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CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin. CNX-500 has inhibitory activity against Btk (IC50: 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase EGFR and upstream Src-family kinases.
CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin. CNX-500 has inhibitory activity against Btk (IC50: 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase EGFR and upstream Src-family kinases.
规格 | 价格 | 库存 | 数量 |
---|---|---|---|
5 mg | ¥ 18,400 | 期货 | |
10 mg | ¥ 27,900 | 期货 |
产品描述 | CNX-500 is a probe consisting of a covalent Btk inhibitor chemically linked to biotin. CNX-500 has inhibitory activity against Btk (IC50: 0.5 nM) and the ability to form a covalent bond with Btk. CNX-500 has low inhibitory effects on kinase EGFR and upstream Src-family kinases. |
体外活性 | In Ramos cells exposed to a range of CC-292 concentrations, the amount of Btk captured by the probe is compared with untreated samples and the extent of Btk bonded is demonstrated to be proportional to CC-292 drug concentration. |
分子量 | 961.18 |
分子式 | C48H68N10O9S |
CAS No. | 1202758-21-1 |
密度 | 1.232 g/cm3 (Predicted) |
存储 | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice. |
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