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STAT5-IN-2 是一种具有抗白血病作用的 STAT5 抑制剂(EC50:在 K562 和 KU812 细胞中分别为 9 μM 和 5 μM)。
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STAT5-IN-2 是一种具有抗白血病作用的 STAT5 抑制剂(EC50:在 K562 和 KU812 细胞中分别为 9 μM 和 5 μM)。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 648 | 现货 | |
2 mg | ¥ 930 | 现货 | |
5 mg | ¥ 1,490 | 现货 | |
10 mg | ¥ 2,250 | 现货 | |
25 mg | ¥ 4,480 | 现货 | |
50 mg | ¥ 5,920 | 现货 | |
100 mg | ¥ 8,160 | 现货 | |
1 mL x 10 mM (in DMSO) | ¥ 1,630 | 现货 |
产品描述 | STAT5-IN-2 is an inhibitor of STAT5 with antileukemic effects (EC50s: 9 μM and 5 μM in K562 and KU812 cells, respectively). |
靶点活性 | K562 cells:(EC50)9 μM, KU812 cells:5 μM(EC50) |
体外活性 | STAT5-IN-2 (100 nM-50 µM) inhibits cell growth in KG1a and MV-4-11 cell lines with EC50 values of 2.6 µM and 3.5 µM, respectively. In K562, KU812, KG1a and MV-4-11 cells, STAT5-IN-2 (10 µM) induces apoptosis. In KG1a, MV-4-11 and KU812 cells, STAT5-IN-2 (10 µM) blocks the phosphorylation of STAT5[1]. |
分子量 | 397.51 |
分子式 | C26H27N3O |
CAS No. | 2111834-61-6 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 90 mg/mL (226.4 mM), Sonication is recommended. | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
DMSO
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