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MCL0020 是一种有效的选择性黑素皮质素MC4受体拮抗剂,IC50为 11.63 nM。它剂量依赖性减轻束缚应激诱发的厌食症,在体内表现出抗焦虑样活性。
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MCL0020 是一种有效的选择性黑素皮质素MC4受体拮抗剂,IC50为 11.63 nM。它剂量依赖性减轻束缚应激诱发的厌食症,在体内表现出抗焦虑样活性。
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
1 mg | ¥ 1,120 | 现货 | |
5 mg | ¥ 2,730 | 现货 | |
10 mg | ¥ 3,880 | 现货 | |
25 mg | ¥ 5,730 | 现货 | |
50 mg | ¥ 7,730 | 现货 | |
100 mg | ¥ 10,380 | 现货 | |
200 mg | ¥ 13,800 | 现货 |
产品描述 | MCL0020 is a potent and selective melanocortin MC4 receptor antagonist (IC50 values are 11.63, 1115 and > 10 000 nM at MC4, MC3 and MC1 receptors respectively). Significantly reverses stress-induced anorexia but has no effect on food intake in free-feeding rats. Exhibits anxiolytic-like activity in vivo. |
别名 | MCL 0020 |
分子量 | 609.72 |
分子式 | C34H39N7O4 |
CAS No. | 475498-26-1 |
Smiles | C([C@H](C(N[C@H](C(N[C@@H](CC1=CC2=C(C=C1)C=CC=C2)C(N)=O)=O)CCCNC(=N)N)=O)NC(C)=O)C3=CC4=C(C=C3)C=CC=C4 |
密度 | no data available |
存储 | keep away from moisture | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
溶解度信息 | 25% ethanol / water: 2 mg/mL |
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