Kushenol X

Name: Kushenol X
Brand: TargetMol
SKU: TN1847
Price: 296 USD
Availability: InStock
Rating: 4.5 (1 reviews)

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产品编号 TN1847Cas号 254886-77-6

别名 苦参醇X

Kushenol X exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).

还可以

产品编号 TN1847 别名 苦参醇XCas号 254886-77-6

Kushenol X exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).

规格	价格	库存	数量
5 mg	¥ 14,800	期货
1 mL x 10 mM (in DMSO)	¥ 17,800	期货

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产品介绍

生物活性

产品描述	Kushenol X exhibits inhibitory activity against Sodium-dependent glucose cotransporter 2(SGLT2).
靶点活性	β-glucuronidase:2.07 μM (IC50), CES2A (human):3.05 μM (IC50)
体外活性	Sixteen lavandulyl flavonoids were isolated and their structures were elucidated as kushenol H(1),kushenol K(2),kurarinol(3),kushenol Y(4),kushenol P(5),norkurarinone(6),kushenol I(7),kushenol N(8),(-)-kurarinone(9),Kushenol X(10),neokurarinol(11),kushenol C(12),sophoraflavanone G(13),leachianone A(14),kuraridine(15)and kushenol A(16). All isolated compounds exhibited inhibitory activity against SGLT2. Among them,the two main constituents of the active EtOAc fraction,(-)-kurarinone(9)and sophoraflavanone G(13)showed the most potential inhibitory activity against SGLT2with the IC50values of 2.24μmol/L and 1.45μmol/L,respectively.
别名	苦参醇X