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Pomalidomide-C4-NH2 hydrochloride is a synthesized conjugate comprising an E3 ligase ligand-linker. This compound incorporates the cereblon ligand derived from Pomalidomide and a linker that is commonly employed in PROTAC technology.
Pomalidomide-C4-NH2 hydrochloride is a synthesized conjugate comprising an E3 ligase ligand-linker. This compound incorporates the cereblon ligand derived from Pomalidomide and a linker that is commonly employed in PROTAC technology.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
100 mg | 询价 | 5日内发货 |
产品描述 | Pomalidomide-C4-NH2 hydrochloride is a synthesized conjugate comprising an E3 ligase ligand-linker. This compound incorporates the cereblon ligand derived from Pomalidomide and a linker that is commonly employed in PROTAC technology. |
体外活性 | PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[2]. |
别名 | Pomalidomide-C4-NH2 hydrochloride |
分子量 | 380.83 |
分子式 | C17H21ClN4O4 |
CAS No. | 2162120-73-0 |
密度 | no data available |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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