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HKB99 是磷酸甘油酸突变酶 1(PGAM1) 的变构抑制剂,抑制非小细胞肺癌的生长和转移。HKB99 与EGFR抑制剂具有协同作用,可协助EGFR抑制剂杀瘤。HKB99 促进氧化应激,可诱导多种信号通路发生变化。HKB99 可用于研究代谢相关疾病。
HKB99 是磷酸甘油酸突变酶 1(PGAM1) 的变构抑制剂,抑制非小细胞肺癌的生长和转移。HKB99 与EGFR抑制剂具有协同作用,可协助EGFR抑制剂杀瘤。HKB99 促进氧化应激,可诱导多种信号通路发生变化。HKB99 可用于研究代谢相关疾病。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,790 | 现货 | |
5 mg | 询价 | 现货 |
产品描述 | HKB99 is a mutant inhibitor of phosphoglycerate mutase 1 (PGAM1), which inhibits the growth and metastasis of non-small cell lung cancer.HKB99 acts synergistically with EGFR inhibitors and assists in the killing of tumors by EGFR inhibitors.HKB99 promotes oxidative stress, which induces alterations in a variety of signaling pathways.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases.HKB99 can be used in the study of metabolism-related diseases. |
分子量 | 450.46 |
分子式 | C23H18N2O6S |
CAS No. | 2414908-90-8 |
Smiles | O=C1C=2C=CC=CC2C(=O)C3=C(O)C(O)=C(C=C13)NS(=O)(=O)C4=CC=C(C=C4)N5CCC5 |
密度 | 1.598 g/cm3 (Predicted) |
存储 | store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 100 mg/mL (222.00 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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