
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