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UUN44923 是脂肪及肥胖相关酶(FTO) 抑制剂(IC50<1 μM)。其中FTO-IN-1 (UUN44923) 可用于研究癌症。
UUN44923 是脂肪及肥胖相关酶(FTO) 抑制剂(IC50<1 μM)。其中FTO-IN-1 (UUN44923) 可用于研究癌症。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 485 | 现货 | |
5 mg | ¥ 880 | 现货 | |
10 mg | ¥ 1,450 | 现货 | |
25 mg | ¥ 2,580 | 现货 | |
50 mg | ¥ 4,000 | 现货 | |
100 mg | ¥ 6,500 | 现货 | |
500 mg | ¥ 17,500 | 现货 |
产品描述 | UUN44923 is a FTO inhibitor. It may be useful for treating diseases assocd. with FTO targets, obesity, metabolic syndrome (MS) , type 2 diabetes (T2D) , Alzheimer's diseases, breast cancers, small- cell lung cancers, a human bone marrow striated muscle cancer, a pancreatic cancer, malignant glioblastoma and the like. |
靶点活性 | FTO:<1 μM (IC50) |
别名 | UUN44923 |
分子量 | 391.25 |
分子式 | C18H16Cl2N4O2 |
CAS No. | 2243944-92-3 |
Smiles | CC=1C(C2=CC(Cl)=C(NC3=C(C(NO)=O)C=CC=C3)C(Cl)=C2)=C(C)NN1 |
密度 | 1.448 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. | |||||||||||||||||||||||||||||||||||
溶解度信息 | DMSO: 1 mg/ml, Sonication is recommended. Ethanol: 80 mg/mL (199.79 mM) | |||||||||||||||||||||||||||||||||||
溶液配制表 | ||||||||||||||||||||||||||||||||||||
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