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Desmethylxanthohumol shows estrogenic activity.
Desmethylxanthohumol shows estrogenic activity.
产品描述 | Desmethylxanthohumol shows estrogenic activity. |
体外活性 | The present study examines the dynamics of the hop prenylphenol, Desmethylxanthohumol (DMX), by means of quantitative 1H-NMR (qHNMR) in a setting that mimics in vitro and physiological conditions. The experiments provide a comprehensive, time-resolved, and mechanistic picture of the spontaneous isomerization of DMX into congeneric flavanones, including their 1H/2D isotopomers. Formation of the potent phytoestrogen, 8-prenylnaringenin (8PN), suggests that measurable estrogenic activity even of high-purity DMX is an artifact. Together with previously established qHNMR assays including purity activity relationships (PARs), dynamic qHNMR assays complement important steps of the post-isolation evaluation of natural products. |
别名 | 去甲黄腐醇 |
分子量 | 340.37 |
分子式 | C20H20O5 |
CAS No. | 115063-39-3 |
密度 | 1.312g/cm3 |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
中药材名称 | 中药材拉丁名 | 性 | 味 | 归经 |
---|---|---|---|---|
啤酒花 | Humulus lupulus L. | 微凉 | 苦 | 肝, 胃 |
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