m-PEG8-succinimidyl carbonate is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
m-PEG8-succinimidyl carbonate is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
m-PEG8-succinimidyl carbonate is a polyethylene glycol (PEG)-derived linker, specifically designed for the synthesis of PROteolysis TArgeting Chimeras (PROTACs)[1].
体外活性
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
化学信息
分子量
525.54
分子式
C22H39NO13
CAS No.
1372860-04-2
储存&溶解度
存储
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