D-Panthenol (D-Pantothenyl alcohol) is an alcoholic analogue of D-pantothenic acid and cholinergic agent. D-Panthenol acts as a precursor of coenzyme A necessary for acetylation reactions and is involved in the synthesis of acetylcholine. Although the exact mechanism of the actions of D-Panthenol is unclear, it may enhance the effect of acetylcholine. D-Panthenol acts on the gastrointestinal tract and increases lower intestinal motility. It is also applied topically to the skin to relieve itching and to promote healing.

Dexpanthenol 对缺血再灌注后脑组织的保护具有积极效果[1]。Dexpanthenol 的局部应用在临床实践中广泛用于促进伤口愈合。在局部处理的样本中，已确认IL-6、IL-1、CYP1B1、CXCL1、CCL18及KAP 4-2基因表达的上调以及psorasin mRNA和蛋白表达的下调[2]。