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WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM).
WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM).
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
2 mg | ¥ 889 | 5日内发货 | |
5 mg | ¥ 1,710 | 5日内发货 | |
25 mg | ¥ 5,900 | 10-14周 | |
50 mg | ¥ 7,670 | 10-14周 | |
100 mg | ¥ 11,800 | 10-14周 |
产品描述 | WEHI-539 hydrochloride is a selective Bcl-XL inhibitor (IC50: 1.1 nM). |
靶点活性 | BCL-XL:1.1 nM |
体外活性 | WEHI-539 hydrochloride is a selective Bcl-XL inhibitor. WEHI-539 augments NSC 241240 induced caspase 3/7 activity, PARP cleavage and annexin V labelling. WEHI-539 as a single agent causes noticeable PARP cleavage in Ovcar-4 (5 μM in Ovcar-4.) and Ovsaho (1 μM in Ovsaho) cells[2]. |
分子量 | 620.18 |
分子式 | C31H30ClN5O3S2 |
CAS No. | 2070018-33-4 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | ||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 50 mg/mL (80.62 mM), Sonication is recommended. | ||||||||||||||||||||||||||||||
溶液配制表 | |||||||||||||||||||||||||||||||
DMSO
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