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FPI-1523
还可以产品编号 T38940Cas号 1452459-50-5
FPI-1523, a derivative of Avibactam, is a potent inhibitor of β-lactamase enzymes. It has Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. Additionally, FPI-1523 inhibits PBP2 with an IC50 of 3.2 μM and demonstrates significant antimicrobial activity.
FPI-1523
还可以产品编号 T38940Cas号 1452459-50-5
FPI-1523, a derivative of Avibactam, is a potent inhibitor of β-lactamase enzymes. It has Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. Additionally, FPI-1523 inhibits PBP2 with an IC50 of 3.2 μM and demonstrates significant antimicrobial activity.
| 规格 | 价格 | 库存 | 数量 |
|---|---|---|---|
| 5 mg | 询价 | 期货 |
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化学信息
| 产品描述 | FPI-1523, a derivative of Avibactam, is a potent inhibitor of β-lactamase enzymes. It has Kd values of 4 nM and 34 nM for CTX-M-15 and OXA-48, respectively. Additionally, FPI-1523 inhibits PBP2 with an IC50 of 3.2 μM and demonstrates significant antimicrobial activity. |
| 体外活性 | FPI-1523 inhibits K12 E. coli K12 and PBP2, with MIC and IC 50 of 4 μg/mL and 0.4 μg/mL, respectively[1]. FPI-1523 inhibit E. coli BW25113 pGDP-2 transformants either with an empty vector or expressing different β-lactamases, with low MICs (1-2 μM)[1]. |
| 分子量 | 322.29 |
| 分子式 | C9H14N4O7S |
| CAS No. | 1452459-50-5 |
储存&溶解度
| 存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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体内实验配液计算器
请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：
比如您的给药剂量是 10 mg/kg ，每只动物体重 20 g ，给药体积 100 μL ， 
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