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Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1].
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | 询价 | 期货 | |
500 mg | 询价 | 期货 |
产品描述 | Thalidomide-O-amido-PEG3-C2-NH2 is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and 2-unit PEG linker used in PROTAC technology[1]. |
体外活性 | PROTACs consist of two distinct ligands connected by a linker: one ligand targets an E3 ubiquitin ligase and the other targets the [target protein]. These compounds leverage the intracellular ubiquitin-proteasome system to selectively degrade [target proteins]. |
别名 | Thalidomide-NH-PEG2-C2-NH2 |
分子量 | 404.42 |
分子式 | C19H24N4O6 |
CAS No. | 2093416-32-9 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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